Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Qiongqiong Angela Zhou"'
Autor:
Xiang Yu, Carmen Otilia Catanescu, Robert E. Bird, Sriram Satagopan, Zachary J. Baum, Leilani M. Lotti Diaz, Qiongqiong Angela Zhou
Publikováno v:
ACS Omega, Vol 8, Iss 13, Pp 11643-11664 (2023)
Externí odkaz:
https://doaj.org/article/a0550cf8d74a439c86eaa1d1721a1899
Publikováno v:
ACS Omega, Vol 7, Iss 37, Pp 32908-32935 (2022)
Externí odkaz:
https://doaj.org/article/9ff27d2d2f4f4492a8487c407668fb5e
Autor:
Janet M. Sasso, Rumiana Tenchov, DaSheng Wang, Linda S. Johnson, Xinmei Wang, Qiongqiong Angela Zhou
Publikováno v:
Biochemistry. 62:601-623
Targeted protein degradation is a rapidly exploding drug discovery strategy which uses small molecules to recruit disease-causing proteins for rapid destruction mainly via the ubiquitin-proteasome pathway. It shows great potential for treating diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0cb3a3501e769144fb86ca7e78df52
https://doi.org/10.1021/acs.biochem.2c00245
https://doi.org/10.1021/acs.biochem.2c00245
Publikováno v:
Bioconjugate Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdbda9df505073c8ed59762a621b2c70
https://doi.org/10.1021/acs.bioconjchem.3c00174
https://doi.org/10.1021/acs.bioconjchem.3c00174
Autor:
Janet M. Sasso, Barbara J. B. Ambrose, Rumiana Tenchov, Ruchira S. Datta, Matthew T. Basel, Robert K. DeLong, Qiongqiong Angela Zhou
Publikováno v:
Journal of Medicinal Chemistry. 65:6975-7015
In the past decade, there has been a shift in research, clinical development, and commercial activity to exploit the many physiological roles of RNA for use in medicine. With the rapid success in the development of lipid-RNA nanoparticles for mRNA va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9e6503a62eaa5b982f506b7a552858
https://doi.org/10.1021/acs.jmedchem.2c00024
https://doi.org/10.1021/acs.jmedchem.2c00024
Publikováno v:
ACS Infectious Diseases. 8:422-432
Since the beginning of the COVID-19 pandemic caused by SARS-CoV-2, millions of patients have been diagnosed and many of them have died from the disease worldwide. The identification of novel therapeutic targets are of utmost significance for preventi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ad5959b8115689014aefa4f389a53c
https://doi.org/10.1021/acsinfecdis.2c00031
https://doi.org/10.1021/acsinfecdis.2c00031
Autor:
Rumiana Tenchov, Janet M. Sasso, Xinmei Wang, Wen-Shing Liaw, Chun-An Chen, Qiongqiong Angela Zhou
Publikováno v:
ACS nano. 16(11)
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer membrane and secreted by most eukaryotic cells. They represent a route of intercellular communication and participate in a wide variety of physiological and patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c5b962cd61c3822a09efe9f0da6834
https://pubmed.ncbi.nlm.nih.gov/36354238
https://pubmed.ncbi.nlm.nih.gov/36354238
Autor:
Xiang Yu, Carmen Otilia Catanescu, Robert Bird, Sriram Satagopan, Zachary J. Baum, Qiongqiong Angela Zhou
Technological and medical advances over the past few decades epitomize human capabilities. However, the increased life expectancies and concomitant land-use changes have significantly contributed to the release of ~830 gigatons of CO2 into the atmosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1893297365239cbe50d322951ab93f4
https://doi.org/10.26434/chemrxiv-2022-j39b0
https://doi.org/10.26434/chemrxiv-2022-j39b0
Publikováno v:
Bioconjugate chemistry. 32(12)
Bioorthogonal chemistry is a set of methods using the chemistry of non-native functional groups to explore and understand biology in living organisms. In this review, we summarize the most common reactions used in bioorthogonal methods, their relativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430f56605bfdefbbfe7281bfad554f97
https://pubmed.ncbi.nlm.nih.gov/34846126
https://pubmed.ncbi.nlm.nih.gov/34846126
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781071613658
As research continues into the SARS-CoV-2 infection process, many viral and human proteins and other biomolecules have been identified as potential drug targets for treating this and other coronavirus infections. The most therapeutically promising of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ad9244400c688714bda0524e81e652
https://doi.org/10.1007/7653_2020_64
https://doi.org/10.1007/7653_2020_64