Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Qinyuan, Li"'
Autor:
Zhanbo Yang, Bizhu Chu, Yao Tu, Lulu Li, Dawei Chen, Shouhui Huang, Wenjun Huang, Weiwen Fan, Qinyuan Li, Cunlong Zhang, Zigao Yuan, Jumin Huang, Elaine Lai-Han Leung, Yuyang Jiang
Publikováno v:
Pharmacological Research, Vol 206, Iss , Pp 107271- (2024)
Colorectal cancer is the second most prevalent and deadly cancer worldwide. The emergence of immune checkpoint therapy has provided a revolutionary strategy for the treatment of solid tumors. However, less than 5 % of colorectal cancer patients respo
Externí odkaz:
https://doaj.org/article/ca91e1fabf424a50a93b262b7eca44e2
Dual inhibitors of DNMT and HDAC induce viral mimicry to induce antitumour immunity in breast cancer
Autor:
Wenjun Huang, Qingyun Zhu, Zhichao Shi, Yao Tu, Qinyuan Li, Wenwen Zheng, Zigao Yuan, Lulu Li, Xuyu Zu, Yue Hao, Bizhu Chu, Yuyang Jiang
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The existing conventional treatments for breast cancer, including immune checkpoint blockade, exhibit limited effects in some cancers, particularly triple-negative breast cancer. Epigenetic alterations, specifically DNMT and HDAC alterations
Externí odkaz:
https://doaj.org/article/72c030ec32424fb889eb162cf2f3b4fb
Autor:
Qingyun Zhu, Qiuzi Dai, Lei Zhao, Chang Zheng, Qinyuan Li, Zigao Yuan, Lulu Li, Zhuoye Xie, Zixuan Qiu, Wenjun Huang, Guowen Liu, Xuyu Zu, Bizhu Chu, Yuyang Jiang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract PARP inhibitors and HDAC inhibitors have been approved for the clinical treatment of malignancies, but acquired resistance of or limited effects on solid tumors with a single agent remain as challenges. Bioinformatics analyses and a combinat
Externí odkaz:
https://doaj.org/article/130f5bf9dcba44a29bcf23396af299cf
Autor:
Liangqin Yi, Yan Zhao, Ziyao Guo, Qinyuan Li, Chunlan Qiu, Jingyi Yang, Sha Liu, Fangjun Liu, Ximing Xu, Zhengxiu Luo
Publikováno v:
Pediatric Discovery, Vol 2, Iss 1, Pp n/a-n/a (2024)
Abstract Asthma control in children is often challenging. This retrospective cohort study aimed to investigate the potential contribution of small airway function in predicting asthma control within a 2‐ to 3‐month period following the initial di
Externí odkaz:
https://doaj.org/article/dbd0ff52dd5b46b9857bc9c1f3101d9d
Autor:
Liangqin Yi, Yan Zhao, Ziyao Guo, Qinyuan Li, Guangli Zhang, Xiaoyin Tian, Ximing Xu, Zhengxiu Luo
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Small airways are the major sites of inflammation and airway remodeling in all severities of asthma patients. However, whether small airway function parameters could reflect the airway dysfunction feature in preschool asthmatic ch
Externí odkaz:
https://doaj.org/article/8f04e4fc6b9e4bfda2e65f63de125da0
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background Currently, there are no reliable clinical tools available to identify persistent asthma symptoms among preschool children with recurrent wheezing. We investigated iron homeostasis in the airways of preschoolers with recurrent whee
Externí odkaz:
https://doaj.org/article/972b6efcc7b043c1a2379ea73cb3f4a4
Autor:
Jingjing Liu, Yanyan Wang, Qinyuan Li, Tao Liu, Xu Liu, Han Zhang, Zhifei Fu, Yifan Dai, Haiyuan Yang, Yu Wang, Ying Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115507- (2023)
Phenylethanoid glycosides derived from Cistanche deserticola (PhGs) are plant-derived natural medicinal compounds that occur in many medicinal plants. This study aims to investigate whether PhGs treatment improves the stroke and its potential mechani
Externí odkaz:
https://doaj.org/article/fbeda3ebb0b74f8a9c9c8e98f7f2107a
Autor:
Qi Zhou, Wenbo Meng, Yanhan Ren, Qinyuan Li, Marja A. Boermeester, Peter Muli Nthumba, Jennifer Rickard, Bobo Zheng, Hui Liu, Qianling Shi, Siya Zhao, Zijun Wang, Xiao Liu, Zhengxiu Luo, Kehu Yang, Yaolong Chen, Robert G. Sawyer
Publikováno v:
World Journal of Emergency Surgery, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Background Intraoperative peritoneal lavage (IOPL) with saline has been widely used in surgical practice. However, the effectiveness of IOPL with saline in patients with intra-abdominal infections (IAIs) remains controversial. This study aim
Externí odkaz:
https://doaj.org/article/3c1864c6ab764fc2b98aaf2159d1d666
Autor:
Jie Cheng, Qinyuan Li, Guangli Zhang, Huiting Xu, Yuanyuan Li, Xiaoyin Tian, Dapeng Chen, Zhengxiu Luo
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract We tend to investigate the connection between time to appropriate therapy (TTAT) and prognosis in pediatric patients with nosocomial Klebsiella pneumoniae (K. pneumoniae) bloodstream infection, and find the optimal cutoff point for the empir
Externí odkaz:
https://doaj.org/article/39ed931ebe8940d985a75ea96365455c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Asthma is the most common chronic condition in children, with allergic asthma being the most common phenotype, accounting for approximately 80% of cases. Growing evidence suggests that disruption of iron homeostasis and iron regulatory
Externí odkaz:
https://doaj.org/article/e49aaf0f6a4d48d9b508ec382011f5f8