Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Qingshou Chen"'
Autor:
Petri Elo, Xiang-Guo Li, Heidi Liljenbäck, Semi Helin, Jarmo Teuho, Kalle Koskensalo, Virva Saunavaara, Päivi Marjamäki, Vesa Oikonen, Jenni Virta, Qingshou Chen, Philip S. Low, Juhani Knuuti, Sirpa Jalkanen, Laura Airas, Anne Roivainen
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-18 (2019)
Abstract Background Folate receptor-β (FR-β) is a cell surface receptor that is significantly upregulated on activated macrophages during inflammation and provides a potential target for folate-based therapeutic and diagnostic agents. FR-β express
Externí odkaz:
https://doaj.org/article/fd311c450a324abdaa5010215edd495c
Autor:
Johanna M. U. Silvola, Xiang-Guo Li, Jenni Virta, Päivi Marjamäki, Heidi Liljenbäck, Jarkko P. Hytönen, Miikka Tarkia, Virva Saunavaara, Saija Hurme, Senthil Palani, Harri Hakovirta, Seppo Ylä-Herttuala, Pekka Saukko, Qingshou Chen, Philip S. Low, Juhani Knuuti, Antti Saraste, Anne Roivainen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Inflammation plays an important role in the development of atherosclerosis and its complications. Because the folate receptor β (FR-β) is selectively expressed on macrophages, an FR targeted imaging agent could be useful for assessment of
Externí odkaz:
https://doaj.org/article/0ba0ded919c04de1bea8c1128f7cd5be
Autor:
Durga M. S. H. Chandrupatla, Gerrit Jansen, Ricardo Vos, Mariska Verlaan, Qingshou Chen, Philip S. Low, Albert D. Windhorst, Adriaan A. Lammertsma, Conny J. van der Laken, Carla F. M. Molthoff
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-9 (2017)
Abstract Background Folate receptor β (FRβ) is involved in facilitating cellular uptake of folates and anti-folates (such as methotrexate (MTX)). In rheumatoid arthritis, FRβ is expressed on synovial macrophages and recently has been explored as a
Externí odkaz:
https://doaj.org/article/5a885222fd434f019869ad0af1e3e335
Autor:
Hong Yang, Minglong Shao, Liangmiao Chen, Qingshou Chen, Lechu Yu, Lingqiao Cai, Zhenzhen Lin, Chi Zhang, Xuemian Lu
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99611 (2014)
Thyroid dysfunction during pregnancy is associated with multiple adverse outcomes, but whether all women should be screened for thyroid disorders during pregnancy remains controversial.To evaluate the effectiveness of the targeted high risk case-find
Externí odkaz:
https://doaj.org/article/95db7e84cfcc4217a0484981bae40d43
Autor:
Qingshou Chen, S. Pieplenbosch, Adriaan A. Lammertsma, Albert D. Windhorst, Gerrit Jansen, Conny J. van der Laken, N. J. F. Verweij, Alexandre E Voskuyl, Otto S. Hoekstra, Marieke M. ter Wee, Philip S. Low, Stefan T G Bruijnen, Maqsood Yaqub
Publikováno v:
Verweij, N J F, Yaqub, M, Bruijnen, S T G, Pieplenbosch, S, ter Wee, M M, Jansen, G, Chen, Q, Low, P S, Windhorst, A D, Lammertsma, A A, Hoekstra, O S, Voskuyl, A E & van der Laken, C J 2020, ' First in man study of [18F]fluoro-PEG-folate PET: a novel macrophage imaging technique to visualize rheumatoid arthritis ', Scientific Reports, vol. 10, no. 1, 1047 . https://doi.org/10.1038/s41598-020-57841-x
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, 10(1):1047. Nature Publishing Group
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, 10(1):1047. Nature Publishing Group
Non-invasive imaging of arthritis activity in rheumatoid arthritis (RA) patients using macrophage PET holds promise for early diagnosis and therapeutic response monitoring. Previously obtained results with macrophage tracer (R)-[11C]PK11195 were enco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a5bab9d670df6f44a14cb9e8e9013b
https://research.vumc.nl/en/publications/c76703cf-a87a-47c4-bd60-f7cd9dbfeb94
https://research.vumc.nl/en/publications/c76703cf-a87a-47c4-bd60-f7cd9dbfeb94
Autor:
Qingshou Chen, Pekka Taimen, Mikko I. Mäyränpää, Vesa Oikonen, Philip S. Low, Ville Kytö, Juhani Knuuti, Jenni Virta, Päivi Marjamäki, Arghavan Jahandideh, Heidi Liljenbäck, Jukka Lehtonen, Antti Saraste, Xiang-Guo Li, Mia Ståhle, Sauli Uotila, Anne Roivainen
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 61(11)
Rationale: Currently available imaging techniques have limited specificity for the detection of active myocardial inflammation. Aluminum fluoride-18-labeled 1,4,7-triazacyclononane-N,N′,N″-triacetic acid conjugated folate (18F-FOL) is a positron
Autor:
Juhani Knuuti, Vesa Oikonen, Virva Saunavaara, Laura Airas, Anne Roivainen, Philip S. Low, Heidi Liljenbäck, Jarmo Teuho, Jenni Virta, Semi Helin, Kalle Koskensalo, Xiang-Guo Li, Petri Elo, Päivi Marjamäki, Sirpa Jalkanen, Qingshou Chen
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-18 (2019)
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-18 (2019)
Background Folate receptor-β (FR-β) is a cell surface receptor that is significantly upregulated on activated macrophages during inflammation and provides a potential target for folate-based therapeutic and diagnostic agents. FR-β expression in ce
Autor:
Qingshou Chen, Daniel Rubins, Shu-An Lin, Xiangjun Meng, Hyking Haley, Philip S. Low, Dinko Gonzalez Trotter, Paul McQuade, Patricia Miller, Zhizhen Zeng
Publikováno v:
Molecular Pharmaceutics. 14:4353-4361
The folate receptor (FR) has been established as a promising target for imaging and therapy of cancer (FR-α), inflammation, and autoimmune diseases (FR-β). Several folate-based PET radiotracers have been reported in the literature, but an 18F- labe
Autor:
Michael K. Wendt, Remah Ali, Kyle E. Harvey, Vincent Jo Davisson, Anthony M. Pedley, Matthew D. Bartolowits, Wells S. Brown, Qingshou Chen
Publikováno v:
ACS Chemical Biology. 12:2371-2378
The discovery of compounds that selectively modulate signaling and effector proteins downstream of EGFR could have important implications for understanding specific roles for pathway activation. A complicating factor for receptor tyrosine kinases is
Autor:
Philip S. Low, Xiang-Guo Li, Kyto, Anne Roivainen, Pekka Taimen, Antti Saraste, Mia Ståhle, Qingshou Chen, Päivi Marjamäki, Jere Virta, U Uotila, Juhani Knuuti, A Jahandideh
Publikováno v:
European Heart Journal - Cardiovascular Imaging. 20