Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Qiongling Wang"'
Autor:
Jing Zhou, Yuexu Jiang, Yue Huang, Qiongling Wang, Jussuf T. Kaifi, Eric T. Kimchi, Chiswili Yves Chabu, Zhenguo Liu, Trupti Joshi, Guangfu Li
Publikováno v:
Translational Oncology, Vol 15, Iss 1, Pp 101262- (2022)
Pancreatic cancer (PaC) is resistant to immune checkpoint therapy, but the underlying mechanisms are largely unknown. In this study, we have established four orthotopic PaC murine models with different PaC cell lines by intra-pancreatic inoculation.
Externí odkaz:
https://doaj.org/article/a21934920a644ea9857ba22b86db5b6e
Autor:
Xinjian Liu, Hao Yuan, Jing Zhou, Qiongling Wang, Xiaoqiang Qi, Catharine Bernal, Diego Avella, Jussuf T. Kaifi, Eric T. Kimchi, Parrett Timothy, Kun Cheng, Yi Miao, Kuirong Jiang, Guangfu Li
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Pancreatic cancer (PC) is one of the most lethal human malignancies without effective treatment. In an effort to discover key genes and molecular pathways underlying PC growth, we have identified LIM domain only 7 (LMO7) as an under-investigated mole
Externí odkaz:
https://doaj.org/article/17e7022924fb4f8badc772f7ebad5284
Publikováno v:
Metals, Vol 12, Iss 4, p 579 (2022)
Considering environmental friendliness and economic factors, the separation and extraction of indium under acidic conditions are of great significance. In this research, metal-organic frameworks (MOFs) of UiO-66 were successfully prepared and used fo
Externí odkaz:
https://doaj.org/article/65f6a3662faa440aaad1c6952a7459b1
Autor:
Ann P. Quick, BA, Andrew P. Landstrom, MD, PhD, Qiongling Wang, PhD, David L. Beavers, MD, PhD, Julia O. Reynolds, BS, Giselle Barreto-Torres, PhD, Viet Tran, MD, Jordan Showell, BS, Leonne E. Philippen, MSc, Shaine A. Morris MD, MPH, Darlene Skapura, BS, J. Martijn Bos, MD, Steen E. Pedersen, PhD, Robia G. Pautler, PhD, Michael J. Ackerman, MD, PhD, Xander H.T. Wehrens, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 1, Pp 56-67 (2017)
Summary: Junctophilin-2 (JPH2) is a structural calcium (Ca2+) handling protein, which approximates the cardiomyocyte transverse tubules (TTs) to the sarcoplasmic reticulum. This facilitates communication of the voltage-gated Ca2+ channel and the ryan
Externí odkaz:
https://doaj.org/article/d086c9c35bcd4a099db4e3951cde466e
Autor:
Jimmonique Donelson, Qiongling Wang, Tanner O. Monroe, Xiqian Jiang, Jianjie Zhou, Han Yu, Qianxing Mo, Qin Sun, Juan C. Marini, Xinquan Wang, Paul A. Nakata, Kendal D. Hirschi, Jin Wang, George G. Rodney, Xander H.T. Wehrens, Ninghui Cheng
Publikováno v:
Physiological Reports, Vol 7, Iss 8, Pp n/a-n/a (2019)
Abstract Growing evidence suggests that redox‐sensitive proteins including glutaredoxins (Grxs) can protect cardiac muscle cells from oxidative stress‐induced damage. Mammalian Grx3 has been shown to be critical in regulating cellular redox state
Externí odkaz:
https://doaj.org/article/b3c877fa26e2425991ebeb043f67aa6d
Autor:
Curtis A. Nutter, Elizabeth A. Jaworski, Sunil K. Verma, Vaibhav Deshmukh, Qiongling Wang, Olga B. Botvinnik, Mario J. Lozano, Ismail J. Abass, Talha Ijaz, Allan R. Brasier, Nisha J. Garg, Xander H.T. Wehrens, Gene W. Yeo, Muge N. Kuyumcu-Martinez
Publikováno v:
Cell Reports, Vol 15, Iss 10, Pp 2200-2213 (2016)
Alternative splicing (AS) defects that adversely affect gene expression and function have been identified in diabetic hearts; however, the mechanisms responsible are largely unknown. Here, we show that the RNA-binding protein RBFOX2 contributes to tr
Externí odkaz:
https://doaj.org/article/f09eb567819d4e2c8c1ab926ef5e3d91
Autor:
Cristina E. Molina, Issam H. Abu-Taha, Qiongling Wang, Elena Roselló-Díez, Marcus Kamler, Stanley Nattel, Ursula Ravens, Xander H. T. Wehrens, Leif Hove-Madsen, Jordi Heijman, Dobromir Dobrev
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Atrial fibrillation (AF) and heart failure (HF) are common cardiovascular diseases that often co-exist. Animal models have suggested complex AF-promoting atrial structural, electrical, and Ca2+-handling remodeling in the setting of HF, but data in hu
Externí odkaz:
https://doaj.org/article/1962b8dcc1f442a2a39a855142be13a1
Autor:
Stephan R Künzel, Ursula Ravens, Markus Kamler, Tina Veleva, Jordi Heijman, Stanley Nattel, Cristina E. Molina, Henry Sutanto, Na Li, Marcel A Tekook, Xander H.T. Wehrens, Dobromir Dobrev, Issam Abu-Taha, Qiongling Wang, Marcel Gorka, Ali El-Armouche, Hermann Reichenspurner, Viacheslav O. Nikolaev, Azinwi Phina Muna
Publikováno v:
Circ Res
Circulation Research, 127(8), 1036-1055. LIPPINCOTT WILLIAMS & WILKINS
Circulation Research, 127(8), 1036-1055. LIPPINCOTT WILLIAMS & WILKINS
Rationale: Postoperative atrial fibrillation (POAF) is a common and troublesome complication of cardiac surgery. POAF is generally believed to occur when postoperative triggers act on a preexisting vulnerable substrate, but the underlying cellular an
Autor:
Trupti Joshi, Yuexu Jiang, Chiswili Yves Chabu, Jing Zhou, Yue Huang, Guangfu Li, Zhenguo Liu, Qiongling Wang, Jussuf T. Kaifi, Eric T. Kimchi
Publikováno v:
Translational Oncology
Translational Oncology, Vol 15, Iss 1, Pp 101262-(2022)
Translational Oncology, Vol 15, Iss 1, Pp 101262-(2022)
Pancreatic cancer (PaC) is resistant to immune checkpoint therapy, but the underlying mechanisms are largely unknown. In this study, we have established four orthotopic PaC murine models with different PaC cell lines by intra-pancreatic inoculation.
Autor:
Robert M. Strongin, Na Li, Jonathan J. Abramson, Robert C. Klipp, Xander H.T. Wehrens, Martha Sibrian-Vazquez, Qiongling Wang, Tarah A. Word
Publikováno v:
Heart Rhythm. 15:578-586
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an arrhythmogenic disorder caused by mutations in the cardiac ryanodine receptor RyR2 that increase diastolic calcium cation (Ca2+) leak from the sarcoplasmic reticulum (SR).