Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Qingqin Gao"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-25 (2024)
Abstract Cell and gene therapies hold tremendous promise for treating a range of difficult-to-treat diseases. However, concerns over the safety and efficacy require to be further addressed in order to realize their full potential. Synthetic receptors
Externí odkaz:
https://doaj.org/article/21d9a2bf14cd4d2284cef79b1f5e8462
Autor:
Tongtong Cui, Bingyu Cai, Yao Tian, Xin Liu, Chen Liang, Qingqin Gao, Bojin Li, Yali Ding, Rongqi Li, Qi Zhou, Wei Li, Fei Teng
Publikováno v:
Advanced Science, Vol 11, Iss 19, Pp n/a-n/a (2024)
Abstract CRISPR‐based gene therapies are making remarkable strides toward the clinic. But the large size of most widely used Cas endonucleases including Cas9 and Cas12a restricts their efficient delivery by the adeno‐associated virus (AAV) for in
Externí odkaz:
https://doaj.org/article/ffcfb042a0294c1aa00b6576a769f195
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-7 (2019)
Abstract CRISPR-based nucleic acid detection methods are reported to facilitate rapid and sensitive DNA detection. However, precise DNA detection at the single-base resolution and its wide applications including high-fidelity SNP genotyping remain to
Externí odkaz:
https://doaj.org/article/19280f8e0762415ab66d2f225d7c8b98
Autor:
Fei Teng, Jing Li, Tongtong Cui, Kai Xu, Lu Guo, Qingqin Gao, Guihai Feng, Chuanyuan Chen, Dali Han, Qi Zhou, Wei Li
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract CRISPR-Cas12a/Cpf1, a single RNA-guided endonuclease system, provides a promising tool for genome engineering. However, only three Cas12a orthologs have been employed for mammalian genome editing, and the editing efficiency as well as target
Externí odkaz:
https://doaj.org/article/ef19e2ad7d1c4c9788a858a91d36f8cb
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 5, p 1175 (2022)
Objective: The objective of this study was to analyze the clinical features and risk factors of Urrets-Zavalia syndrome (UZS) after penetrating keratoplasty (PKP). Methods: The medical records of 152 patients who underwent PKP at the Department of Op
Externí odkaz:
https://doaj.org/article/38bf6ffdc82a45f998c13aff5b9b0500
Autor:
Xuehan Sun, Bin Qu, Xinge Wang, Haiping Jiang, Qi Zhou, Yihuan Mao, Ruiqi Rachel Wang, Chen Liang, Sen Fang, Qi Gu, Wei Li, Lu Guo, Yangcan Chen, Qingqin Gao, Moyu Dai, Guihai Feng
Publikováno v:
Cell Discovery
Cell Discovery, Vol 6, Iss 1, Pp 1-4 (2020)
Cell Discovery, Vol 6, Iss 1, Pp 1-4 (2020)
Autor:
Liu Wang, Haiping Jiang, Xinge Wang, Qi Zhou, Yihuan Mao, Sen Fang, Yangcan Chen, Lu Guo, Qingqin Gao, Guihai Feng, Wei Li, Xuehan Sun, Bin Qu, Qi Gu, Moyu Dai, Ruiqi Rachel Wang, Chen Liang
The novel coronavirus (CoV) disease termed COVID-19 (Coronavirus Disease-19) caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) is causing a massive pandemic worldwide, threatening public health systems across the globe. During th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3c0dbaf0f2939b90301c78e554d0eb
https://doi.org/10.1101/2020.04.10.023358
https://doi.org/10.1101/2020.04.10.023358
Publikováno v:
Genome Biology
Genome Biology, Vol 20, Iss 1, Pp 1-7 (2019)
Genome Biology, Vol 20, Iss 1, Pp 1-7 (2019)
CRISPR-based nucleic acid detection methods are reported to facilitate rapid and sensitive DNA detection. However, precise DNA detection at the single-base resolution and its wide applications including high-fidelity SNP genotyping remain to be explo
Autor:
Dali Han, Kai Xu, Chuanyuan Chen, Qi Zhou, Tongtong Cui, Fei Teng, Wei Li, Jing Li, Qingqin Gao, Lu Guo, Guihai Feng
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-6 (2019)
Genome Biology
Genome Biology
CRISPR-Cas12a/Cpf1, a single RNA-guided endonuclease system, provides a promising tool for genome engineering. However, only three Cas12a orthologs have been employed for mammalian genome editing, and the editing efficiency as well as targeting cover
Figure S1. Non-specific DNase activity is conserved across Cas12 proteins. Figure S2. The RuvC domain is responsible for ssDNA trans-cleavage. Figure S3. Preference for Cas12b-mediated trans-activated cleavage of non-specific ssDNA. Figure S4. Sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0606be6a994a00029aff86e4955ba32d