Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Qinghao Zhou"'
Autor:
Lixian Ding, Mingjun Sun, Yanyan Sun, Jinxing Li, Zhicheng Zhang, Shuwei Dang, Jinning Zhang, Bang Yang, Youlin Dai, Qinghao Zhou, Dazhi Zhou, Encheng Li, Shuqi Peng, Guodong Li
Publikováno v:
Cancer Medicine, Vol 13, Iss 13, Pp n/a-n/a (2024)
Abstract Background Gastric cancer (GC) is the fourth leading cause of cancer‐related death worldwide. Minichromsome maintenance proteins family member 8 (MCM8) assists DNA repair and DNA replication. MCM8 exerts tumor promotor function in multiple
Externí odkaz:
https://doaj.org/article/b4d70d46597e42e69da9cff18455d5fc
Publikováno v:
Biomaterials Science (2047-4830); 9/21/2024, Vol. 12 Issue 18, p4607-4629, 23p
Publikováno v:
ACS Nano. 17:9374-9387
Autor:
Jean Felix Mukerabigwi, Rui Tang, Yufei Cao, Fathelrahman Mohammed, Qinghao Zhou, Min Zhou, Zhishen Ge
Publikováno v:
Bioconjugate Chemistry. 34:377-391
Publikováno v:
ACS Macro Letters. 11:543-548
Nanofibers self-assembled from peptides have attracted much attention to inhibit cancer cells. However, there are still some disadvantages, including high concentration for self-assembly and incapability to load drugs, which limit their applications.
Autor:
Junjie Li, Yuheng Wang, Fathelrahman Mohammed, Jingbo Wang, Qinghao Zhou, Nannan Lu, Zhishen Ge
Publikováno v:
Journal of Controlled Release. 339:130-142
The inherent hypoxic microenvironment of solid tumors has an important influence on tumor growth, distant metastasis, and invasiveness. The heterogeneous distribution of hypoxic regions inside tumors limits the therapeutic efficacy of O2-assisted the
Publikováno v:
ACS applied materialsinterfaces. 14(45)
The unique tumor microenvironment (TME) characteristic of severe hypoxia, overexpressed intracellular glutathione (GSH), and elevated hydrogen peroxide (H
Autor:
Xiang Li, Qinghao Zhou, Abd Al-Wali Mohammed M. Japir, Debabrata Dutta, Nannan Lu, Zhishen Ge
Publikováno v:
ACS nano. 16(9)
Immunotherapeutic efficacy of tumors based on immune checkpoint blockade (ICB) therapy is frequently limited by an immunosuppressive tumor microenvironment and cross-reactivity with normal tissues. Herein, we develop reactive oxygen species (ROS)-res
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 18(37)
Photodynamic therapy (PDT) of cancers is seriously restricted by tumor hypoxia. In addition to the intrinsic hypoxic microenvironment, continuous photoirradiation further aggravates intratumoral hypoxia, thereby reducing the PDT effect significantly.
Autor:
Jingbo Wang, Qinghao Zhou, Jean Felix Mukerabigwi, Yuheng Wang, Wendong Ke, Zhishen Ge, Shuang Zhang, Nannan Lu
Publikováno v:
Journal of Controlled Release. 333:500-510
Chemodynamic therapy (CDT) has been proposed to convert tumoral H2O2 into toxic hydroxyl radicals ( OH) via Fenton or Fenton-like reactions for antitumor efficacy, which is frequently limited by low H2O2 concentrations or lack of enough metal ions in