Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Qini Gan"'
Autor:
Qini Gan, Alfred Wong, Zhengrong Zhang, Hana Na, Hua Tian, Qiushan Tao, Ibraheem M. Rajab, Lawrence A. Potempa, Wei Qiao Qiu
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Human study shows that elevated C‐reactive protein (CRP) in blood impacts apolipoprotein E (APOE) ε4, but not APOE ε3 or APOE ε2, genotype to increase the risk of Alzheimer's disease (AD). However, whether CRP is directly i
Externí odkaz:
https://doaj.org/article/ecd935561cd14358a3dd11dbce9a2898
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1710 (2008)
Sir2, a NAD-dependent deacetylase, modulates lifespan in yeasts, worms and flies. The SIRT1, mammalian homologue of Sir2, regulates signaling for favoring survival in stress. But whether SIRT1 has the function to influence cell viability and senescen
Externí odkaz:
https://doaj.org/article/bb460204c274409eb19873d68e230f11
Autor:
Hana Na, Jack B. Yang, Zhengrong Zhang, Qini Gan, Hua Tian, Ibraheem M. Rajab, Lawrence A. Potempa, Qiushan Tao, Wei Qiao Qiu
Publikováno v:
Neurobiology of Aging. 127:54-69
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d63cfc31820397d496ec7ae83d749b1
https://doi.org/10.1016/j.neurobiolaging.2023.02.013
https://doi.org/10.1016/j.neurobiolaging.2023.02.013
Autor:
Jiani Bei, Ernesto G. Miranda-Morales, Qini Gan, Yuan Qiu, Sorosh Husseinzadeh, Jia Yi Liew, Qing Chang, Balaji Krishnan, Angelo Gaitas, Subo Yuan, Michelle Felicella, Wei Qiao Qiu, Xiang Fang, Bin Gong
Publikováno v:
bioRxiv
BackgroundBlood-brain barrier (BBB) breakdown is a component of the progression and pathology of Alzheimer’s disease (AD). BBB dysfunction is primarily caused by reduced or disorganized tight junction or adherens junction proteins of brain microvas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b73487e50f3493da00e4164425a83c4
https://europepmc.org/articles/PMC10103966/
https://europepmc.org/articles/PMC10103966/
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. :0271678X2311700
Several studies have shown that an abnormal vascular-immunity link could increase Alzheimer’s disease (AD) risk; however, the mechanism is unclear. CD31, also named platelet endothelial cell adhesion molecule (PECAM), is a surface membrane protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::221753bcc888a614418cb007dfbfcbc6
https://doi.org/10.1177/0271678x231170041
https://doi.org/10.1177/0271678x231170041
Autor:
Ibraheem M. Rajab, Thor D. Stein, Benjamin Wolozin, Xiaoling Zhang, Lawrence A. Potempa, Hana Na, Jack B. Yang, Qiushan Tao, Qiang Li, Wei Qiao Qiu, Zhengrong Zhang, Junming Hu, Jan Krizysztof Blusztajn, Qini Gan, Yuriy O. Alekseyev, Shenyu Zhu, Andrew Emili, Zili Yan, Hua Tian
Publikováno v:
Aging Cell
In chronic peripheral inflammation, endothelia in brain capillary beds could play a role for the apolipoprotein E4 (ApoE4)‐mediated risk for Alzheimer's disease (AD) risk. Using human brain tissues, here we demonstrate that the interactions of endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c37d90a7444c959b82e36537855f4cf
https://doi.org/10.1111/acel.13501
https://doi.org/10.1111/acel.13501
Autor:
Shengxi Wu, YiPing Chen, Salaheddin Hamad, Takashi Yamagami, David E Pleasure, Hirohide Takebayashi, Norihisa Bizen, Tianyu Zhao, Qini Gan, Ran Gu, Ya Zhou Wang, Kurt Reynolds, Yu Ji, Hong Fan, Chengji J. Zhou, Kit S. Lam
Publikováno v:
Cell Mol Life Sci
Cellular and molecular life sciences : CMLS, vol 77, iss 18
Cellular and molecular life sciences : CMLS, vol 77, iss 18
The bHLH transcription factor Olig2 is required for sequential cell fate determination of both motor neurons and oligodendrocytes and for progenitor proliferation in the central nervous system. However, the role of Olig2 in peripheral sensory neuroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a04179e122e47101203ec90781c8f2
https://doi.org/10.1007/s00018-019-03385-x
https://doi.org/10.1007/s00018-019-03385-x
Autor:
Qiushan Tao, Qini Gan, Wei Qiao Qiu, Hongbo Yao, Hua Tian, Lorene Leung, Heather I. Ballance, Haihao Zhu, Hana Na, Benjamin Wolozin
Publikováno v:
Journal of Alzheimer's Disease. 70:1025-1040
Recent studies demonstrate that peripheral amylin treatment reduces pathology in mouse models of Alzheimer's disease (AD). However, soluble and aggregated amylin are distinct species; while amylin is a physiological neuropeptide, amylin aggregation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9dddb130e69a39d14c0a5d32222702
https://doi.org/10.3233/jad-190161
https://doi.org/10.3233/jad-190161
Autor:
Anilkumar Pillai, Nicole R. DeTore, Kim T. Mueser, Qini Gan, Susan R. McGurk, Wei Qiao Qiu, Sai Snigdha Talluri, Daniel Fulford, Michael W. Otto, Ivy Tran, Laura H. Turner, Chitra Khare, Zachary Cutler, Stacey A. Zawacki, Leonard P. Mulcahy
Publikováno v:
Journal of psychiatric research. 139
Background Preliminary evidence suggests that aerobic exercise may augment the effects of cognitive remediation on improving cognitive functioning in severe mental illness. It has also been hypothesized that increases in cognitive functioning associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08f79778397b06a6b6607657a66eb12
https://pubmed.ncbi.nlm.nih.gov/34022474
https://pubmed.ncbi.nlm.nih.gov/34022474
Autor:
Ran Gu, Chengji J. Zhou, Ya Zhou Wang, YiPing Chen, Norihisa Bizen, Hong Fan, Qini Gan, Salaheddin Hamad, Takashi Yamagami, Kit S. Lam, Shengxi Wu, Kurt Reynolds, Yu Ji, Tianyu Zhao, Hirohide Takebayashi, David E Pleasure
Publikováno v:
Cellular and Molecular Life Sciences. 78:5665-5666
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e9837e1df69a838ba565e8e36c89394
https://doi.org/10.1007/s00018-021-03870-2
https://doi.org/10.1007/s00018-021-03870-2