Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Qinzi Yan"'
Autor:
Lina Guerra, Ami Albihn, Susanna Tronnersjö, Qinzi Yan, Riccardo Guidi, Bo Stenerlöw, Torsten Sterzenbach, Christine Josenhans, James G Fox, David B Schauer, Monica Thelestam, Lars-Gunnar Larsson, Marie Henriksson, Teresa Frisan
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8924 (2010)
The MYC protein controls cellular functions such as differentiation, proliferation, and apoptosis. In response to genotoxic agents, cells overexpressing MYC undergo apoptosis. However, the MYC-regulated effectors acting upstream of the mitochondrial
Externí odkaz:
https://doaj.org/article/f9d1a61ae3ac4f2fb16236f8f4b576aa
Autor:
Lars-Gunnar Larsson, John Inge Johnsen, Sven Nelander, Laura Baranello, Sören Lehmann, Per Hydbring, Loay Mahmoud, Sheryl Y. Lim, Linnéa Schmidt, Vasiliki Verschut, Thale Kristin Olsen, Cecilia Dyberg, Donald P. Cameron, Cecilia Krona, Marcela Franco, Mohammad Alzrigat, Malin Wickström, Fan Zhang, Wesam Bazzar, Karin Fawkner, Qinzi Yan, Alina Castell
Deregulated expression of MYC family oncogenes occurs frequently in human cancer and is often associated with aggressive disease and poor prognosis. While MYC is a highly warranted target, it has been considered “undruggable,” and no specific ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a431701aaf0ab30ac5e1fe7ec1b18f
https://doi.org/10.1158/2767-9764.c.6550598
https://doi.org/10.1158/2767-9764.c.6550598
Autor:
Fan Zhang, Wesam Bazzar, Jacob Goodwin, Lars Larsson, Per Hydbring, Alina Castell, Siti Mariam Zakaria, Karin Fawkner, Giovanna Zinzalla, Qinzi Yan, Marcela Franco, Vasiliki Verschut
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Scientific Reports
Scientific Reports
MYC is a key player in tumor development, but unfortunately no specific MYC-targeting drugs are clinically available. MYC is strictly dependent on heterodimerization with MAX for transcription activation. Aiming at targeting this interaction, we iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ef46eb079e83fee5a9b9902e9b86a1
https://doi.org/10.1038/s41598-018-28107-4
https://doi.org/10.1038/s41598-018-28107-4
Autor:
Marcela Franco, Giovanna Zinzalla, Alina Castell, Per Hydbring, Lars-Gunnar Larsson, Fan Zhang, Vasiliki Verschut, Karin Fawkner, Qinzi Yan
Publikováno v:
Cancer Research. 78:3952-3952
The MYC family oncoproteins/transcription factors MYC, MYCN and MYCL (here referred to as MYC) are key players in tumor development and are particularly associated with aggressive disease and poor prognosis. Efficient and specific MYC-targeting drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9c3f4230434555ae7feef507758034d
https://doi.org/10.1158/1538-7445.am2018-3952
https://doi.org/10.1158/1538-7445.am2018-3952
Autor:
Jacob Goodwin, Alina Castell, Lars-Gunnar Larsson, Inga Müller, Per Hydbring, Qinzi Yan, Fan Zhang, Siti Mariam Zakaria, Marcela Franco, Karin Ridderstråle, Lars Johansson
Publikováno v:
Cancer Research. 76:1227-1227
Deregulated expression of MYC family oncogenes MYC, MYCN and MYCL (here collectively referred to as MYC) occurs in many types of human tumors, and is often associated with aggressive tumor development and poor prognosis. In mouse tumor models, inacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::862e852d7daf277d0f64ea11a0c01a15
https://doi.org/10.1158/1538-7445.am2016-1227
https://doi.org/10.1158/1538-7445.am2016-1227
Autor:
Riccardo Guidi, Monica Thelestam, Ami Albihn, Lars-Gunnar Larsson, James G. Fox, Marie Henriksson, David B. Schauer, Lina Guerra, Torsten Sterzenbach, Teresa Frisan, Susanna Tronnersjö, Qinzi Yan, Bo Stenerlöw, Christine Josenhans
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 1, p e8924 (2010)
PLoS ONE, Vol 5, Iss 1, p e8924 (2010)
Background The MYC protein controls cellular functions such as differentiation, proliferation, and apoptosis. In response to genotoxic agents, cells overexpressing MYC undergo apoptosis. However, the MYC-regulated effectors acting upstream of the mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fe5173a7f8e536108b29dfa994a070
http://europepmc.org/articles/PMC2811743
http://europepmc.org/articles/PMC2811743
Autor:
Guerra, Lina, Albihn, Ami, Susanna Tronnersjö, Qinzi Yan, Guidi, Riccardo, Stenerlöw, Bo, Sterzenbach, Torsten, Josenhans, Christine, Fox, James G., Schauer, David B., Thelestam, Monica, Larsson, Lars-Gunnar, Henriksson, Marie, Frisan, Teresa
Publikováno v:
PLoS ONE; 2010, Vol. 5 Issue 1, p1-9, 9p, 6 Black and White Photographs, 1 Diagram, 4 Graphs