Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Qingzhen Yu"'
Autor:
Tuo Shao, Zhen Chen, Jian Rong, Vasily Belov, Jiahui Chen, Andre Jeyarajan, Xiaoyun Deng, Hualong Fu, Qingzhen Yu, Steve H. Rwema, Wenyu Lin, Mikhail Papisov, Lee Josephson, Raymond T. Chung, Steven H. Liang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 308-315 (2022)
Monoacylglycerol lipase (MAGL) is a pivotal enzyme in the endocannabinoid system, which metabolizes 2-arachidonoylglycerol (2-AG) into the proinflammatory eicosanoid precursor arachidonic acid (AA). MAGL and other endogenous cannabinoid (EC) degradin
Externí odkaz:
https://doaj.org/article/8eeb1fa8620445a3995e56ae5f3595fe
Autor:
Wenli Mao, Qingzhen Yu, Kefeng Wang, Qiang Ma, Yuxin Zheng, Guojun Zhang, Wei Luo, Nianwu Wang, Yukun Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/e619063278cf48098368090f79c10a02
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104977- (2022)
Summary: Vinylboron compounds are important compounds in organic chemistry and biology. In this communication, we developed a copper(I)-catalyzed, highly regio- and stereoselective radical trans-hydroboration of ynamides with N-heterocyclic carbene (
Externí odkaz:
https://doaj.org/article/f635bcdd0bbc4535b7fd5d85a3b0d82f
Autor:
Zhen Chen, Wakana Mori, Jian Rong, Michael A. Schafroth, Tuo Shao, Richard S. Van, Daisuke Ogasawara, Tomoteru Yamasaki, Atsuto Hiraishi, Akiko Hatori, Jiahui Chen, Yiding Zhang, Kuan Hu, Masayuki Fujinaga, Jiyun Sun, Qingzhen Yu, Thomas L. Collier, Yihan Shao, Benjamin F. Cravatt, Lee Josephson, Ming-Rong Zhang, Steven H. Liang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1686-1695 (2021)
As a serine hydrolase, monoacylglycerol lipase (MAGL) is principally responsible for the metabolism of 2-arachidonoylglycerol (2-AG) in the central nervous system (CNS), leading to the formation of arachidonic acid (AA). Dysfunction of MAGL has been
Externí odkaz:
https://doaj.org/article/6647b3af1e7f460aab63220f173d99be
Autor:
Wenli Mao, Qingzhen Yu, Kefeng Wang, Qiang Ma, Yuxin Zheng, Guojun Zhang, Wei Luo, Nianwu Wang, Yukun Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
N6-methyladenosine (m6A) is the most abundant internal modification on eukaryotic mRNAs. There is increasing evidence that m6A plays a key role in tumor progression, so it is important to analyze m6A modifications within the transcriptome-wide in lun
Externí odkaz:
https://doaj.org/article/f7e90d155ffc476db9182f2f8f0908e1
Autor:
Qingzhen, Yu, Katsushi, Kumata, Jian, Rong, Zhen, Chen, Tomoteru, Yamasaki, Jiahui, Chen, Zhiwei, Xiao, Hideki, Ishii, Atsuto, Hiraishi, Tuo, Shao, Zhang, Yiding, Kuan, Hu, Lin, Xie, Masayuki, Fujinaga, Chunyu, Zhao, Wakana, Mori, Thomas, Collier, Ahmed, Haider, Susumu, Tomita, Zhang, Ming-Rong, Steven, Liang
Publikováno v:
Journal of Medicinal Chemistry. 65(13):9144-9158
The transmembrane α-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid (AMPA) receptor regulatory protein γ-8 (TARP γ-8) constitutes an auxiliary subunit of AMPA receptors, which mediates various brain functions including learning and memory. TAR
Autor:
Wenyu Lin, Qingzhen Yu, Tuo Shao, Mikhail Papisov, Andre J Jeyarajan, Jiahui Chen, Jian Rong, Zhen Chen, Lee Josephson, Steven H. Liang, Steve Rwema, Vasily Belov, Xiaoyun Deng, Raymond T. Chung, Hualong Fu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 308-315 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Monoacylglycerol lipase (MAGL) is a pivotal enzyme in the endocannabinoid system, which metabolizes 2-arachidonoylglycerol (2-AG) into the proinflammatory eicosanoid precursor arachidonic acid (AA). MAGL and other endogenous cannabinoid (EC) degradin
Autor:
Yiding Zhang, Jiahui Chen, Atsuto Hiraishi, Steven H. Liang, Tomoteru Yamasaki, Ming-Rong Zhang, Benjamin F. Cravatt, Wakana Mori, Lee Josephson, Richard Van, Jian Rong, Tuo Shao, Masayuki Fujinaga, Michael A. Schafroth, Akiko Hatori, Thomas Lee Collier, Jiyun Sun, Qingzhen Yu, Kuan Hu, Zhen Chen, Yihan Shao, Daisuke Ogasawara
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1686-1695 (2021)
As a serine hydrolase, monoacylglycerol lipase (MAGL) is principally responsible for the metabolism of 2-arachidonoylglycerol (2-AG) in the central nervous system (CNS), leading to the formation of arachidonic acid (AA). Dysfunction of MAGL has been
Publikováno v:
Journal of clinical pharmacology.
This systematic review and meta-analysis aimed to reveal the efficacy and safety of zoledronic acid compared with alendronate in patients with primary osteoporosis. The PubMed, Embase, and the Cochrane Library databases were searched from the establi
Publikováno v:
iScience. 25(9)
Vinylboron compounds are important compounds in organic chemistry and biology. In this communication, we developed a copper(I)-catalyzed, highly regio- and stereoselective radical