Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Qinglei, Gao"'
Publikováno v:
Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)
ABSTRACT Introduction Macrophages are essential in maintaining homeostasis, combating infections, and influencing the process of various diseases, including cancer. Macrophages originate from diverse lineages: Notably, tissue‐resident macrophages (
Externí odkaz:
https://doaj.org/article/ceeb3179e15b473193660cb9f6a6b460
Autor:
Huayi Li, Zikun Peng, Jianqing Zhu, Weidong Zhao, Yi Huang, Ruifang An, Hong Zheng, Pengpeng Qu, Li Wang, Qi Zhou, Danbo Wang, Ge Lou, Jing Wang, Ke Wang, Beihua Kong, Xing Xie, Rutie Yin, John Low, Abdul Malik Rozita, Lim Chun Sen, Yong Chee Meng, Kho Swee Kiong, Jihong Liu, Zhiqing Liang, Weiguo Lv, Yaping Zhu, Weiguo Hu, Wei Sun, Jingya Su, Qiqi Wang, Rongyu Zang, Ding Ma, Qinglei Gao
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background The prospective phase III multi-centre L-MOCA trial (NCT03534453) has demonstrated the encouraging efficacy and manageable safety profile of olaparib maintenance therapy in the Asian (mainly Chinese) patients with platinum-sensiti
Externí odkaz:
https://doaj.org/article/f5e3af1247dd40f9aa8344da62322e0a
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-28 (2024)
Abstract T cells are fundamental components in tumour immunity and cancer immunotherapies, which have made immense strides and revolutionized cancer treatment paradigm. However, recent studies delineate the predicament of T cell dysregulation in tumo
Externí odkaz:
https://doaj.org/article/7d846df1b4ac4f3991ca2e27bf54b911
Autor:
Siyuan Wang, Jiaxin Wang, Yu Xia, Le Zhang, Yueqiang Jiang, Man Liu, Qinglei Gao, Cuntai Zhang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Immune checkpoint blockades have been prized in circumventing and ablating the impediments posed by immunosuppressive receptors, reaching an exciting juncture to be an innovator in anticancer therapy beyond traditional therapeutics. Thus far
Externí odkaz:
https://doaj.org/article/77f363f5e14d4aeab513802a2e6c149d
Autor:
Mengshi Luo, Wenjian Gong, Yuewen Zhang, Huayi Li, Ding Ma, Kongming Wu, Qinglei Gao, Yong Fang
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract T cell-based adoptive cell therapy (ACT) has exhibited excellent antitumoral efficacy exemplified by the clinical breakthrough of chimeric antigen receptor therapy (CAR-T) in hematologic malignancies. It relies on the pool of functional T ce
Externí odkaz:
https://doaj.org/article/e06ce864c10748189c45e05e52da659d
Autor:
Shourong Wang, Yao Liu, Huimin Xiao, Zhongshao Chen, Xiaohang Yang, Jingjing Yin, Yingwei Li, Cunzhong Yuan, Shi Yan, Gang Chen, Qinglei Gao, Beihua Kong, Chaoyang Sun, Kun Song
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-14 (2023)
Abstract Ovarian cancer is resistant to immune checkpoint blockade (ICB) treatment. Combination of targeted therapy and immunotherapy is a promising strategy for ovarian cancer treatment benefit from an improved immune microenvironment. In this study
Externí odkaz:
https://doaj.org/article/78f123d587054a5e9473947f91b46dbd
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background Paclitaxel dose-dense regimen has been controversial in clinical trials in recent years. This systematic review and meta-analysis tried to evaluate the efficacy and safety of paclitaxel dose-dense chemotherapy in primary epithelia
Externí odkaz:
https://doaj.org/article/a7a5931745404e509cc4cf3805a6bfed
Autor:
Guanchen Ma, Shaoqing Zeng, Yingjun Zhao, Jianhua Chi, Li Wang, Qingshui Li, Jing Wang, Shuzhong Yao, Qi Zhou, Youguo Chen, Xiaofei Jiao, Xingyu Liu, Yang Yu, Yabing Huo, Ming Li, Zikun Peng, Ding Ma, Ting Hu, Qinglei Gao
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-10 (2023)
Abstract Background Mucinous epithelial ovarian cancer (mEOC) is a relatively uncommon subtype of ovarian cancer with special prognostic features, but there is insufficient research in this area. This study aimed to develop a nomogram for the cancer-
Externí odkaz:
https://doaj.org/article/ecd790758df1427f9bf93003c88e4d87
Autor:
Xingyu Liu, Yingjun Zhao, Xiaofei Jiao, Yang Yu, Ruyuan Li, Shaoqing Zeng, Jianhua Chi, Guanchen Ma, Yabing Huo, Ming Li, Zikun Peng, Jiahao Liu, Qi Zhou, Dongling Zou, Li Wang, Qingshui Li, Jing Wang, Shuzhong Yao, Youguo Chen, Ding Ma, Ting Hu, Qinglei Gao
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-11 (2023)
Abstract Background To investigate the prognostic relevance of the time to interval debulking surgery (TTS) and the time to postoperative adjuvant chemotherapy (TTC) after the completion of neoadjuvant chemotherapy (NACT). Methods A retrospective rea
Externí odkaz:
https://doaj.org/article/4e7937dc5f0642788234b236058d272a
Autor:
Chao Zhang, Qiang Guo, Lifeng Chen, Zheming Wu, Xiao-Jian Yan, Chengyang Zou, Qiuxue Zhang, Jiahong Tan, Tian Fang, Qunxian Rao, Yang Li, Shizhen Shen, Min Deng, Liewei Wang, Huanyao Gao, Jia Yu, Hu Li, Cheng Zhang, Somaira Nowsheen, Jake Kloeber, Fei Zhao, Ping Yin, Chunbo Teng, Zhongqiu Lin, Kun Song, Shuzhong Yao, Liangqing Yao, Lingying Wu, Yong Zhang, Xiaodong Cheng, Qinglei Gao, Jian Yuan, Zhenkun Lou, Jin-San Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Poly (ADP-ribose) polymerase (PARP) inhibitors are one of the most exciting classes of targeted therapy agents for cancers with homologous recombination (HR) deficiency. However, many patients without apparent HR defects also respond well to
Externí odkaz:
https://doaj.org/article/cca68174bd0f4c47bca6a90059d0f268