Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Qingxia Fang"'
Publikováno v:
Cancer Biology & Therapy, Vol 23, Iss 1, Pp 1-8 (2022)
Defects in tRNA expressions and modifications had been linked to various types of tumorigenesis and progression in recent studies, including colorectal cancer. In the present study, we evaluated transcript levels of mitochondrial tyrosyl-tRNA synthet
Externí odkaz:
https://doaj.org/article/6783e5c655204b4da0e17a13e313e486
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281402 (2023)
BackgroundSunitinib was approved several years ago as a first-line drug for treating metastatic renal cell carcinoma (mRCC); however, its high price and broad side effects when administered at the standard dose have limited its clinical use. A clinic
Externí odkaz:
https://doaj.org/article/776aa9cac81d488e81e0fce4dc9621ee
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Objective Neratinib plus capecitabine (Ner+Cap) were proved to be clinically beneficial as a third-line treatment for women with human epidermal growth factor receptor-2 (HER2) positive metastatic breast cancer (MBC). The objective of this study was
Externí odkaz:
https://doaj.org/article/59b2d26346254d8aa66b691292ca36d0
Autor:
Yue Wu, Ruijie Lu, Yujie Lin, Jinjin Wang, Zijian Lou, Xiaochun Zheng, Ling Zhang, Ruolang Pan, Gang Lu, Qingxia Fang
Publikováno v:
Environmental Science and Pollution Research. 30:47780-47786
Long-term exposure to diethylhexyl phthalate (DEHP), an endocrine-disrupting chemical (EDCs) and plasticizer widely used in consumer products, has been reported to be significantly positively correlated with increased risks of different human disease
Autor:
Qingxia Fang, Jiana Shi, Jieping Yan, Danfeng Xu, Xiuli Yang, Chenhuan Yu, Xiaolan Ye, Yanfei Shao, Xiaozhou Zou, Ting Liu, Xiaochun Zheng
Publikováno v:
Journal of Cellular and Molecular Medicine
The current study was designed to explore the role and underlying mechanism of lncRNA taurine up‐regulated gene 1 (TUG1) in cardiac hypertrophy. Mice were treated by transverse aortic constriction (TAC) surgery to induce cardiac hypertrophy, and ca
Autor:
Jinying Jiang, Wei Wang, Zixue Xuan Xuan, Lin-qing Liu, Qiang Ye, Xiuli Yang, Xiaolu Tan, Qingxia Fang, Yucheng Zhou, Ziqi Ye, Feng Gao, Guo-bing Zhang
Publikováno v:
International Journal of Oncology
Gastric cancer is an important cancer type worldwide, the anti‑angiogenic agent BC001 can target the vascular endothelial growth factor receptor 2 (VEGFR2), and significantly suppresses the growth of gastric cancer BGC823 cells in vitro and in vivo
Autor:
Guo-bing Zhang, Zixue Xuan, Wanyuan Chen, Shi-bing Wang, Yanfei Shao, Wei Wang, Lin-qing Liu, Jiana Shi, Ziqi Ye, Jinying Jiang, Qingxia Fang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 118, Iss, Pp-(2019)
Bevacizumab (BEV) is widely used for the treatment of patients with recurrent glioblastoma (GBM), but recent evidence demonstrated that BEV induced cytoprotective autophagy, which allows tumor cells to survive. Hydroxychloroquine (HCQ) inhibits lysos
Publikováno v:
Journal of cellular biochemistryREFERENCES. 121(3)
Non-small-cell lung cancer (NSCLC) is an extremely debilitating respiratory malignancy. However, the pathogenesis of NSCLC has not been fully clarified. The main objective of our study was to identify potential microRNAs (miRNAs) and their regulatory
Publikováno v:
Biochemical and biophysical research communications. 498(3)
Fulvestrant is the FDA-approved "pure anti-estrogen" agent for malignant breast cancer therapy. But endocrine resistance causes drug failure. A new approach is desired for fulvestrant-resistant breast cancer (FRBC) therapy. This study aims to find an
Autor:
Meidan Ying, Jian Ma, Bo Yang, Qinjie Weng, Ji Cao, Wen Meng, Qiaojun He, Jun Zhang, Shenglin Ma, Rong Dong, Zibo Chen, Qingxia Fang
Publikováno v:
Oncotarget
Hypoxia is a common phenomenon occurring in the majority of human tumors and has been proved to play an important role in tumor progression. However, it remains unclear that whether the action of hypoxia on macrophages is a main driving force of hypo