Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Qingtian, Guan"'
Autor:
Meng Zhang, Sabir Adroub, Roy Ummels, Mohammed Asaad, Lei Song, Arnab Pain, Wilbert Bitter, Qingtian Guan, Abdallah M. Abdallah
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Mycobacteria is a diverse genus that includes both innocuous environmental species and serious pathogens like Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium ulcerans, the causative agents of tuberculosis, leprosy, and Bu
Externí odkaz:
https://doaj.org/article/d6945d1d86bb48d68b1bbac72356690a
Autor:
Jiaqi Fu, Siying Li, Hongxin Guan, Chuang Li, Yan-Bo Zhao, Tao-Tao Chen, Wei Xian, Zhengrui Zhang, Yao Liu, Qingtian Guan, Jingting Wang, Qiuhua Lu, Lina Kang, Si-Ru Zheng, Jinyu Li, Shoujing Cao, Chittaranjan Das, Xiaoyun Liu, Lei Song, Songying Ouyang, Zhao-Qing Luo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The intracellular bacterial pathogen Legionella pneumophila modulates host cell functions by secreting multiple effectors with diverse biochemical activities. In particular, effectors of the SidE family interfere with host protein ubiquitina
Externí odkaz:
https://doaj.org/article/97d8f676d9ec44799e5facaa65cf2504
Publikováno v:
eLife, Vol 12 (2024)
Identification of unique essential bacterial genes is important for not only the understanding of their cell biology but also the development of new antimicrobials. Here, we report a previously unrecognized core component of the Acinetobacter baumann
Externí odkaz:
https://doaj.org/article/5fe6247504954514a073ae56c0f59141
Autor:
Yu Sun, Lidong Wang, Ming Zhang, Jing Jie, Qingtian Guan, Jiaqi Fu, Xiao Chu, Dong Chen, Chunxiuli Li, Lei Song, Zhao-Qing Luo
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Pathogenic bacteria of the Acinetobacter genus pose a severe threat to human health worldwide due to their strong adaptability, tolerance, and antibiotic resistance. Most isolates of these bacteria harbor a type VI secretion system (T6SS) th
Externí odkaz:
https://doaj.org/article/ee882f73676d4f168996d01f82613e82
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e24109- (2024)
Research has shown a connection between inflammation and chronic obstructive pulmonary disease (COPD), however the relationship between inflammation mediators and COPD causation remains unknown. To investigate the causal relationship of mediators of
Externí odkaz:
https://doaj.org/article/0c72432b626b4448b2aa31a96e817baf
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTPlasmid conjugation plays an important role in the dissemination of antibiotic-resistance genes. The emergence of multidrug-resistant isolates of Acinetobacter baumannii poses grave challenges in treating infections caused by this notorious n
Externí odkaz:
https://doaj.org/article/79ee52459bf146cdbd98d5d2aaf7c8dd
Autor:
Tobias Mourier, Muhammad Shuaib, Sharif Hala, Sara Mfarrej, Fadwa Alofi, Raeece Naeem, Afrah Alsomali, David Jorgensen, Amit Kumar Subudhi, Fathia Ben Rached, Qingtian Guan, Rahul P. Salunke, Amanda Ooi, Luke Esau, Olga Douvropoulou, Raushan Nugmanova, Sadhasivam Perumal, Huoming Zhang, Issaac Rajan, Awad Al-Omari, Samer Salih, Abbas Shamsan, Abbas Al Mutair, Jumana Taha, Abdulaziz Alahmadi, Nashwa Khotani, Abdelrahman Alhamss, Ahmed Mahmoud, Khaled Alquthami, Abdullah Dageeg, Asim Khogeer, Anwar M. Hashem, Paula Moraga, Eric Volz, Naif Almontashiri, Arnab Pain
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
In this study, the authors sequence 892 SARS-CoV-2 genomes from Saudi Arabia and describe population dynamics and importations into the country. They identify a nucleocapsid protein mutation associated with increased viral load and host interactions
Externí odkaz:
https://doaj.org/article/267fc5bbbd974a3484185a42d668a1ee
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Many Gram-negative bacteria deploy a type VI secretion system (T6SS) to inject toxins into target cells to promote their survival and replication in complex environments. Here, we report that Acinetobacter baumannii uses its T6SS to kill fun
Externí odkaz:
https://doaj.org/article/b58dd343246d489b974d28cc21a6b732
Autor:
Tobias Mourier, Denise Anete Madureira de Alvarenga, Abhinav Kaushik, Anielle de Pina-Costa, Olga Douvropoulou, Qingtian Guan, Francisco J. Guzmán-Vega, Sarah Forrester, Filipe Vieira Santos de Abreu, Cesare Bianco Júnior, Julio Cesar de Souza Junior, Silvia Bahadian Moreira, Zelinda Maria Braga Hirano, Alcides Pissinatti, Maria de Fátima Ferreira-da-Cruz, Ricardo Lourenço de Oliveira, Stefan T. Arold, Daniel C. Jeffares, Patrícia Brasil, Cristiana Ferreira Alves de Brito, Richard Culleton, Cláudio Tadeu Daniel-Ribeiro, Arnab Pain
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Plasmodium simium, a malaria parasite of non-human primates (NHP), was recently shown to cause zoonotic infections in humans in Brazil. We sequenced the P. simium genome to investigate its evolutionary history and to identify any
Externí odkaz:
https://doaj.org/article/bd905018ccdf423c80ff63c02d294d29
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Gastric cancer is one of the most important malignancies with poor prognosis. Ferroptosis and cuproptosis are newly discovered metal-dependent types of programmed cell death, which may directly affect the outcome of gastric cancer. Long n
Externí odkaz:
https://doaj.org/article/9af373aaa2084866bba4b7e743fbe2f9