Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Qingguo Ruan"'
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-13 (2023)
Abstract The integrity of the corneal epithelium is essential for the maintenance of the physiological function of the cornea. Studies have found that inflammation greatly delays corneal wound healing. NF-κB c-Rel is preferentially expressed by immu
Externí odkaz:
https://doaj.org/article/a7ad63f1dde642aba87f3019588d499e
Autor:
Ruiling Liu, Cuilian Liu, Xiaozhen He, Peng Sun, Bin Zhang, Haoran Yang, Weiyun Shi, Qingguo Ruan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The microRNA miR-21 is induced in the islets of patients with glucose intolerance and diabetic mice. Here the authors report that deletion of miR-21 in pancreatic β-cells impairs glucose-stimulated insulin secretion via reduced glucose uptake, while
Externí odkaz:
https://doaj.org/article/19d9b6534cdc44a3a0c67c6214ac0b6b
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Regulatory T cells (Tregs) are considered important for controlling the onset and development of autoimmune disease. Although studies have shown that miR-21 is expressed at higher levels in Treg cells, it remains largely elusive whether miR-21 regula
Externí odkaz:
https://doaj.org/article/cfadb639ae56419a8365902fee7f7c14
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Experimental autoimmune uveitis (EAU) is a CD4+ T cell–mediated organ-specific autoimmune disease and has been considered as a model of human autoimmune uveitis. Dracocephalum heterophyllum (DH) is a Chinese herbal medicine used in treating hepatit
Externí odkaz:
https://doaj.org/article/2ee76bc647d0452b9dfe1166d80cce6d
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Autoimmune diseases are a physiological state wherein immune responses are directed against and damage the body's own tissues. Cytokines secreted by infiltrated inflammatory cells contribute to the pathogenesis of autoimmune diseases. TIPE2, one of t
Externí odkaz:
https://doaj.org/article/486e3f5b068f4d9ba2d477463d29a535
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170666 (2017)
Macrophages play important roles in the regulation of the innate and adaptive immune responses. Classically activated macrophages and alternatively activated macrophages are the two major forms of macrophages and have opposing functionalities. Tumor
Externí odkaz:
https://doaj.org/article/24496cd52d5944378e55dddc71f39473
Autor:
Xiaochun Wan, Xiaolu Yang, Youhai H. Chen, Qingguo Ruan, Junxin Li, Qian Chen, Xin Li, Guizhong Zhang
Supplementary Figures with legends - Supplementary Figures S1 through S4. (1) Supplementary Figure S1 shows that upregulation of CD317 expression correlates with tumorigenesis (supplementary to fig. 1). (2) Supplementary Figure S2 shows CD317 promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef2b9c0e931071832bb1809850e76f8
https://doi.org/10.1158/0008-5472.22424024.v1
https://doi.org/10.1158/0008-5472.22424024.v1
Autor:
Xiaochun Wan, Xiaolu Yang, Youhai H. Chen, Qingguo Ruan, Junxin Li, Qian Chen, Xin Li, Guizhong Zhang
EGFR regulates various fundamental cellular processes, and its constitutive activation is a common driver for cancer. Anti-EGFR therapies have shown benefit in cancer patients, yet drug resistance almost inevitably develops, emphasizing the need for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a74597051914f0b687b007a2aa9ea86
https://doi.org/10.1158/0008-5472.c.6511661.v1
https://doi.org/10.1158/0008-5472.c.6511661.v1
Autor:
Qingguo Ruan, Hao Chi, Shaowen Wang, Songmei Zhang, Zhijiao Wu, Jiang Bian, Weiyun Shi, Tingting Fan, Xiaozhen He, Ting Wang, Jijun Sun
Publikováno v:
American Journal of Transplantation. 21:3858-3870
The relevance of Tregs in the induction of tolerance against corneal allografts has been well established. Although it is well known that the conversion of Tregs into effector-like cells contributes to the loss of corneal immune privilege, the underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134addba0eb554ba5ed0e2fc0d49258b
https://doi.org/10.1111/ajt.16760
https://doi.org/10.1111/ajt.16760
Autor:
Yunhan Ma, Yan Yang, Helong Dai, Changxiu Yan, Shengnan Yu, Shuaishuai Zhang, Zeyang Lin, Jinfeng Chen, Gaoyi Yu, Jing Zhang, Ping Yin, Jianhong Lu, Chunyan Shi, Zhijian Ye, Qingguo Ruan, Zhongquan Qi, Guohong Zhuang
Publikováno v:
Clinical Immunology. 252:109636
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71aea44239bf2a2957a58b3ede4ad1f9
https://doi.org/10.1016/j.clim.2023.109636
https://doi.org/10.1016/j.clim.2023.109636