Deep learning-enabled pelvic ultrasound images for accurate diagnosis of ovarian cancer in China: a retrospective, multicentre, diagnostic study

Autor: Yue Gao, MD, Shaoqing Zeng, MD, Xiaoyan Xu, ProfMD, Huayi Li, Shuzhong Yao, ProfPhD, Kun Song, ProfPhD, Xiao Li, BS, Lingxi Chen, PhD, Junying Tang, ProfPhD, Hui Xing, ProfPhD, Zhiying Yu, ProfPhD, Qinghua Zhang, ProfPhD, Shue Zeng, ProfPhD, Cunjian Yi, ProfPhD, Hongning Xie, ProfPhD, Xiaoming Xiong, BS, Guangyao Cai, MD, Zhi Wang, MS, Yuan Wu, MS, Jianhua Chi, BS, Xiaofei Jiao, BS, Yan Qin, MS, Xiaogang Mao, MD, Yu Chen, MD, Xin Jin, MD, Qingqing Mo, MD, Pingbo Chen, ProfMD, Yi Huang, ProfMD, Yushuang Shi, MD, Junmei Wang, ProfPhD, Yimin Zhou, MD, Shuping Ding, MD, Shan Zhu, MD, Xin Liu, ProfMD, Xiangyi Dong, MD, Lin Cheng, MD, Linlin Zhu, MD, Huanhuan Cheng, MD, Li Cha, MD, Yanli Hao, MS, Chunchun Jin, MD, Ludan Zhang, MD, Peng Zhou, BS, Meng Sun, MS, Qin Xu, MS, Kehua Chen, BS, Zeyan Gao, MS, Xu Zhang, BS, Yuanyuan Ma, MS, Yan Liu, MD, Liling Xiao, MS, Li Xu, MD, Lin Peng, BS, Zheyu Hao, MD, Mi Yang, MD, Yane Wang, MD, Hongping Ou, MD, Yongmei Jia, MD, Lihua Tian, MD, Wei Zhang, MD, Ping Jin, MS, Xun Tian, ProfMD, Lei Huang, MD, Zhen Wang, MD, Jiahao Liu, BS, Tian Fang, MS, Danmei Yan, BS, Heng Cao, BS, Jingjing Ma, MD, Xiaoting Li, MD, Xu Zheng, BS, Hua Lou, BS, Chunyan Song, BS, Ruyuan Li, BS, Siyuan Wang, BS, Wenqian Li, MD, Xulei Zheng, MD, Jing Chen, MD, Guannan Li, BS, Ruqi Chen, MS, Cheng Xu, MS, Ruidi Yu, MS, Ji Wang, MS, Sen Xu, MD, Beihua Kong, ProfPhD, Xing Xie, ProfPhD, Ding Ma, ProfPhD, Qinglei Gao, ProfPhD

Publikováno v: The Lancet: Digital Health, Vol 4, Iss 3, Pp e179-e187 (2022)

Summary: Background: Ultrasound is a critical non-invasive test for preoperative diagnosis of ovarian cancer. Deep learning is making advances in image-recognition tasks; therefore, we aimed to develop a deep convolutional neural network (DCNN) model

Externí odkaz: https://doaj.org/article/557389c903e04fe284a592be5931df32

Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradationResearch in context

Autor: Yingyan Han, Peng Wu, Zhi Wang, Zeyu Zhang, Shujuan Sun, Jia Liu, Song Gong, Peipei Gao, Tomoo Iwakuma, Miguel Angel Molina-Vila, Benjamin Ping-Chi Chen, Yu Zhang, Teng Ji, Qingqing Mo, Pingbo Chen, Junbo Hu, Shixuan Wang, Jianfeng Zhou, Hua Lu, Qinglei Gao

Publikováno v: EBioMedicine, Vol 40, Iss , Pp 92-105 (2019)

Background: Ubiquinol-cytochrome C reductase core protein II (QCR2) is essential for mitochondrial functions, yet, its role in cancer development has remained elusive. Methods: The expression of QCR2 in cancer patients was assessed by immunohistochem

Externí odkaz: https://doaj.org/article/538606e3a04a433d81a758005934988d

Correction: Ubiquitin B in Cervical Cancer: Critical for the Maintenance of Cancer Stem-Like Cell Characters.

Autor: Yuan Tian, Wencheng Ding, Yingying Wang, Teng Ji, Shujuan Sun, Qingqing Mo, Pingbo Chen, Yong Fang, Jia Liu, Beibei Wang, Jianfeng Zhou, Ding Ma, Peng Wu

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0152813 (2016)

Externí odkaz: https://doaj.org/article/d4c99146710c421eaec3fb0f49e52212

Prognostic implications of tumour-infiltrating lymphocytes for recurrence in epithelial ovarian cancer

Autor: Xin Jin, Yue Gao, Pingbo Chen, Qingqing Mo, Yuan Wu, Lingxi Chen

Publikováno v: Clin Exp Immunol

The recurrence of patients with epithelial ovarian cancer (EOC) is largely attributed to tumour cells escaping from the surveillance of immune cells. However, to date there is a lack of studies that have systematically evaluated the associations betw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296052bdf86c80781037a1fafa9d95d0
https://doi.org/10.1111/cei.13639

The LIV-1-GRPEL1 axis adjusts cell fate during anti-mitotic agent-damaged mitosis

Autor: Shixuan Wang, Junbo Hu, Yue Gao, Qinglei Gao, Yang Zhang, Jianfeng Zhou, Yang Cao, Ding Ma, Ling Xi, Yuan Wu, Gang Chen, Beibei Wang, Yuan Tian, Peng Wu, Pingbo Chen, Xin Jin, Yong Fang, Qingqing Mo

Publikováno v: EBioMedicine, Vol 49, Iss, Pp 26-39 (2019)
EBioMedicine

Background: Understanding how cells respond to mitotic poisons is of great biomedical and clinical significance. However, it remains unknown how cell-death or survival is determined during exposure to anti-mitotic drugs. Methods: The biological effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6494c2d6971d4530fef7c233e12b9f
https://doi.org/10.1016/j.ebiom.2019.09.054