Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Qiong Ke"'
Autor:
Gen Li, Meixing Yu, Qiong Ke, Jing Sun, Yanwen Peng, Chuanfeng Xiong, Olivia Monteiro, COVID-19 Infection and Immunity Investigation Group, Jincun Zhao, Andy P. Xiang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/39760765e73e4c0cbe1724247bea2634
Autor:
Kai Xia, Fulin Wang, Zhipeng Tan, Suyuan Zhang, Xingqiang Lai, Wangsheng Ou, Cuifeng Yang, Hong Chen, Hao Peng, Peng Luo, Anqi Hu, Xiang'an Tu, Tao Wang, Qiong Ke, Chunhua Deng, Andy Peng Xiang
Publikováno v:
Advanced Science, Vol 10, Iss 29, Pp n/a-n/a (2023)
Abstract Hereditary primary hypogonadism (HPH), caused by gene mutation related to testosterone synthesis in Leydig cells, usually impairs male sexual development and spermatogenesis. Genetically corrected stem Leydig cells (SLCs) transplantation may
Externí odkaz:
https://doaj.org/article/78c9cfd0946e4d86af4d4404da4ca640
Autor:
Huanyao Liu, Shanshan Huang, Weijia Wang, Huiyan Wang, Weijun Huang, Zhichen Zhai, Ding Wang, Yubao Fan, Jiaqi Sun, Dairui Li, Weicheng Chiu, Xingqiang Lai, Jixiao Zeng, Qiong Ke, Tao Wang, Andy Peng Xiang, Yong Yuan, Xinchun Zhang, Weiqiang Li
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-12 (2022)
Abstract Down syndrome (DS) is the most common chromosomal abnormality in live-born infants and is caused by trisomy of chromosome 21. Most individuals with DS display craniofacial dysmorphology, including reduced sizes of the skull, maxilla, and man
Externí odkaz:
https://doaj.org/article/6319d13f7d62494da8dd14299c2860d3
Autor:
Anqi Li, Zhuoran Li, Weicheng Chiu, Chuanfeng Xiong, Qian Chen, Junhua Chen, Xingqiang Lai, Weiqiang Li, Qiong Ke, Jia Liu, Xinchun Zhang
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3199 (2023)
Dental pulp pericytes are reported to have the capacity to generate odontoblasts and express multiple cytokines and chemokines that regulate the local immune microenvironment, thus participating in the repair of dental pulp injury in vivo. However, i
Externí odkaz:
https://doaj.org/article/7c616c457f1a4d5cbb5fdc3976fb5a60
Autor:
Hong Chen, Kai Xia, Weijun Huang, Huijian Li, Chao Wang, Yuanchen Ma, Jianhui Chen, Peng Luo, Shuwei Zheng, Jiancheng Wang, Yi Wang, Lin Dong, Zhipeng Tan, Xingqiang Lai, Frank Fuxiang Mao, Weiqiang Li, Xiaoyan Liang, Tao Wang, Andy Peng Xiang, Qiong Ke
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-16 (2021)
Abstract Premature ovarian insufficiency (POI) is defined as the loss of ovarian activity under the age of 40. Theca cells (TCs) play a vital role during folliculogenesis and TCs dysfunction participate in the pathogenesis of POI. Therefore, transpla
Externí odkaz:
https://doaj.org/article/f3ea83a6346d4039978fbae83d500322
Autor:
Jiaqi Sun, Yinong Huang, Jin Gong, Jiancheng Wang, Yubao Fan, Jianye Cai, Yi Wang, Yuan Qiu, Yili Wei, Chuanfeng Xiong, Jierui Chen, Bin Wang, Yuanchen Ma, Lihua Huang, Xiaoyong Chen, Shuwei Zheng, Weijun Huang, Qiong Ke, Tao Wang, Xiaoping Li, Wei Zhang, Andy Peng Xiang, Weiqiang Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Pericytes play an essential role in blood brain barrier (BBB) integrity. Here, the authors generate pericyte-like cells (PCs) from human pluripotent stem cells (hPSCs) which display functional properties and also promote BBB recovery in a mouse model
Externí odkaz:
https://doaj.org/article/c8098a945ee5461faca4a71cc390c57e
Autor:
Jiancheng Wang, Qiying Lu, Jianye Cai, Yi Wang, Xiaofan Lai, Yuan Qiu, Yinong Huang, Qiong Ke, Yanan Zhang, Yuanjun Guan, Haoxiang Wu, Yuanyuan Wang, Xin Liu, Yue Shi, Kang Zhang, Maosheng Wang, Andy Peng Xiang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Loss of Nestin sensitizes non-small cell lung carcinoma (NSCLC) to oxidative stress. Here, the authors report a feedback loop between Nestin and Nrf2 wherein Nestin competes with Nrf2 for Keap1 binding, preventing Nrf2 degradation, and show the Nesti
Externí odkaz:
https://doaj.org/article/b1b00c42536b4061b50abe0984df2505
Autor:
Yanan Zhang, Jiancheng Wang, Weijun Huang, Jianye Cai, Junhui Ba, Yi Wang, Qiong Ke, Yinong Huang, Xin Liu, Yuan Qiu, Qiying Lu, Xin Sui, Yue Shi, Tao Wang, Huiyong Shen, Yuanjun Guan, Ying Zhou, Yuan Chen, Maosheng Wang, Andy Peng Xiang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nestin can be localised in the nucleus of cancer cells, but its nuclear role in tumorigenesis is unclear. Here, the authors show that nuclear Nestin prevents senescence in tumor cells by stabilising lamin A/C from proteasomal degradation to maintain
Externí odkaz:
https://doaj.org/article/d48c676e77354d918de1fbd1372346c0
Autor:
Jiancheng Wang, Xin Liu, Yuan Qiu, Yue Shi, Jianye Cai, Boyan Wang, Xiaoyue Wei, Qiong Ke, Xin Sui, Yi Wang, Yinong Huang, Hongyu Li, Tao Wang, Ren Lin, Qifa Liu, Andy Peng Xiang
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-13 (2018)
Abstract Background Despite the high cure rate of T cell acute lymphoblastic leukemia (T-ALL), drug resistance to chemotherapy remains a significant clinical problem. Bone marrow mesenchymal stem cells (MSCs) protect leukemic cells from chemotherapy,
Externí odkaz:
https://doaj.org/article/c5821c0fdd9a40a5bd55e323b2355ed0
Autor:
Lei Shi, Lihua Huang, Ruojie He, Weijun Huang, Huiyan Wang, Xingqiang Lai, Zhengwei Zou, Jiaqi Sun, Qiong Ke, Minying Zheng, Xilin Lu, Zhong Pei, Huanxing Su, Andy Peng Xiang, Weiqiang Li, Xiaoli Yao
Publikováno v:
Stem Cell Reports, Vol 10, Iss 1, Pp 120-133 (2018)
Summary: Charcot-Marie-Tooth disease type 1A (CMT1A), one of the most frequent inherited peripheral neuropathies, is associated with PMP22 gene duplication. Previous studies of CMT1A mainly relied on rodent models, and it is not yet clear how PMP22 o
Externí odkaz:
https://doaj.org/article/2bc82fe790584c21a7c3bb57b921f0aa