Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Qingyun J. Liu"'
Autor:
Jianghua Tu, Yukimatsu Toh, Adela M. Aldana, Jake J. Wen, Ling Wu, Joan Jacob, Li Li, Sheng Pan, Kendra S. Carmon, Qingyun J. Liu
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 943 (2024)
Neuroblastoma (NB) is a cancer of the peripheral nervous system found in children under 15 years of age. It is the most frequently diagnosed cancer during infancy, accounting for ~12% of all cancer-related deaths in children. Leucine-rich repeat-cont
Externí odkaz:
https://doaj.org/article/b554555fbb0e479498a913ebf4b4a194
Autor:
Yukimatsu Toh, Ling Wu, Soohyun Park, Allison Wang, Jianghua Tu, Wangsheng Yu, Mingxin Zuo, Kendra S. Carmon, Qingyun J. Liu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract LGR4 and LGR5 are two homologous receptors that potentiate Wnt/β-catenin signaling in response to R-spondin (RSPO) ligands. The RSPO and LGR4 complex binds to and inhibits activities of two related E3 ubiquitin ligases, RNF43 and ZNRF3, and
Externí odkaz:
https://doaj.org/article/bac99d20d61a474cb90d937a87d04cd9
Autor:
Joan Jacob, Liezl E. Francisco, Treena Chatterjee, Zhengdong Liang, Shraddha Subramanian, Qingyun J. Liu, Julie H. Rowe, Kendra S. Carmon
Publikováno v:
British Journal of Cancer. 128:1592-1602
Antibody-drug conjugates (ADCs) have become an increasingly successful class of anticancer therapy, particularly within the past few years. Though ADCs are in clinical trials for colorectal cancer (CRC), a candidate has yet to be approved. CRC contin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c31f42f7ee8312cf625cca3bc318d77
https://doi.org/10.1038/s41416-023-02192-3
https://doi.org/10.1038/s41416-023-02192-3
Figure S1. Effects of loss of LGR5 on GPR56 expression in colon cancer cells. Figure S2. Effects of GPR56 levels on colon cancer cell proliferation, drug resistance, and ABC transporter expression Figure S3. Changes in MDR1 levels and function in col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1daff1d35957859ea5cfa1c2311ea0
https://doi.org/10.1158/1541-7786.22515985
https://doi.org/10.1158/1541-7786.22515985
Drug resistance continues to be a major obstacle of effective therapy for colorectal cancer, leading to tumor relapse or treatment failure. Cancer stem cells (CSC) or tumor-initiating cells are a subpopulation of tumor cells which retain the capacity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39a07a5c8eaf3f12d075e073f758b661
https://doi.org/10.1158/1541-7786.c.6541237
https://doi.org/10.1158/1541-7786.c.6541237
Methods pertaining to experiments included in supplement and not described in manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96aed8ce9f55c09330280632e2ef6a7
https://doi.org/10.1158/1541-7786.22515982
https://doi.org/10.1158/1541-7786.22515982
Autor:
Soohyun Park1, Jie Cui2, Wangsheng Yu1, Ling Wu1, Carmon, Kendra S.1, Qingyun J. Liu1 Qingyun.liu@uth.tmc.edu
Publikováno v:
Journal of Biological Chemistry. 6/22/2018, Vol. 293 Issue 25, p9759-9769. 11p.