Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Qingyi Zheng-Fischhöfer"'
Autor:
Jörg Strotmann, Harald Reucher, Qingyi Zheng-Fischhöfer, Elke Winterhager, James I. Nagy, Elisabeth Petrasch-Parwez, Markus Kretz, Klaus Willecke, B.D. Lynn, Marc Schnichels, Stephen J. Lye, Mark Kibschull
Publikováno v:
Developmental Biology. 312(1):258-271
The gap junction gene Connexin31.1 has been reported to be expressed predominantly in the epidermis of murine skin. To study the function of this gene, we generated mice in which the coding DNA of the Connexin31.1 gene was replaced by lacZ reporter c
Autor:
J.O. Schwab, Klaus Tiemann, Gaby Schwarz, Qingyi Zheng-Fischhöfer, Jung-Sun Kim, Mark Kibschull, Klaus Willecke, Alexander Ghanem, Elke Winterhager, James I. Nagy
Publikováno v:
Journal of Cell Science. 119:693-701
In the gastrulating mouse embryo, the gap junction protein connexin43 is expressed exclusively in cells derived from the inner cell mass, whereas connexin31 is expressed in cells of the trophoblast lineage. Since connexin43 and connexin31 do not form
Autor:
Jacek Biernat, Laurent Meijer, Eva-Maria Mandelkow, Eckhard Mandelkow, Yong-Zhong Wu, Qingyi Zheng-Fischhöfer, Thomas Timm
Publikováno v:
Molecular Biology of the Cell. 13:4013-4028
Protein kinases of the microtubule affinity-regulating kinase (MARK) family were originally discovered because of their ability to phosphorylate certain sites in tau protein (KXGS motifs in the repeat domain). This type of phosphorylation is enhanced
Autor:
R. Godemann, Eva-Maria Mandelkow, Jacek Biernat, Karlheinz Baumann, Karsten Stamer, Eckhard Mandelkow, B. Trinczek, Ute Preuss, Qingyi Zheng-Fischhöfer, Susanne Illenberger
Publikováno v:
Molecular Biology of the Cell. 9:1495-1512
In Alzheimer’s disease the neuronal microtubule-associated protein tau becomes highly phosphorylated, loses its binding properties, and aggregates into paired helical filaments. There is increasing evidence that the events leading to this hyperphos
Autor:
Ildiko Toma, Fiona Hanner, Li E. Yang, Klaus Willecke, Janos Peti-Peterdi, Qingyi Zheng-Fischhöfer, Marc Schnichels, Alicia A. McDonough
Publikováno v:
Cell communicationadhesion. 15(1)
Several isoforms of connexin (Cx) proteins have been identified in a variety of tissues where they play a role in intercellular communication, either as the components of gap junctions or as large, nonselective pores known as hemichannels. This inves
Autor:
Ekrem Dere, Qingyi Zheng-Fischhöfer, Joseph P. Huston, U.A. Gironi Carnevale, Marc Schnichels, Klaus Willecke, L.A. Ruocco, Davide Viggiano, Armin Zlomuzica, A.G. Sadile
Publikováno v:
Neuroscience. 153(2)
Neuronal gap junctions in the brain, providing intercellular electrotonic signal transfer, have been implicated in physiological and behavioral correlates of learning and memory. In connexin31.1 (Cx31.1) knockout (KO) mice the coding region of the Cx
Autor:
James I. Nagy, Fiona McCulloch, Markus Kretz, Qingyi Zheng-Fischhöfer, Klaus Willecke, Marc Schnichels, Joachim Degen, Ekrem Dere, Joseph P. Huston, Heinz Breer, Harald Reucher, Jörg Strotmann, Janos Peti-Peterdi, Nadine Loscher
Publikováno v:
European journal of cell biology. 86(11-12)
We have generated connexin30.3-deficient mice in which the coding region of the connexin30.3 gene was replaced by the lacZ reporter gene. The expression pattern of this connexin was characterized using beta-galactosidase staining and immunoblot analy
Autor:
R. Godemann, Eva-Maria Mandelkow, Susanne Illenberger, Eckhard Mandelkow, Qingyi Zheng-Fischhöfer, Jacek Biernat
Publikováno v:
European journal of biochemistry. 252(3)
AT100 is a monoclonal antibody highly specific for phosphorylated Tau in Alzheimer paired helical filaments. Here we show that the epitope is generated by a complex sequence of sequential phosphorylation, first of Ser199, Ser202 and Thr205 (around th
Publikováno v:
Heart Rhythm. 3:S182-S183