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Akademický článek

The Δ33-35 Mutant α-Domain Containing β-Domain-Like M3S9 Cluster Exhibits the Function of α-Domain with M4S11 Cluster in Human Growth Inhibitory Factor

Autor: Qingui Bao, Zhichun Ding, Zhong-Xian Huang, Xiangshi Tan

Publikováno v: Bioinorganic Chemistry and Applications, Vol 2010 (2010)

Neuronal growth inhibitory factor (GIF), also known as metallothionein (metallothionein-3), impairs the survival and neurite formation of cultured neurons. It is known that the α-β domain-domain interaction of hGIF is crucial to the neuron growth i

Externí odkaz: https://doaj.org/article/82ef34133eb04a54b162de3131a0e278

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Akademický článek

The Δ33-35 Mutant α-Domain Containing ß-Domain-Like M3S9 Cluster Exhibits the Function of α-Domain with M9S11 Cluster in Human Growth Inhibitory Factor.

Autor: Qingui Bao¹, Zhichun Ding², Zhong-Xian Huang², Xiangshi Tan¹ xstan@fudan.edu.cn

Publikováno v: Bioinorganic Chemistry & Applications. 2010, Vol. 2010, p1-8. 8p.

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The molecular mechanism for human metallothionein-3 to protect against the neuronal cytotoxicity of Aβ1–42 with Cu ions

Autor: Xiangshi Tan, Zhi-Chun Ding, Qingui Bao, Cuiqing Zhu, Ying Luo, Yuxia Xu, Zhong-Xian Huang

Publikováno v: JBIC Journal of Biological Inorganic Chemistry. 18:39-47

Aggregation and cytotoxicity of Aβ with redox-active metals in neuronal cells have been implicated in the progression of Alzheimer disease. Human metallothionein (MT) 3 is highly expressed in the normal human brain and is downregulated in Alzheimer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5b9795b0be90ede34b54caa4491d90
https://doi.org/10.1007/s00775-012-0947-3

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TheΔ33-35 Mutantα-Domain Containingβ-Domain-LikeM3S9Cluster Exhibits the Function ofα-Domain withM4S11Cluster in Human Growth Inhibitory Factor

Autor: Zhi-Chun Ding, Xiangshi Tan, Zhong-Xian Huang, Qingui Bao

Publikováno v: Bioinorganic Chemistry and Applications. 2010:1-8

Neuronal growth inhibitory factor (GIF), also known as metallothionein (metallothionein-3), impairs the survival and neurite formation of cultured neurons. It is known that theα-βdomain-domain interaction of hGIF is crucial to the neuron growth inh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f18c944fbaa2d0cdac174cc52eef649
https://doi.org/10.1155/2010/294169

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The mechanism for heme to prevent Aβ(1-40) aggregation and its cytotoxicity

Autor: Ying Luo, Pingwei Li, Zhong-Xian Huang, Cuiqing Zhu, Wei Li, Xiangshi Tan, Qingui Bao, Xiaobo Sun

Publikováno v: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 16(5)

The β-amyloid peptide (Aβ) aggregation in the brain, known as amyloid plaques, is a hallmark of Alzheimer's disease (AD). The aberrant interaction of Cu(2+) ion with Aβ potentiates AD by inducing Aβ aggregation and generating neurotoxic reactive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2a4873d1825d27a590aedb3da1331b
https://pubmed.ncbi.nlm.nih.gov/21523435

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The Delta33-35 Mutant alpha-Domain Containing beta-Domain-Like M(3)S(9) Cluster Exhibits the Function of alpha-Domain with M(4)S(11) Cluster in Human Growth Inhibitory Factor

Autor: Qingui, Bao, Zhichun, Ding, Zhong-Xian, Huang, Xiangshi, Tan

Publikováno v: Bioinorganic Chemistry and Applications

Neuronal growth inhibitory factor (GIF), also known as metallothionein (metallothionein-3), impairs the survival and neurite formation of cultured neurons. It is known that the alpha-beta domain-domain interaction of hGIF is crucial to the neuron gro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e83411426d649865d5e5c7d3a66c82c1
https://pubmed.ncbi.nlm.nih.gov/20490351

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