Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Qingtian Huang"'
Autor:
Xiangzong Zeng, Yichen Wang, Min Dai, Wei Li, Qingtian Huang, Lingsha Qin, Yuquan Li, Yanwen Yan, Xiangjun Xue, Fang Yi, Wenhao Li, Langyu He, Qifa Liu, Ling Qi
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Myelodysplastic neoplasms (MDS) are myeloid neoplasms characterized by disordered differentiation of hematopoietic stem cells and a predisposition to acute myeloid leukemia (AML). The underline pathogenesis remains unclear. Method
Externí odkaz:
https://doaj.org/article/02fc2de121cc4f82b5b7b31bfc51f68e
Autor:
Qingtian Huang, Jie Yang, Jiaxing Zhang, Leyi Yao, Baoyi Jiang, Siyuan Du, Fengjin Li, Qian Peng, Lingsha Qin, Yanfen Wang, Ling Qi
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110496- (2024)
Summary: Pancreatic cancer is highly lethal with limited effective treatments. This study explores the therapeutic effects of eupalinolide B (EB) from Eupatorium lindleyanum DC on pancreatic cancer cells. Through cellular functional assays, we observ
Externí odkaz:
https://doaj.org/article/1d1cd3c57f2741a3a5c38889ee4695e9
Autor:
Qingtian Huang, Na Zhang, Jiangtuan Wang, Hua Xu, Leyi Yao, Qianqian Yang, Ding Yan, Xi Chen, Qian Xue, Min Xiao, Jiawen Wu, Xueheng Wu, Qin Liu, Daolin Tang, Xin Chen, Xiaofen Li, Jinbao Liu
Publikováno v:
Genes and Diseases, Vol 10, Iss 6, Pp 2222-2225 (2023)
Externí odkaz:
https://doaj.org/article/a97a27ab0afd44d78b79b9f9def067d3
Autor:
Leyi Yao, Qian Zhao, Ding Yan, Ziying Lei, Yali Hao, Jinghong Chen, Qian Xue, Xiaofen Li, Qingtian Huang, Daolin Tang, Q. Ping Dou, Xin Chen, Jinbao Liu
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 7, Pp 1061-1077 (2022)
Objective: Sorafenib is a first-line drug for advanced hepatocellular carcinoma (HCC). Unfortunately, most patients with HCC do not respond to sorafenib, mainly because of the frequent development of drug resistance. Bilirubin is an end metabolite of
Externí odkaz:
https://doaj.org/article/b8ede69e341042529486d7ed6b70a562
Autor:
Ding Yan, Xiaofen Li, Qianqian Yang, Qingtian Huang, Leyi Yao, Peiquan Zhang, Wenshuang Sun, Shuhui Lin, Q. Ping Dou, Jinbao Liu, Xin Chen
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Deubiquitinates (DUBs) have been suggested as novel promising targets for cancer therapies. Accumulating experimental evidence suggests that some metal compounds have the potential to induce cancer cell death via inhibition of DUBs. We previ
Externí odkaz:
https://doaj.org/article/2c8b1a05ab164a05a04b01ecac564e6d
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 159-172 (2019)
Background: Ubiquitin-proteasome system (UPS) is integral to cell survival by maintaining protein homeostasis, and its dysfunction has been linked to cancer and several other human diseases. Through counteracting ubiquitination, deubiquitinases (DUBs
Externí odkaz:
https://doaj.org/article/ea4fe31302844726b0e5e8cf2ee027e8
Autor:
Li Yang, Xin Chen, Qianqian Yang, Jinghong Chen, Qingtian Huang, Leyi Yao, Ding Yan, Jiawen Wu, Peiquan Zhang, Daolin Tang, Nanshan Zhong, Jinbao Liu
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Proteasomal deubiquitinase (DUB) inhibition has been found to be effective in experimental cancer therapy by inducing proteasome inhibition and apoptosis. Ferroptosis is a form of regulated cell death characterized by an iron-dependent lipid peroxida
Externí odkaz:
https://doaj.org/article/580aa6a2490e4bf6a8b852e150bf7576
Autor:
Xin Chen, Qianqian Yang, Jinghong Chen, Peiquan Zhang, Qingtian Huang, Xiaolan Zhang, Li Yang, Dacai Xu, Chong Zhao, Xuejun Wang, Jinbao Liu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 2, Pp 780-797 (2018)
Background/Aims: The ubiquitin proteasome system (UPS) is responsible for the degradation of most intracellular proteins, and proteasomal deubiquitinases (DUBs) have recently been highlighted as novel anticancer targets. It is well documented that co
Externí odkaz:
https://doaj.org/article/fbb04df17ff54b529ec415672a1ba0b4
Autor:
Leyi Yao, Ding Yan, Baoyi Jiang, Qian Xue, Xi Chen, Qingtian Huang, Ling Qi, Daolin Tang, Xin Chen, Jinbao Liu
Publikováno v:
Free Radical Biology and Medicine. 203:1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28441f5b7a4e2707ce41f91d6d85136a
https://doi.org/10.1016/j.freeradbiomed.2023.03.263
https://doi.org/10.1016/j.freeradbiomed.2023.03.263
Autor:
Qianqian Yang, Ding Yan, Chaoying Zou, Qian Xue, Shuhui Lin, Qingtian Huang, Xiaofen Li, Daolin Tang, Xin Chen, Jinbao Liu
Publikováno v:
Experimental & Molecular Medicine. 54:2047-2059
Triple-negative breast cancer (TNBC) is a heterogeneous malignancy in women. It is associated with poor prognosis, aggressive malignant behavior, and limited treatment options. In the ubiquitin‒proteasome system (UPS), deubiquitinases (DUBs) are po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35461b684978bebfd0fb18140ad38207
https://doi.org/10.1038/s12276-022-00890-1
https://doi.org/10.1038/s12276-022-00890-1