Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Qingzhi Shi"'
Autor:
Zhongjun Xia, Yun Leng, Baijun Fang, Yang Liang, Wei Li, Chengcheng Fu, Linhua Yang, Xiaoyan Ke, Hua Jiang, Jianyu Weng, Li Liu, Yaozhong Zhao, Xuejun Zhang, Zhongxia Huang, Aichun Liu, Qingzhi Shi, Yuhuan Gao, Xiequn Chen, Ling Pan, Zhen Cai, Zhao Wang, Yafei Wang, Yaqun Fan, Ming Hou, Yigai Ma, Jianda Hu, Jing Liu, Jianfeng Zhou, Xiaohong Zhang, Haitao Meng, Xuzhang Lu, Fei Li, Hanyun Ren, Bintao Huang, Zonghong Shao, Hebing Zhou, Yu Hu, Shifang Yang, Xiangjun Zheng, Peng Wei, Hongyan Pang, Wei Yu, Yuzhang Liu, Sujun Gao, Lingzhi Yan, Yanping Ma, Hongmei Jing, Juan Du, Wei Ling, Jingyi Zhang, Weiwei Sui, Fuxu Wang, Xin Li, Wenming Chen
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Aponermin, a circularly permuted tumor necrosis factor-related apoptosis-inducing ligand, is a potential death receptor 4/5-targeted antitumour candidate. Previous phase 1/2 studies have demonstrated the efficacy of aponermin in p
Externí odkaz:
https://doaj.org/article/b54d9a34e0c7454a9a0589390ee8abee
Autor:
Heng Mei, Xiaofan Liu, Yan Li, Hu Zhou, Ying Feng, Guangxun Gao, Peng Cheng, Ruibin Huang, Linhua Yang, Jianda Hu, Ming Hou, Yazhou Yao, Li Liu, Yi Wang, Depei Wu, Liansheng Zhang, Changcheng Zheng, Xuliang Shen, Qi Hu, Jing Liu, Jie Jin, Jianmin Luo, Yun Zeng, Sujun Gao, Xiaohui Zhang, Xin Zhou, Qingzhi Shi, Ruixiang Xia, Xiaobao Xie, Zhongxing Jiang, Li Gao, Yuansong Bai, Junye Xiong, Runzi Li, Jianjun Zou, Ting Niu, Renchi Yang, Yu Hu
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-14 (2021)
Abstract Background Hetrombopag, a novel thrombopoietin receptor agonist, has been found in phase I studies to increase platelet counts and reduce bleeding risks in adults with immune thrombocytopenia (ITP). This phase III study aimed to evaluate the
Externí odkaz:
https://doaj.org/article/05d1c73f724f4026bed75405ee45731e
Autor:
Heng Mei, Xiaofan Liu, Yan Li, Hu Zhou, Ying Feng, Guangxun Gao, Peng Cheng, Ruibin Huang, Linhua Yang, Jianda Hu, Ming Hou, Yazhou Yao, Li Liu, Yi Wang, Depei Wu, Liansheng Zhang, Changcheng Zheng, Xuliang Shen, Qi Hu, Jing Liu, Jie Jin, Jianmin Luo, Yun Zeng, Sujun Gao, Xiaohui Zhang, Xin Zhou, Qingzhi Shi, Ruixiang Xia, Xiaobao Xie, Zhongxing Jiang, Li Gao, Yuansong Bai, Junye Xiong, Runzi Li, Jianjun Zou, Ting Niu, Renchi Yang, Yu Hu
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:716-728
Background The efficacy of hetrombopag in Chinese patients with immune thrombocytopenia (ITP) has been demonstrated in a randomized, double-blind, placebo-controlled, multicenter, phase III trial (NCT03222843). Objective This study aimed to report co
Publikováno v:
Vacuum. 213:112096
Autor:
Hu Zhou, Jianfeng Zhou, Depei Wu, Liping Ma, Xin Du, Ting Niu, Renchi Yang, Jing Liu, Feng Zhang, Qingzhi Shi, Xiuli Wang, Hongmei Jing, Junmin Li, Xin Wang, Zhongguang Cui, Zeping Zhou, Ming Hou, Zonghong Shao, Jie Jin, Wenqian Li, Hanyun Ren, Jianda Hu, Jianliang Shen, Li Liu, Yun Zeng, Jin Zhou, Xin Liu, Yunfeng Shen, Kai Ding, Tadaaki Taira, Huacong Cai, Yongqiang Zhao
Publikováno v:
Research and Practice in Thrombosis and Haemostasis. :100192
Autor:
Mei, Heng, Xiaofan Liu, Li, Yan, Zhou, Hu, Feng, Ying, Guangxun Gao, Cheng, Peng, Ruibin Huang, Linhua Yang, Jianda Hu, Hou, Ming, Yazhou Yao, Liu, Li, Wang, Yi, Depei Wu, Liansheng Zhang, Changcheng Zheng, Xuliang Shen, Hu, Qi, Liu, Jing, Jin, Jie, Jianmin Luo, Zeng, Yun, Sujun Gao, Xiaohui Zhang, Zhou, Xin, Qingzhi Shi, Ruixiang Xia, Xiaobao Xie, Zhongxing Jiang, Gao, Li, Yuansong Bai, Junye Xiong, Runzi Li, Jianjun Zou, Niu, Ting, Renchi Yang, Hu, Yu
Additional file 1: Table S1. Investigators per site. Table S2. Dose adjustments of hetrombopag during the double-blind treatment period and open-label treatment period. Table S3. Dose adjustments of eltrombopag for patients in the Placebo-eltrombopag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024dc27e51b49a63986b340057781ca4
Autor:
Heng, Mei, Xiequn, Chen, Jianfeng, Zhou, Jianmin, Luo, Qingzhi, Shi, Jing, Liu, Depei, Wu, Guoan, Chen, Yanfei, Tai, Junye, Xiong, Jianjun, Zou, Yu, Hu
Publikováno v:
Ann Transl Med
BACKGROUND: Thrombopoietin receptor agonists (TPO‐RAs) are promising therapeutic strategy for patients with immune thrombocytopenia (ITP). We conducted this phase 1 trial (NCT02614846) to evaluate the preliminary efficacy and safety of hetrombopag
Autor:
Zhongjun Xia, Qingzhi Shi, Shifang Yang, Wenming Chen, Zhao Wang, L H Yang, Hua Jiang, Jianyu Weng, Yafei Wang, Xiaoyan Ke, Aichun Liu, Yaozhong Zhao, Zhongxia Huang, Xuejun Zhang, Xiequn Chen, Yizhuo Zhang, Li Liu, Ling Pan, Wei Li, Baijun Fang, Yaqun fan, Zhen Cai, Ming Hou, Yuhuan Gao, Chengcheng Fu
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S143
Background CPT, a recombinant permuted human TNF-related apoptosis-inducing ligand (TRAIL), is a 1rst-in-human anti-myeloma drug targeting death receptor 4/5. In order to verify the effectiveness and safety of CPT, we have conducted this multi-center
Publikováno v:
Oncology Letters
Metformin is a standard clinical drug used to treat type 2 diabetes mellitus (T2DM) and polycystic ovary syndrome. Recently, epidemiological studies and meta-analyses have revealed that patients with T2DM have a lower incidence of tumor development t
Publikováno v:
Oncology reports. 42(6)
B-cell receptor (BCR) signaling is important for the development and maturation of normal B-cells and plays a key role in B-cell malignancies. Bruton's tyrosine kinase (BTK), a crucial terminal kinase enzyme in BCR signaling, has emerged as an attrac