Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Qinghang Meng"'
Publikováno v:
Cells, Vol 13, Iss 9, p 764 (2024)
Excessive extracellular matrix (ECM) deposition is a defining feature of cardiac fibrosis. Most notably, it is characterized by a significant change in the concentration and volume fraction of collagen I, a disproportionate deposition of collagen sub
Externí odkaz:
https://doaj.org/article/d5edb88c6adc4583900e64e8e4b76420
Autor:
Xiaofei Li, Rongrong Su, Peng Cheng, Heming Sun, Qinghang Meng, Taiyi Song, Mengpu Wei, Chen Zhang
Publikováno v:
Bulletin of the Polish Academy of Sciences: Technical Sciences, Vol 71, Iss 2 (2023)
With the continuous development of bridge technology, the condition assessment of large bridges has gradually attracted attention. Structural Health Monitoring (SHM) technology provides valuable information about a structure's existing health, keepin
Externí odkaz:
https://doaj.org/article/570503800de24ecb97176561f56c5378
Autor:
Stephanie L. K. Bowers, Qinghang Meng, Yasuhide Kuwabara, Jiuzhou Huo, Rachel Minerath, Allen J. York, Michelle A. Sargent, Vikram Prasad, Anthony J. Saviola, David Ceja Galindo, Kirk C. Hansen, Ronald J. Vagnozzi, Katherine E. Yutzey, Jeffery D. Molkentin
Publikováno v:
Cells, Vol 12, Iss 17, p 2174 (2023)
Rationale: The adult cardiac extracellular matrix (ECM) is largely comprised of type I collagen. In addition to serving as the primary structural support component of the cardiac ECM, type I collagen also provides an organizational platform for other
Externí odkaz:
https://doaj.org/article/bc1cebba95e0499bb087b9d6cd86552f
Publikováno v:
Applied Sciences, Vol 13, Iss 3, p 1348 (2023)
The number of bridges in operation has increased. Along with the increase in the length of time bridges are in service, the structural safety of the bridges also decreases. Bridge substructure is a key component of bridges, but there are few studies
Externí odkaz:
https://doaj.org/article/d9357e5ec00d45beaebdd19215995796
Autor:
Liang Chen, Zhimin Peng, Qinghang Meng, Maureen Mongan, Jingcai Wang, Maureen Sartor, Jing Chen, Liang Niu, Mario Medvedovic, Winston Kao, Ying Xia
Publikováno v:
Protein & Cell, Vol 7, Iss 5, Pp 338-350 (2016)
ABSTRACT Using forward and reverse genetics and global gene expression analyses, we explored the crosstalk between the IκB kinase β (IKKβ) and the transforming growth factor β (TGFβ) signaling pathways. We show that in vitro ablation of Ikkβ in
Externí odkaz:
https://doaj.org/article/3ec46300fa9044e9b73b987e7366ed1b
Autor:
Rizwan Yousaf, Qinghang Meng, Robert B. Hufnagel, Ying Xia, Chandrakala Puligilla, Zubair M. Ahmed, Saima Riazuddin
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 12, Pp 1543-1553 (2015)
MAP3K1 is a serine/threonine kinase that is activated by a diverse set of stimuli and exerts its effect through various downstream effecter molecules, including JNK, ERK1/2 and p38. In humans, mutant alleles of MAP3K1 are associated with 46,XY sex re
Externí odkaz:
https://doaj.org/article/e2732dad116f4b91be1430b4adbc5deb
Autor:
Bidur Bhandary, Qinghang Meng, Jeanne James, Hanna Osinska, James Gulick, Iñigo Valiente‐Alandi, Michelle A. Sargent, Md. Shenuarin Bhuiyan, Burns C. Blaxall, Jeffery D. Molkentin, Jeffrey Robbins
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 20 (2018)
Background Transforming growth factor beta (TGF‐β) is an important cytokine in mediating the cardiac fibrosis that often accompanies pathogenic cardiac remodeling. Cardiomyocyte‐specific expression of a mutant αB‐crystallin (CryABR120G), whic
Externí odkaz:
https://doaj.org/article/761a4cb3cf4649d4b6dd4661f7d03ab3
Autor:
Qinghang Meng, Bidur Bhandary, Hanna Osinska, Jeanne James, Na Xu, Kritton Shay‐Winkler, James Gulick, Monte S. Willis, Cynthia Lander, Jeffrey Robbins
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 9 (2017)
BackgroundCardiac stress can trigger production of a 40‐kDa peptide fragment derived from the amino terminus of the cardiac myosin‐binding protein C. Cardiac stress, as well as cMyBP‐C mutations, can trigger production of 1 such truncated prote
Externí odkaz:
https://doaj.org/article/dbc27fe9e550438e858ae6824cb461f1
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151869 (2016)
IkB kinase β (IKKβ) is a key signaling kinase for inflammatory responses, but it also plays diverse cell type-specific roles that are not yet fully understood. Here we investigated the role of IKKβ in the cornea using Ikkβ(ΔCS) mice in which the
Externí odkaz:
https://doaj.org/article/65c7e50ac55c453484ce3edb0e782df6
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87038 (2014)
Closure of an epithelium opening is a critical morphogenetic event for development. An excellent example for this process is the transient closure of embryonic eyelid. Eyelid closure requires shape change and migration of epithelial cells at the tip
Externí odkaz:
https://doaj.org/article/9eb4d3fac6d8484c8da7997fd2ddbd32