Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Qinshu Zhou"'
Autor:
Pengjuan Li, Jun Li, Yong-qing Tang, Dandan Liang, Qin Pan, Yiqing Yang, Jun Ma, Yi Liu, Qinshu Zhou, Yi-Han Chen, Junjie Xiao, Luying Peng, Hong Zhang
Publikováno v:
Molecular Biology Reports. 37:1329-1333
The KCNQ1 channel is abundantly expressed in the gastric parietal cells. Although the functional coupling of KCNQ1 with the H(+)/K(+)-ATPase has already been confirmed on the basis of pharmacological kinetics, the effect of a KCNQ1 loss-of-function m
Publikováno v:
Biochemical and Biophysical Research Communications. 351:462-467
The inward rectifier potassium channel, Kir2.1, contributes to the I(K1) current in cardiac myocytes and is closely associated with atrial fibrillation. Strong evidences have shown that atrial dilatation or stretch may result in atrial fibrillation.
Autor:
Jie Lin, Min Xia, Yiping Chen, Yusong He, Zhiwen Pan, Petra M.H. Eurlings, Yanting Zhou, Rongrong Wang, Jacques Barhanin, Saïd Bendahhou, Li Li, Qinshu Zhou, Yi-Han Chen, Marie-Madeleine Larroque, Ban Liu, Qian Zhu, Weiqin Qiu, Qingfeng Jin, Xiongjian Dong, Haiying Wan, Yi Liu, Bo Liang, Wenyuan Xu, Yiqing Yang
Publikováno v:
Biochemical and Biophysical Research Communications. 332:1012-1019
The inward rectifier K(+) channel Kir2.1 mediates the potassium I(K1) current in the heart. It is encoded by KCNJ2 gene that has been linked to Andersen's syndrome. Recently, strong evidences showed that Kir2.1 channels were associated with mouse atr
Autor:
Cui-Mei Zhao, Lei Liang, Yi Liu, Yi-Han Chen, Qin Pan, Jun Li, Pengjuan Li, Qinshu Zhou, Zhimin Zhang, Luying Peng, Jie Qi, Yusong He
Publikováno v:
International Journal of Cardiology. 127:427-429
Atrial fibrillation (AF) is the most common arrhythmia in clinical practices. Mediated by muscarinic type 2 receptors (M(2)Rs), acetylcholine affects electrophysiological activities of atrial myocytes and may contribute to the onset of AF. In order t
Autor:
Yong-qing Tang, Wenjun Xu, Yongchao Liu, Jianmin Ma, Dandan Liang, Qinshu Zhou, YH Chen, Yang Yang, Jie Zhang, Pengjuan Li, Luying Peng, Junjie Xiao, Huaizhi Chen, Zhimin Zhang, Jieshou Li, Qin Pan
Publikováno v:
The Journal of international medical research. 37(2)
The left atrial posterior wall (LAPW) plays a critical role in atrial fibrillation, but the underlying mechanism remains unclear. In the present study, we sought to characterize the histological features of the LAPW. Different atrial regions were dis
Autor:
Qinshu Zhou, Qin Pan, Jie Lin, Yusong He, Xiaoping Lin, Zhiwen Pan, Yi Liu, Yiqing Yang, Ying Kuang, Xiaoyan Su, Petra M.H. Eurlings, Yi-Han Chen, Li Li, Zhugang Wang, Luying Peng, Ban Liu, Qingfeng Jin, Xiongjian Dong, Qian Zhu, Jian Fei
Publikováno v:
Heart rhythm. 4(5)
Background We recently reported that an S140G mutation in human KCNQ1, an alpha subunit of potassium channels, was involved in the pathogenesis of familial atrial fibrillation (AF), but it is not clear whether the mutation is associated with other ca
Autor:
Jie Lin, Jacques Barhanin, Qingfeng Jin, Dongwei Zhang, Zhaopeng Chen, Haiying Wan, Ning Ma, Qinshu Zhou, Yiping Chen, Jingyi Shi, Yan Pei, Ban Liu, Saïd Bendahhou, Yiqing Yang, Xiaoyan Su, Min Xia, Kaiya Niu, Yi-Han Chen, Wenyuan Xu, Jianmin Cui, Rong Wang, Yi Liu, Bo Liang
Publikováno v:
The American Journal of Human Genetics. (5):899-905
Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice. We first reported an S140G mutation of KCNQ1, an alpha subunit of potassium channels, in one Chinese kindred with AF. However, the molecular defects and
Autor:
Ramon Brugada, Kui Hong, Huaizhi Chen, Jun Li, Pedro Brugada, Yusong He, Qinshu Zhou, Yi-Han Chen, Guillermo J. Pérez, Qin Pan
Publikováno v:
FEBS Letters. (15):2338-2342
Inward rectifier potassium Kir2.x channels mediate cardiac inward rectifier potassium currents (IK1). As a subunit of Kir2.x, the physiological role of Kir2.3 in native cardiomyo- cytes has not been reported. This study shows that Kir2.3 knock-down r