Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Qinghang Liu"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Ferroptosis is a new form of regulated necrosis characterized by iron-dependent lipid peroxidation, leading to irreparable lipid damage, membrane permeabilization, and necrotic cell death. Ferroptosis has recently been implicated in the pathogenesis
Externí odkaz:
https://doaj.org/article/cd54a8ecda50445c976df1811b129870
Autor:
Yi Chen, Xiaoyun Guo, Yachang Zeng, Xiaoliang Mo, Siqi Hong, Hui He, Jing Li, Sulail Fatima, Qinghang Liu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Oxidative stress has been shown to induce cell death in a wide range of human diseases including cardiac ischemia/reperfusion injury, drug induced cardiotoxicity, and heart failure. However, the mechanism of cell death induced by oxidative s
Externí odkaz:
https://doaj.org/article/e4e2e10e174d425fb5f650ac07f59e86
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
The cardiac calcium channel CaV1.2 conducts L-type calcium currents that initiate excitation-contraction coupling and serves as a crucial mediator of β-adrenergic regulation of the heart. We evaluated the inotropic response of mice with mutations in
Externí odkaz:
https://doaj.org/article/541ae4a3365a4e538aa82c219df0f671
Autor:
Dominic P. Del Re, Qinghang Liu
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 2, Iss , Pp 100019- (2022)
Externí odkaz:
https://doaj.org/article/29b7dde30d7440e79e5cac7511264b3a
Autor:
Haifeng Yin, Xiaoyun Guo, Yi Chen, Yachang Zeng, Xiaoliang Mo, Siqi Hong, Hui He, Jing Li, Rachel Steinmetz, Qinghang Liu
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 4 (2022)
Mutations in TGF-β–activated kinase 1 binding protein 2 (TAB2) have been implicated in the pathogenesis of dilated cardiomyopathy and/or congenital heart disease in humans, but the underlying mechanisms are currently unknown. Here, we identified a
Externí odkaz:
https://doaj.org/article/5e9d1cbdf24d454789edd6a43bae9d96
Autor:
Wei Wei, Rongxian Li, Qinghang Liu, Vidya Devanathadesikan Seshadri, Vishnu Priya Veeraraghavan, Krishna Mohan Surapaneni, Thamaraiselvan Rengarajan
Publikováno v:
Arabian Journal of Chemistry, Vol 14, Iss 8, Pp 103238- (2021)
Background: Colorectal cancer (CRC) is a frequently diagnosed cancer that primarily affects the digestive system and an imperative cause of mortalities worldwide. Objective: In this work, we formulated the Tin oxide-Sodium alginate-Polyethylene glyco
Externí odkaz:
https://doaj.org/article/40332831eec14764bbdfba5954155596
Autor:
Theresa Aliwarga, Xiaoyun Guo, Eric A. Evangelista, Rozenn N. Lemaitre, Nona Sotoodehnia, Sina A. Gharib, Darryl C. Zeldin, Qinghang Liu, Rheem A. Totah
Publikováno v:
Biomedicines, Vol 8, Iss 6, p 144 (2020)
Elevated cis-epoxyeicosatrienoic acids (EETs) are known to be cardioprotective during ischemia-reperfusion injury in cardiomyocyte-specific overexpressing cytochrome P450 2J2 (CYP2J2) transgenic (Tr) mice. Using the same Tr mice, we measured changes
Externí odkaz:
https://doaj.org/article/ed088bee633645eaac5f1e886ef9aaad
Publikováno v:
Frontiers in Physiology; 2024, p1-13, 13p
Autor:
Jing Li, Qinghang Liu, Yachang Zeng, Siqi Hong, Rachel Steinmetz, Xiaoyun Guo, Lei Li, Yi Chen, Xiaoliang Mo, Hui He
Publikováno v:
Free Radic Biol Med
In this study, we identified an unexpected pro-cell death role for NFκB in mediating oxidative stress-induced necrosis, and provide new mechanistic evidence that NFκB, in cooperation with HDAC3, negatively regulates Nrf2-ARE anti-oxidative signalin
Publikováno v:
J Mol Cell Cardiol
Cell death is a crucial event underlying cardiac ischemic injury, pathological remodeling, and heart failure. Unlike apoptosis, necrosis had long been regarded as a passive and unregulated process. However, recent studies demonstrate that a significa