Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Qinru Lin"'
Autor:
Xinyi Yang, Xu Zheng, Yuqi Zhu, Xiaying Zhao, Jun Liu, Jiangna Xun, Songhua Yuan, Jun Chen, Hanyu Pan, Jinlong Yang, Jing Wang, Zhimin Liang, Xiaoting Shen, Yue Liang, Qinru Lin, Huitong Liang, Min Li, Fei Peng, Daru Lu, Jianqing Xu, Hongzhou Lu, Shibo Jiang, Ping Zhao, Huanzhang Zhu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes multi-organ damage, which includes hepatic dysfunction, as observed in over 50% of COVID-19 patients. Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2) is th
Externí odkaz:
https://doaj.org/article/328ac007c7894de5abb7b72a389413cd
Autor:
Xinyi Yang, Xiaying Zhao, Yuqi Zhu, Jingna Xun, Qin Wen, Hanyu Pan, Jinlong Yang, Jing Wang, Zhimin Liang, Xiaoting Shen, Yue Liang, Qinru Lin, Huitong Liang, Min Li, Jun Chen, Shibo Jiang, Jianqing Xu, Hongzhou Lu, Huanzhang Zhu
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2785-2799 (2022)
Acquired immunodeficiency syndrome (AIDS) cannot be completely cured, mainly due to the existence of a latent HIV-1 reservoir. However, our current understanding of the molecular mechanisms underlying the establishment and maintenance of HIV-1 latent
Externí odkaz:
https://doaj.org/article/d5b603f802fa4313b266c253125b1ec6
Autor:
Xinyi Yang, Yuqi Zhu, Jingna Xun, Jun Liu, Qing Wen, Yixiao Lin, Xiaoting Shen, Jun Chen, Songhua Yuan, Xiaying Zhao, Jing Wang, Hanyu Pan, Jinlong Yang, Zhiming Liang, Yue Liang, Qinru Lin, Huitong Liang, Chunyan Zhou, Li Jin, Weijian Xie, Jianping Liu, Daru Lu, Tianlei Ying, Yinzhong Shen, Xiaoyan Zhang, Jianqing Xu, Chunhua Yin, Pengfei Wang, Shibo Jiang, Hongzhou Lu, Huanzhang Zhu
Publikováno v:
iScience, Vol 25, Iss 9, Pp 105016- (2022)
Summary: The SARS-CoV-2 variants B.1.617.1 (Kappa) contain multiple mutations in the spike protein. However, the effect of B.1.617.1 lineage-related mutants on viral infectivity and inactivated-virus vaccine efficacy remains to be defined. We therefo
Externí odkaz:
https://doaj.org/article/f3812d9781a246a6b72530620a50ebae
Autor:
Xinyi Yang, Xiaying Zhao, Yuqi Zhu, Yinzhong Shen, Yanan Wang, Panpan Lu, Zhengtao Jiang, Hanyu Pan, Jinlong Yang, Jingna Xun, Lin Zhao, Jing Wang, Zhiming Liang, Xiaoting Shen, Yue Liang, Qinru Lin, Huitong Liang, Lu Jin, Dengji Zhang, Jun Liu, Bin Wang, Shibo Jiang, Jianqing Xu, Hao Wu, Hongzhou Lu, Huanzhang Zhu
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) cannot be completely eliminated because of existence of the latent HIV-1 reservoir. However, the facts of HIV-1 latency, including its establishment and maintenance, are incomplete. FKBP3, encoded
Externí odkaz:
https://doaj.org/article/a0946e0c9912490095a19784f1acaf6e
Autor:
Zhengtao Jiang, Huitong Liang, Hanyu Pan, Yue Liang, Hua Wang, Xinyi Yang, Panpan Lu, Xiao Zhang, Jinlong Yang, Dengji Zhang, Xiaoting Shen, Jing Wang, Zhiming Liang, Qinru Lin, Yanan Wang, Lin Zhao, Yangcheng Zhong, Hongzhou Lu, Huanzhang Zhu
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Adoptive cellular immunotherapy therapy using broadly neutralizing antibody-based chimeric antigen receptor-T cells (bNAb-based CAR-T) has shown great potency and safety for the functional cure of HIV. The efficacy of bNAb-based CAR-T cells could be
