Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Qingle Liang"'
Autor:
Luodan A, Linghui Qu, Juncai He, Lingling Ge, Hui Gao, Xiaona Huang, Tianjing You, Hong Gong, Qingle Liang, Siyu Chen, Jing Xie, Haiwei Xu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-25 (2024)
Abstract Background Retinitis pigmentosa is a neurodegenerative disease with major pathologies of photoreceptor apoptosis and immune imbalance. Mesenchymal stem cells (MSCs) have been approved for clinical application for treating various immune-rela
Externí odkaz:
https://doaj.org/article/971bfd24bb0d421ab85282eac9a260e4
Autor:
Nana Bie, Tuying Yong, Zhaohan Wei, Qingle Liang, Xiaoqiong Zhang, Shiyu Li, Xin Li, Jianye Li, Lu Gan, Xiangliang Yang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Immune checkpoint blockade (ICB) therapy, particularly antibodies targeting the programmed death receptor 1 (PD-1) and its ligand (PD-L1), has revolutionized cancer treatment. However, its efficacy as a standalone therapy remains limited. Al
Externí odkaz:
https://doaj.org/article/53e011716d3b432b97c1b9d3bb41abb3
Autor:
Hui Gao, Yuxiao Zeng, Xiaona Huang, Luodan A, Qingle Liang, Jing Xie, Xi Lin, Jing Gong, Xiaotang Fan, Ting Zou, Haiwei Xu
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Retinal degeneration (RD), a group of diseases leading to irreversible vision loss, is characterised by retinal pigment epithelium (RPE) or retinal neuron damage and loss. With fewer risks of immune rejection and tumorigenesis, stem cell‐s
Externí odkaz:
https://doaj.org/article/845d6ef3a1f74f67963b6d055f699021
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
ObjectivesSerum neurofilament light chain (NfL) is a biomarker for neuroaxonal damage, and S100B is a blood marker for cerebral damage. In the present study, we investigated the relationship between serum NfL and S100B levels, severity, and outcomes
Externí odkaz:
https://doaj.org/article/3946f7a145f84efaaec8834fece1cbd2
Autor:
Zhaohan Wei, Xiaoqiong Zhang, Tuying Yong, Nana Bie, Guiting Zhan, Xin Li, Qingle Liang, Jianye Li, Jingjing Yu, Gang Huang, Yuchen Yan, Zelong Zhang, Bixiang Zhang, Lu Gan, Bo Huang, Xiangliang Yang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Durable response rate to anti-PD-1/PD-L1 therapy remains relatively low in patients with cancer. Here the authors show that metformin-loaded mannose-modified macrophage-derived microparticles reprogram the tumor immune microenvironment and improve re
Externí odkaz:
https://doaj.org/article/c971cb339bd0453ca49a321d5bcad548
Autor:
Xiao Wang, Qian Liu, Xiaopei Qiu, Yingran Wang, Hanqing Xu, Qingle Liang, Jun Wang, Mingxuan Gao, Jing Bao, Ming Chen
Publikováno v:
ChemElectroChem. 9
Autor:
Xiangliang Yang, Nana Bie, Haiyan Zhao, Ke Tang, Qingle Liang, Tuying Yong, Haibo Jia, Xiaolong Shi, Bo Huang, Wei Huang, Xiaoqiong Zhang, Zhaohan Wei, Lu Gan
Publikováno v:
Nature Biomedical Engineering. 3:729-740
Extracellular microparticles (MPs) can function as drug-delivery vehicles for anticancer drugs. Here, we show that the softness of MPs derived from tumour-repopulating cells (TRCs) isolated from three-dimensional fibrin gels enhances the MPs' drug-de
Autor:
Bo Huang, Zhaohan Wei, Zelong Zhang, Xin Li, Nana Bie, Qingle Liang, Guiting Zhan, Xiangliang Yang, Tuying Yong, Bixiang Zhang, Jingjing Yu, Xiaoqiong Zhang, Lu Gan, Gang Huang, Jianye Li, Yuchen Yan
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The main challenges for programmed cell death 1(PD-1)/PD-1 ligand (PD-L1) checkpoint blockade lie in a lack of sufficient T cell infiltration, tumor immunosuppressive microenvironment, and the inadequate tumor accumulation and penetration of anti-PD-
Autor:
Tuying Yong, Bo Huang, Xiaolong Shi, Haibo Jia, Qingle Liang, Ke Tang, Nana Bie, Wei Huang, Haiyan Zhao, Xiangliang Yang, Zhaohan Wei, Lu Gan, Xiaoqiong Zhang
Publikováno v:
Nature Biomedical Engineering. 5:481-481
Autor:
Qingle, Liang, Nana, Bie, Tuying, Yong, Ke, Tang, Xiaolong, Shi, Zhaohan, Wei, Haibo, Jia, Xiaoqiong, Zhang, Haiyan, Zhao, Wei, Huang, Lu, Gan, Bo, Huang, Xiangliang, Yang
Publikováno v:
Nature biomedical engineering. 3(9)
Extracellular microparticles (MPs) can function as drug-delivery vehicles for anticancer drugs. Here, we show that the softness of MPs derived from tumour-repopulating cells (TRCs) isolated from three-dimensional fibrin gels enhances the MPs' drug-de