Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Qinjun Wei"'
Autor:
Kun Huang, Jing Cai, Yajie Lu, Tianming Wang, Shen Yue, Qinjun Wei, Jun Yao, Zhibin Chen, Xin Cao
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e36140- (2024)
G protein-coupled receptor-associated sorting protein 2 (GPRASP2) deficiency has been implicated in immunological inflammation, cancers, and neurological disorders. Our previous work revealed that the pathogenic mutation in GPRASP2 was responsible fo
Externí odkaz:
https://doaj.org/article/239f24df8f8d46989ed69383d025b668
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-8 (2021)
Abstract Background Ultrasound examination can be applied to the diagnosis of pediatric elbow fracture. This study aims to analyze the application value of ultrasound in the surgical treatment of supracondylar humeral fractures. Methods 64 children w
Externí odkaz:
https://doaj.org/article/9fd9e70bab954cdb8e096fd63cb92412
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Niemann–Pick type C disease (NPCD) is a rare genetic syndrome characterized by cholesterol accumulation in multiple organelles. NPCD is mainly caused by gene deficiency of NPC intracellular cholesterol transporter 1 (NPC1). It has been reported tha
Externí odkaz:
https://doaj.org/article/49ac256f4c624edfa2af1a93c6bba3f5
Autor:
Tianming Wang, Tianyu Zhang, Youzhi Tang, Hongshun Wang, Qinjun Wei, Yajie Lu, Jun Yao, Yuan Qu, Xin Cao
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-16 (2021)
Abstract Oxysterol-binding protein-like 2 (OSBPL2), also known as oxysterol-binding protein-related protein (ORP) 2, is a member of lipid transfer protein well-known for its role in regulating cholesterol homeostasis. A recent study reported that OSB
Externí odkaz:
https://doaj.org/article/fd5fd2fc1a844cc799eb9c35fb808d67
Autor:
Hairong Shi, Hongshun Wang, Cheng Zhang, Yajie Lu, Jun Yao, Zhibin Chen, Guangqian Xing, Qinjun Wei, Xin Cao
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
Defective primary cilia cause a range of diseases called ciliopathies, which include hearing loss (HL). Variants in the human oxysterol-binding protein like 2 (OSBPL2/ORP2) are responsible for autosomal dominant nonsyndromic HL (DFNA67). However, the
Externí odkaz:
https://doaj.org/article/a76238c501cb4fcbb1d643656cd09ca0
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1217 (2022)
Lipid transporter protein apolipoprotein E (APOE) has contributed to functional studies of various organ functions. Animals with ApoE knockout (KO) have been used to study atherosclerosis and hyperlipidemia while an increasing number of researchers h
Externí odkaz:
https://doaj.org/article/75fff5dc7e304d9b91d2e9a2cc438089
Autor:
Tianming Wang, Qinjun Wei, Lihong Liang, Xujun Tang, Jun Yao, Yajie Lu, Yuan Qu, Zhibin Chen, Guangqian Xing, Xin Cao
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101252- (2020)
Summary: The accumulation of giant lipid droplets (LDs) increases the risk of metabolic disorders including obesity and insulin resistance. The lipolysis process involves the activation and transfer of lipase, but the molecular mechanism is not compl
Externí odkaz:
https://doaj.org/article/498fd2ce4bed42138dc7de0ccb5c45bb
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-8 (2021)
Journal of Orthopaedic Surgery and Research
Journal of Orthopaedic Surgery and Research
Background Ultrasound examination can be applied to the diagnosis of pediatric elbow fracture. This study aims to analyze the application value of ultrasound in the surgical treatment of supracondylar humeral fractures. Methods 64 children with supra
Autor:
Qinjun Wei, Jun Yao, Youzhi Tang, Yajie Lu, Hongshun Wang, Tianming Wang, Xin Cao, Tianyu Zhang, Yuan Qu
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-16 (2021)
Cell Death Discovery
Cell Death Discovery
Oxysterol-binding protein-like 2 (OSBPL2), also known as oxysterol-binding protein-related protein (ORP) 2, is a member of lipid transfer protein well-known for its role in regulating cholesterol homeostasis. A recent study reported that OSBPL2/ORP2
Publikováno v:
Biochemical and Biophysical Research Communications. 521:42-49
In our previous study, Oxysterol-binding protein-related protein 2 (OSBPL2) was first identified as a new deafness-causative gene contribute to non-syndromic hearing loss. However, the underlying mechanism of OSBPL2-induced hearing loss remains unkno