Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Qingning Shu"'
Autor:
Xinlei Yu, Dejiang Ni, Yuchuang Li, Jingtao Zhou, Qingning Shu, Andong Qiu, Chang He, Yuqiong Chen
Publikováno v:
LWT. 130:109535
This study focused on non-targeted metabolomics analysis of the relationship of the chemical composition, quality traits, bioactivity of black tea (Camellia sinensis L.) with five withering degrees (WD65, WD60, WD55, WD50, and WD45, corresponding to
Autor:
Qingning Shu, Vasu Nair
Publikováno v:
Medicinal Research Reviews. 28:219-232
Inosine monophosphate dehydrogenase (IMPDH) is a key enzyme of de novo purine nucleotide biosynthesis and is viewed as an important target in the quest for discovery of drugs in the antiviral, antibacterial and anticancer therapeutic areas. This revi
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 26:651-654
Our interest in the discovery of molecules with antiviral activity against RNA viruses led us to the design of ribonucleosides with surrogate bases with the intent of using inhibition of inosine monophosphate dehydrogenase (IMPDH) as a probe for anti
Publikováno v:
Journal of the American Chemical Society. 127:15983-15988
There is a discrepancy between the observed and calculated stability of trans-cycloheptene (t-CHP). Generation of t-CHP has always led to its low-temperature (-40 degrees C) isomerization to cis-cycloheptene (c-CHP). However, force field and semiempi
Autor:
Guochen Chi, Malik Nishonov, Xiaohui Ma, Sanjay Mishra, Vasu Nair, Vinod Uchil, Maurice Okello, Qingning Shu, Byung I. Seo
Publikováno v:
ACS medicinal chemistry letters. 2(12)
Worldwide research efforts in drug discovery involving HIV integrase have produced only one compound, raltegravir, that has been approved for clinical use in HIV/AIDS. As resistance, toxicity and drug-drug interactions are recurring issues with all c
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(5)
The etiological agents of dengue fever (DF) and dengue hemorrhagic fever (DHF) are four closely related dengue viruses, which are antigenically similar but immunologically distinct serotypes of the family called Flavivirus.1–3 The major vector for
Autor:
Qingning Shu, Vasu Nair
Publikováno v:
ChemInform. 39
Inosine monophosphate dehydrogenase (IMPDH) is a key enzyme of de novo purine nucleotide biosynthesis and is viewed as an important target in the quest for discovery of drugs in the antiviral, antibacterial and anticancer therapeutic areas. This revi
Publikováno v:
ChemInform. 39
Our interest in the discovery of molecules with antiviral activity against RNA viruses led us to the design of ribonucleosides with surrogate bases with the intent of using inhibition of inosine monophosphate dehydrogenase (IMPDH) as a probe for anti
Autor:
Vasu Nair, Qingning Shu
Publikováno v:
Antiviral chemistrychemotherapy. 18(5)
Inosine monophosphate (IMP) dehydrogenase (IMPDH) is a significant enzyme in the purine nucleotide biosynthetic pathway. IMPDH is viewed as an important biological target in the quest for drugs in the antiviral therapeutic area. This review article i
Autor:
Malik Nishonov, Fan Zhang, Vasu Nair, Earl R. Kern, Robert W. Sidwell, Xiaohui Ma, Qingning Shu
Publikováno v:
Antiviral Research. 74:A74-A74