Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Qingzhang Li"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14352 (2023)
The mammary gland undergoes intensive remodeling during the lactation cycle, and the involution process of mammary gland contains extensive epithelial cells involved in the process of autophagy. Our studies of mice mammary glands suggest that miR-30a
Externí odkaz:
https://doaj.org/article/401f84b5523342db855fd57fa0c91e52
Autor:
Yingjun Cui, Xia Sun, Lianfeng Jin, Guangpu Yu, Qingzhang Li, Xuejun Gao, Jinxia Ao, Chunmei Wang
Publikováno v:
BMC Veterinary Research, Vol 13, Iss 1, Pp 1-10 (2017)
Abstract Background MicroRNAs have important roles in many biological processes. However, the role of miR-139 in healthy mammary gland remains unclear. The objective of this study was to investigate the effects of miR-139 on lactation in dairy cows.
Externí odkaz:
https://doaj.org/article/c000e9b933594759aba399dc74bd4a24
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 7, Pp 16622-16641 (2015)
As a protective factor for lipopolysaccharide (LPS)-induced injury, 14-3-3γ has been the subject of recent research. Nevertheless, whether 14-3-3γ can regulate lactation in dairy cow mammary epithelial cells (DCMECs) induced by LPS remains unknown.
Externí odkaz:
https://doaj.org/article/2bc293e233544d799614b75fdcaae49c
Autor:
Xia Zhang, Feng Zhao, Yu Si, Yuling Huang, Cuiping Yu, Chaochao Luo, Na Zhang, Qingzhang Li, Xuejun Gao
Publikováno v:
Molecules, Vol 19, Iss 7, Pp 9435-9452 (2014)
Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase, whose activity is inhibited by AKT phosphorylation. This inhibitory phosphorylation of GSK3β can in turn play a regulatory role through phosphorylation of several proteins (such as mTOR
Externí odkaz:
https://doaj.org/article/32c9ab1ea3fb4b8b8bb002d1c1dec83b
Autor:
Lina Wang, Ye Lin, Yanjie Bian, Lili Liu, Li Shao, Lin Lin, Bo Qu, Feng Zhao, Xuejun Gao, Qingzhang Li
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 4, Pp 5952-5969 (2014)
The role of LeuRS, an aminoacyl-tRNA synthetase, as an intracellular l-leucine sensor for the mTORC1 pathway has been the subject of much research recently. Despite this, the association between LeuRS and lactation in dairy cow mammary epithelial cel
Externí odkaz:
https://doaj.org/article/e6da2b77b3b04b199a3c162b5cca01ba
Autor:
Qingzhang Li, Yingjun Cui
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 2, Pp 4094-4105 (2013)
Fibroblast growth factor 10 (FGF10) is important as a mesenchymal mediator of epithelial growth and morphogenesis. In this study, the expression and localization of the FGF10 protein were detected by laser scanning confocal microscopy during mouse po
Externí odkaz:
https://doaj.org/article/f5b775a025af4efb8d318879b79a5427
Publikováno v:
Slovenian Veterinary Research, Vol 53, Iss 3 (2016)
Estrogen and prolactin can regulate mammary gland development and epithelial cell growth as well as lactation. Meanwhile, the Wnt signaling pathway and subsequent upregulation of b-catenin driven by downstream target of cyclinD1 also play a role in d
Externí odkaz:
https://doaj.org/article/5a87cf68723d444191f7b2d103eac4e4
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118284 (2015)
Mammary gland development is controlled by several genes. Although miRNAs have been implicated in mammary gland function, the mechanism by which miR-486 regulates mammary gland development and lactation remains unclear. We investigated miR-486 expres
Externí odkaz:
https://doaj.org/article/f6d4305922654c259e7662787bbce920
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101358 (2014)
MicroRNAs (miRNAs) are a class of small non-coding, endogenous regulatory RNAs that function by controlling gene expression at the post-transcriptional level. Using small RNA sequencing and qRT-PCR techniques, we found that the expression of miR-152
Externí odkaz:
https://doaj.org/article/8b78c1f2f7434c0aa0dbc6696d72b044
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102118 (2014)
Pten is a tumor suppressor gene regulating many cellular processes, including growth, adhesion, and apoptosis. In the aim of investigating the role of Pten during mammary gland development and lactation of dairy cows, we analyzed Pten expression leve
Externí odkaz:
https://doaj.org/article/a0bf0af3bb134badba1a81237672dc2b