Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Qinglian Wen"'
Autor:
Zhihua Ye, Mintao Xiao, Yinping Zhang, Anfu Zheng, Duoli Zhang, Jie Chen, Fukuan Du, Yueshui Zhao, Xu Wu, Mingxing Li, Yu Chen, Shuai Deng, Jing Shen, Xinyi Zhang, Qinglian Wen, Junkai Zhang, Zhangang Xiao
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The presence of cancer stem cells (CSCs) contributes significantly to treatment resistance in various cancers, including head and neck squamous cell carcinoma (HNSCC). Despite this, the relationship between cancer stemness and immunity remai
Externí odkaz:
https://doaj.org/article/c9c449be768546a49a6ee61ff51b551a
Autor:
Yao Zhang, Xu Wu, Dan Li, Rong Huang, Xiangyu Deng, Mingxing Li, Fukuan Du, Yueshui Zhao, Jing Shen, Yu Chen, Pingxiu Zhang, Congcui Hu, Zhangang Xiao, Qinglian Wen
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Cervicovaginal microbiome plays an important role in the persistence of HPV infection and subsequent disease development. However, cervicovaginal microbiota varied cross populations with different habits and regions. Identificatio
Externí odkaz:
https://doaj.org/article/f6412b4010964527a849626ee1e74abc
Autor:
Wenqiao Zhang, Yali Song, Letai Yi, Jinhuan Ou, Junhui Chen, Wei Zhang, Qinglian Wen, Chuanbin Yang, Jigang Wang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 279, Iss , Pp 116462- (2024)
Tris (2-ethylhexyl) phosphate (TEHP) is a frequently used organophosphorus flame retardant with significant ecotoxicity and widespread human exposure. Recent research indicates that TEHP has reproductive toxicity. However, the precise cell mechanism
Externí odkaz:
https://doaj.org/article/f7bd1c28940a4760a18912605d405c07
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundDespite the significant progress made in radiotherapy and chemotherapy for the treatment of cervical cancer, patients with lymph node metastasis still have a poor prognosis. It is widely accepted that lymph node metastasis plays a crucial r
Externí odkaz:
https://doaj.org/article/1db7a42248ff453b984925cc8d379180
Autor:
Yi Qin, Ping Guan, Dan Li, Huailin He, Wenfeng He, Longjing Tan, Xiangyu Deng, Bizhen Liao, Qinglian Wen, Zhenhua Zhang
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundTreatment of metastatic cervical cancer is a tricky issue. Currently, the National Comprehensive Cancer Network (NCCN) guideline recommends chemotherapy combined with bevacizumab for recurrent or metastatic cervical cancer. Still, the recur
Externí odkaz:
https://doaj.org/article/03be686a083445ce9491a6c574056edb
Autor:
Yi Qin, Shangke Huang, Junli Tang, Yu Fan, Xiangyu Deng, Ping Guan, Zhenhua Zhang, Qinglian Wen, Dan Li
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundTreatment for platinum-resistant ovarian cancer is challenging. Currently, platinum-resistant ovarian cancer is typically treated with non-platinum single-agent chemotherapy ± bevacizumab, but the prognosis is often extremely poor. In the
Externí odkaz:
https://doaj.org/article/b27c62a44a694861bbb5d5145327b557
Anoikis resistance––protagonists of breast cancer cells survive and metastasize after ECM detachment
Autor:
Yalan Dai, Xinyi Zhang, Yingjun Ou, Linglin Zou, Duoli Zhang, Qingfan Yang, Yi Qin, Xiuju Du, Wei Li, Zhanpeng Yuan, Zhangang Xiao, Qinglian Wen
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-24 (2023)
Abstract Breast cancer exhibits the highest global incidence among all tumor types. Regardless of the type of breast cancer, metastasis is a crucial cause of poor prognosis. Anoikis, a form of apoptosis initiated by cell detachment from the native en
Externí odkaz:
https://doaj.org/article/f7ce451c6cbd467cb5f447e5f1b89016
Autor:
Mintao Xiao, Chunrong Pang, Shixin Xiang, Yueshui Zhao, Xu Wu, Mingxing Li, Fukuan Du, Yu Chen, Fang Wang, Qinglian Wen, Zhangang Xiao, Zhongming Yang, Jing Shen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract B7 family members act as co-stimulatory or co-inhibitory molecules in the adaptive immune system. Thisstudy aimed to investigate the dysregulation, prognostic value and regulatory network of B7 family members in non-small cell lung cancer (N
Externí odkaz:
https://doaj.org/article/5369f6432307494ab34ed0383481054a
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Objective To analyze the incidence and risk of hypertension associated with poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitors in cancer patients and provide reference for clinicians. Methods We used R software to conduct a meta
Externí odkaz:
https://doaj.org/article/86914e169bc7493c86bafa1637eb4f40
Autor:
Yu Chen, Qingfan Yang, Jinrun Xu, Liyao Tang, Yan Zhang, Fukuan Du, Yueshui Zhao, Xu Wu, Mingxing Li, Jing Shen, Ruilin Ding, Hongying Cao, Wanping Li, Xiaobing Li, Meijuan Chen, Zhigui Wu, Chi Hin Cho, Yu Du, Qinglian Wen, Zhangang Xiao
Publikováno v:
Molecular Therapy: Oncolytics, Vol 27, Iss , Pp 204-223 (2022)
Proteolysis targeting chimera (PROTAC) presents a powerful strategy for targeted protein degradation (TPD). The heterobifunctional PROTAC molecule consists of an E3 ligase ligand covalently linked to a protein of interest (POI) via a linker. PROTAC c
Externí odkaz:
https://doaj.org/article/bf708ce6e296413ebb56d0b8ba2f42f4