Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Qiongzi Qiu"'
Autor:
Yong Liu, Jing Huang, Rajan Pandey, Pengyuan Liu, Bhavika Therani, Qiongzi Qiu, Sridhar Rao, Aron M. Geurts, Allen W. Cowley, Andrew S. Greene, Mingyu Liang
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background A common feature of single-cell RNA-seq (scRNA-seq) data is that the number of cells in a cell cluster may vary widely, ranging from a few dozen to several thousand. It is not clear whether scRNA-seq data from a small number of ce
Externí odkaz:
https://doaj.org/article/47cf9339076f4b95a6c6e5db2b4711be
Autor:
Mengqian Yu, Jiani Yi, Qiongzi Qiu, Dongxia Yao, Jia Li, Juze Yang, Chunyi Mi, Liyuan Zhou, Bingjian Lu, Weiguo Lu, Kejing Ying, Wantao Chen, Enguo Chen, Honghe Zhang, Zhimin Lu, Yan Lu, Pengyuan Liu
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113408- (2023)
Summary: Transfer RNA-derived fragments (tRFs) are a class of small non-coding regulatory RNAs that are involved in the pathophysiology of many diseases. However, the role of tRFs in cancer progression remains largely elusive. Here, we demonstrate th
Externí odkaz:
https://doaj.org/article/de633d8206fb4455896bcd63cd57e29c
Autor:
Aoran Luo, Xiaoxiao Lan, Qiongzi Qiu, Qing Zhou, Jia Li, Mengting Wu, Pengyuan Liu, Honghe Zhang, Bingjian Lu, Yan Lu, Weiguo Lu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-13 (2022)
Abstract Long non-coding RNAs (lncRNAs) play key roles in cancer development and progression. However, the biological function and clinical significance of most lncRNAs in cervical cancer remain elusive. In this study, we explore the function and mec
Externí odkaz:
https://doaj.org/article/e53563d6ab36437faed2c1b0a15e81c0
Autor:
Juze Yang, Xinyi Qian, Qiongzi Qiu, Lingling Xu, Meidie Pan, Jia Li, Jiayi Ren, Bingjian Lu, Ting Qiu, Enguo Chen, Kejing Ying, Honghe Zhang, Yan Lu, Pengyuan Liu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-13 (2022)
Abstract Long non-coding RNAs (lncRNAs) is known to play vital roles in modulating tumorigenesis. We previously reported that LCAT1, a novel lncRNA, promotes the growth and metastasis of lung cancer cells both in vitro and in vivo. However, the under
Externí odkaz:
https://doaj.org/article/5b37e644aa974f94b3299a9c73138aa1
Autor:
Mengting Wu, Qiongzi Qiu, Qing Zhou, Jia Li, Juze Yang, Chengcai Zheng, Aoran Luo, Xufan Li, Honghe Zhang, Xiaodong Cheng, Weiguo Lu, Pengyuan Liu, Bingjian Lu, Yan Lu
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background CircRNAs are a novel class of evolutionarily conserved noncoding RNA molecules that form covalently closed continuous loop structures without 5′ caps and 3′ poly(A) tails. Accumulating evidence suggests that circRNAs play impo
Externí odkaz:
https://doaj.org/article/c4cf1b04f1dd4ff28627db07b46177af
Autor:
Liyuan Zhou, Qiongzi Qiu, Qing Zhou, Jianwei Li, Mengqian Yu, Kezhen Li, Lingling Xu, Xiaohui Ke, Haiming Xu, Bingjian Lu, Hui Wang, Weiguo Lu, Pengyuan Liu, Yan Lu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The molecular mechanisms underlying cervical carcinogenesis following integration of HPV DNA into the human genome remain elusive. Here, the authors perform long-read sequencing in 16 HPV16-positive cervical tumors and identify distinct integration t
Externí odkaz:
https://doaj.org/article/c40d0acc9bc143a3b670401e65c9c657
Autor:
Xinyi Qian, Juze Yang, Qiongzi Qiu, Xufan Li, Chengxi Jiang, Jia Li, Liangliang Dong, Kejing Ying, Bingjian Lu, Enguo Chen, Pengyuan Liu, Yan Lu
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-19 (2021)
Abstract Background Long non-coding RNAs (lncRNAs) are important epigenetic regulators, which play critical roles in diverse physiological and pathological processes. However, the regulatory mechanism of lncRNAs in lung carcinogenesis remains elusive
Externí odkaz:
https://doaj.org/article/0add5097b2ed4ade86bfdf3fcf59e43a
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Abstract Occurring in over 60% of human genes, alternative polyadenylation (APA) results in numerous transcripts with differing 3’ends, thus greatly expanding the diversity of mRNAs and of proteins derived from a single gene. As a key molecular mec
Externí odkaz:
https://doaj.org/article/ee8c544323ef42cd88220946fc193428
Autor:
Juze Yang, Qiongzi Qiu, Xinyi Qian, Jiani Yi, Yiling Jiao, Mengqian Yu, Xufan Li, Jia Li, Chunyi Mi, Jisong Zhang, Bingjian Lu, Enguo Chen, Pengyuan Liu, Yan Lu
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-16 (2019)
Abstract Introduction Long noncoding RNAs (lncRNAs) are emerging as key players in the development and progression of cancer. However, the biological role and clinical significance of most lncRNAs in lung carcinogenesis remain unclear. In this study,
Externí odkaz:
https://doaj.org/article/7ac91ed7908d41d5abb4a509edf32f7c
Autor:
Lei Zhang, Qing Zhou, Qiongzi Qiu, Ling Hou, Mengting Wu, Jia Li, Xufan Li, Bingjian Lu, Xiaodong Cheng, Pengyuan Liu, Weiguo Lu, Yan Lu
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-19 (2019)
Abstract Background Emerging evidence has shown that circular RNAs (circRNAs) play essential roles in cancer biology and are potential biomarkers and targets for cancer therapy. However, the expression and function of circRNAs in ovarian carcinogenes
Externí odkaz:
https://doaj.org/article/a37862753c084b3cafe2c2f803f50126