Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Qingge Guo"'
Publikováno v:
JMIR Medical Education, Vol 10, Pp e52784-e52784 (2024)
Abstract BackgroundWith the increasing application of large language models like ChatGPT in various industries, its potential in the medical domain, especially in standardized examinations, has become a focal point of research. ObjectiveThe aim of
Externí odkaz:
https://doaj.org/article/7fbe0f24610842deab04cf87eeb6a15d
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background TikTok is emerging as a vital platform for health information dissemination. Despite myopia being a global public health issue, the high-quality myopia information shared by health educators often fails to go viral. It is imperati
Externí odkaz:
https://doaj.org/article/209abac5143b41e8a90a2428a4892d71
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2020 (2024)
Increased or altered mitochondrial ROS production in the retinal ganglion cells is regarded as the chief culprit of the disease-causing Leber’s hereditary optic neuropathy (LHON). SkQ1 is a rechargeable mitochondria-targeted antioxidant with high s
Externí odkaz:
https://doaj.org/article/9691a87f163a4d33a24188a613c504f6
Autor:
Keke Liang, Xiaohuan Li, Qingge Guo, Jianjun Ma, Hongqi Yang, Yongyan Fan, Dawei Yang, Xiaoxue Shi, Zonghan She, Xuelin Qi, Qi Gu, Siyuan Chen, Jinhua Zheng, Dongsheng Li
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106379- (2024)
Background: Cognitive impairment is a serious nonmotor symptom in patients with Parkinson's disease (PD). Currently, there are few studies investigating the relationship of serum markers and retinal structural changes with cognitive function in PD. O
Externí odkaz:
https://doaj.org/article/94cf5a0051a54cf096b267d9de33d10a
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundCone-rod dystrophy (CORD) caused by pathogenic variants in CFAP410 is a very rare disease. The mechanisms by which the variants caused the disease remained largely unknown. CFAP410 pathogenic variants were identified in a cone-rod dystrophy
Externí odkaz:
https://doaj.org/article/58a93b832274402aa9ed0521d249ccde
Autor:
Lin Yang, Xiuxiu Jin, Ya Li, Qingge Guo, Mingzhu Yang, Ya You, Shun Yao, Xiaoli Zhang, Zhongfeng Wang, Bo Lei
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Dominant optic atrophy (DOA) is the most common hereditary optic neuropathy. Although DOA is caused by mutations in several genes, there are still many cases that have not been diagnosed or misdiagnosed. Herein, we present a large family of
Externí odkaz:
https://doaj.org/article/524bf0d746a9487aa40ef74f5a0eabd5
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
BackgroundIn Leber’s hereditary optic neuropathy (LHON), mtDNA mutations mediate mitochondrial dysfunction and apoptosis of retinal ganglion cells. Mitochondrial superoxide dismutase 2 (SOD2) is a crucial antioxidase against reactive oxygen species
Externí odkaz:
https://doaj.org/article/c7982033fc364a8db280dd289b4295b4
Autor:
Shun Yao, Qingru Zhou, Mingzhu Yang, Ya Li, Xiuxiu Jin, Qingge Guo, Lin Yang, Fangyuan Qin, Bo Lei
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Heterogeneity is a major feature of Leber's hereditary optic neuropathy (LHON) and has a significant impact on the manifestation and diagnosis of the disease. This study explored whether multiple variations in mitochondrial genes were associated with
Externí odkaz:
https://doaj.org/article/83f95aea19ad472d9879997e80f8fbda
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Purpose: X-linked juvenile retinoschisis (XLRS), caused by mutations in the RS1 gene, is an X-linked recessive inherited disease that typically involves both eyes in the first 2 decades of life. Recently, the phenotype heterogeneity of this condition
Externí odkaz:
https://doaj.org/article/05954bb66d08465e94f52925363b1e2b
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Purpose: To study the association between axial length (AL) and the thickness of the lens, retina, choroid, and cone density with swept-source optical coherence tomography (SS-OCT) and an adaptive optics (AO) fundus camera.Design: A prospective cross
Externí odkaz:
https://doaj.org/article/5aef781a27aa4ca2957b5eeeb7ddc87a