Externí odkaz:
https://doaj.org/article/c2a7c9abc57e4d5381c7b030ce89991c
Autor:
Hanyu Pan, Xinyi Yang, Jing Wang, Huitong Liang, Zhengtao Jiang, Lin Zhao, Yanan Wang, Zhiming Liang, Xiaoting Shen, Qinru Lin, Yue Liang, Jinglong Yang, Panpan Lu, Yuqi Zhu, Min Li, Pengfei Wang, Jianqing Xu, Hongzhou Lu, Huanzhang Zhu
Publikováno v:
Virologica Sinica. 38:285-295
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ffce72efb2e326c60c29fb9adc96de3
https://doi.org/10.1016/j.virs.2023.01.003
https://doi.org/10.1016/j.virs.2023.01.003
Autor:
Xiaoting Shen, Qinru Lin, Zhiming Liang, Jing Wang, Xinyi Yang, Yue Liang, Huitong Liang, Hanyu Pan, Jinlong Yang, Yuqi Zhu, Min Li, Weirong Xiang, Huanzhang Zhu
Publikováno v:
The CRISPR Journal. 5:445-456
The CRISPR-Cas9 system is increasingly being used as a gene editing therapeutic technique in complex diseases but concerns remain regarding the clinical risks of Cas9 immunogenicity. In this study, we detected antibodies against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e412e6194b464fd9f7d7c884825007d4
https://doi.org/10.1089/crispr.2021.0142
https://doi.org/10.1089/crispr.2021.0142
Autor:
Yuqi Zhu, Xinyi Yang, Jingna Xun, Jun Liu, Qing Wen, Yixiao Lin, Xiaoting Shen, Jun Chen, Songhua Yuan, Xiaying Zhao, Jing Wang, Hanyu Pan, Jinlong Yang, Zhiming Liang, Yue Liang, Qinru Lin, Huitong Liang, Min Li, Jianping Liu, Yinzhong Shen, Xiaoyan Zhang, Pengfei Wang, Daru Lu, Chunhua Yin, Jianqing Xu, Shibo Jiang, Hongzhou Lu, Huanzhang Zhu
Publikováno v:
Virologica Sinica. 37(6)
The prevalence of SARS-CoV-2 variants of concern (VOCs) is still escalating throughout the world. However, the level of neutralization of the inactivated viral vaccine recipients' sera and convalescent sera against all VOCs, including B.1.1.7 (Alpha)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32da43dc83887338adc8272d815c7695
https://pubmed.ncbi.nlm.nih.gov/36309305
https://pubmed.ncbi.nlm.nih.gov/36309305
Autor:
Xinyi Yang, Yuqi Zhu, Xiaying Zhao, Jun Liu, Jiangna Xun, Songhua Yuan, Jun Chen, Hanyu Pan, Jinlong Yang, Jing Wang, Zhimin Liang, Xiaoting Shen, Yue Liang, Qinru Lin, Huitong Liang, Min Li, Hongzhou Lu, Huanzhang Zhu
Backgroud & AimsCurrently, the COVID-19 pandemic, caused by SARS-CoV-2 infection, represents a serious public health problem worldwide. Although it has been shown that ACE2 serves as the main receptor for SARS-CoV-2 entry into host cells, studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06a488508145459ce6cd52179a472d14
https://doi.org/10.1101/2022.01.15.476426
https://doi.org/10.1101/2022.01.15.476426
Autor:
Hanyu Pan, Jing Wang, Huitong Liang, Zhengtao Jiang, Lin Zhao, Yanan Wang, Xinyi Yang, Zhiming Liang, Xiaoting Shen, Qinru Lin, Yue Liang, Jinglong Yang, Panpan Lu, Yuqi Zhu, Weirong Xiang, Min Li, Pengfei Wang, Huanzhang Zhu
HIV-specific chimeric antigen receptor (CAR) T cells have been developed to target latently infected CD4+ T cells that express virus either spontaneously or after intentional latency reversal. However, the T-cell exhaustion and the patient-specific a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5cfa3380ec2adcc764f4a9258c842da
https://doi.org/10.1101/2022.01.14.476413
https://doi.org/10.1101/2022.01.14.476413