Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Qingyu, Ruan"'
Autor:
Xiyuan Yu, Weidong Ruan, Fanghe Lin, Weizhou Qian, Yuan Zou, Yilong Liu, Rui Su, Qi Niu, Qingyu Ruan, Wei Lin, Zhi Zhu, Huimin Zhang, Chaoyong Yang
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Single-cell copy number variations (CNVs), major dynamic changes in humans, result in differential levels of gene expression and account for adaptive traits or underlying disease. Single-cell sequencing is needed to reveal these CNVs but has been hin
Autor:
Qingyu Ruan, Jian Yang, Fenxiang Zou, Xiaofeng Chen, Qianqian Zhang, Kaifeng Zhao, Xiaoye Lin, Xi Zeng, Xiyuan Yu, Lingling Wu, Shuichao Lin, Zhi Zhu, Chaoyong Yang
Publikováno v:
Analytical Chemistry. 94:1108-1117
Gene mutation profiling of heterogeneous circulating tumor cells (CTCs) offers comprehensive and real-time molecular information of tumors for targeted therapy guidance, but the lack of efficient and multiplex genotyping techniques for single-CTC ana
Autor:
Xing Xu, Fenxiang Zou, Tian Tian, Chaoyong Yang, Leiji Zhou, Huimin Zhang, Xiaoye Lin, Qingyu Ruan, Yang Wang, Yingkun Zhang, Zhi Zhu
Publikováno v:
ACS Applied Materials & Interfaces. 13:8042-8048
Biomarkers based on DNA methylation have attracted wide attention in biomedical research due to their potential clinical value. Therefore, a sensitive and accurate method for DNA methylation detection is highly desirable for the discovery and diagnos
Publikováno v:
Nanotechnology and Microfluidics
Autor:
Tingyu Li, Jacques Nsabimana, Qingyu Ruan, Yang Wang, Chaoyong James Yang, Zhi Zhu, Haicong Shen
Publikováno v:
The Analyst. 146(14)
Electrochemical detection is the simplest analytical tool to be integrated into digital microfluidics (DMF). It offers the advantages of small size, with detector electrodes incorporated into the device by patterning, and high compatibility with port
Autor:
Chaoyong Yang, Qingyu Ruan, Xiaoye Lin, Leiji Zhou, Zhi Zhu, Yang Wang, Weidong Ruan, Fenxiang Zou
Publikováno v:
Science Advances
Digital-WGS enables high-performance single-cell sequencing with automatic processing based on digital microfluidics.
Single-cell whole-genome sequencing (WGS) is critical for characterizing dynamic intercellular changes in DNA. Current sample p
Single-cell whole-genome sequencing (WGS) is critical for characterizing dynamic intercellular changes in DNA. Current sample p
Autor:
Chaoyong Yang, Linfeng Cai, Xi Zeng, Qingyu Ruan, Xuanqun Wang, Lingling Wu, Jia Song, Yingwen Chen
Publikováno v:
Small Methods. 5:2170024
Autor:
Jia Song, Xuanqun Wang, Chaoyong Yang, Lingling Wu, Xi Zeng, Linfeng Cai, Qingyu Ruan, Yingwen Chen
Publikováno v:
Small Methods. 5:2100111
Cells are the basic building blocks of biological systems, with inherent unique molecular features and development trajectories. The study of single cells facilitates in-depth understanding of cellular diversity, disease processes, and organization o
Autor:
Qingyu Ruan, Xing Xu, Zhi Zhu, Yanling Song, Chaoyong Yang, Bingqian Lin, Tian Tian, Wei Wang, Jingjing Guo
Publikováno v:
Analytical chemistry. 91(1)
Autor:
Shuichao Lin, Wei Wang, Qingyu Ruan, Chaoyong James Yang, Leiji Zhou, Fenxiang Zou, Zhi Zhu, Mingxia Zhang, Xiaoye Lin, Yanling Song
Publikováno v:
Biosensorsbioelectronics. 126
To explore genome mutation meaningfully, it is in urgent need to develop an automated and inexpensive platform for DNA mutation analysis. Digital microfluidics is a powerful platform for a broad range of applications due to the advantages of high aut