Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Qingfeng He"'
Publikováno v:
Shipin gongye ke-ji, Vol 45, Iss 9, Pp 159-167 (2024)
The objective of this study was to investigate the optimal preparation process and digestive properties of sulforaphane from Raphanus sativus seeds prepared by enzymatic method. Single factor experiment and response surface methodology were employed
Externí odkaz:
https://doaj.org/article/45bd9cdff13346c3b3c401f7b842e788
Autor:
Nuo Xu, Yufei Shi, Yixue Wang, Wenyao Mak, Wenyu Yang, Kar Weng Ng, Yue Wu, Zhijia Tang, Qingfeng He, Gangfeng Yan, Xiaoqiang Xiang, Xiao Zhu
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 819 (2024)
Background: Caspofungin is an echinocandin antifungal agent commonly used as the first-line therapy for invasive candidiasis, salvage therapy for invasive aspergillosis, and empirical therapy for presumed fungal infections. Pharmacokinetic (PK) varia
Externí odkaz:
https://doaj.org/article/bf6ebeaa7c4e4fc68a5843de4c6596cb
Autor:
Anning Li, Wen Yao Mak, Tingyi Ruan, Fang Dong, Nan Zheng, Meng Gu, Wei Guo, Jingye Zhang, Haoxuan Cheng, Canjun Ruan, Yufei Shi, Yannan Zang, Xuequan Zhu, Qingfeng He, Xiaoqiang Xiang, Gang Wang, Xiao Zhu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Amisulpride is primarily eliminated via the kidneys. Given the clear influence of renal clearance on plasma concentration, we aimed to explicitly examine the impact of renal function on amisulpride pharmacokinetics (PK) via population P
Externí odkaz:
https://doaj.org/article/7c87345881964870a4c779fa7ade6f3b
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 12, Pp 4271-4286 (2022)
The outbreak and spread of coronavirus disease 2019 (COVID-19) highlighted the importance and urgency of the research and development of therapeutic drugs. Very early into the COVID-19 pandemic, China has begun developing drugs, with some notable pro
Externí odkaz:
https://doaj.org/article/f5d4df7903c341d2b771a135623232b7
Autor:
Meng Gu, Anning Li, Wenyao Mak, Fang Dong, Nuo Xu, Jingye Zhang, Yufei Shi, Nan Zheng, Zhijia Tang, Qingfeng He, Canjun Ruan, Wei Guo, Xiaoqiang Xiang, Chuanyue Wang, Bing Han, Xiao Zhu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The sublingual combination of buprenorphine (BUP) and naloxone (NLX) is a new treatment option for opioid use disorder (OUD) and is effective in preventing drug abuse. This study aimed to explore rational dosing regimen for OUD patients in China via
Externí odkaz:
https://doaj.org/article/933daccccc2444fb91a462f11a434e0f
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: We aimed to evaluate alirocumab- and evolocumab-related adverse events (AEs) in real-world compared with all other drugs, overall and by gender and age subgroups; we also aimed to compare their risks of cognitive impairment, musculoskeleta
Externí odkaz:
https://doaj.org/article/ff044fc14c454f87be9459d9221a56bd
Autor:
Wenyu Yang, Wenyao Mak, Amanda Gwee, Meng Gu, Yue Wu, Yufei Shi, Qingfeng He, Xiaoqiang Xiang, Bing Han, Xiao Zhu
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1801 (2023)
Background: Ganciclovir and valganciclovir are used for prophylaxis and treatment of cytomegalovirus infection. However, there is great interindividual variability in ganciclovir’s pharmacokinetics (PK), highlighting the importance of individualize
Externí odkaz:
https://doaj.org/article/6825552b4888401187a2d095f73dbad2
Autor:
Jianya Deng, Xinyan Liu, Yiming Wang, Jieyang Fan, Li Yang, Jiamin Duan, Yongfang Yuan, Peishu Lan, Zhuoxuan Shan, Junfeng Xiong, Wenyu Peng, Qingfeng He, Yajie Chen, Xiaoxu Fu
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
IntroductionSleep health is an important part of health and has become a common concern of society. For anxiety insomnia, the commonly used clinical therapies have limitations. Alternative and complementary therapy is gradually rising and showing rem
Externí odkaz:
https://doaj.org/article/8652a704cc7f49a3a9c05fe442309b97
Autor:
Yawen Yuan, Qingfeng He, Shunguo Zhang, Min Li, Zhijia Tang, Xiao Zhu, Zheng Jiao, Weimin Cai, Xiaoqiang Xiang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pharmacokinetic characterization plays a vital role in drug discovery and development. Although involving numerous laboratory animals with error-prone, labor-intensive, and time-consuming procedures, pharmacokinetic profiling is still irreplaceable i
Externí odkaz:
https://doaj.org/article/52c20929021048a6b879da7e3931c526
Autor:
Yawen Yuan, Zhihong Li, Ke Wang, Shunguo Zhang, Qingfeng He, Lucy Liu, Zhijia Tang, Xiao Zhu, Ying Chen, Weimin Cai, Chao Peng, Xiaoqiang Xiang
Publikováno v:
Molecules, Vol 28, Iss 2, p 837 (2023)
Novel furoxan/coumarin hybrids were synthesized, and pharmacologic studies showed that the compounds displayed potent antiproliferation activities via downregulating both the phosphatidylinositide 3-kinase (PI3K) pathway and the mitogen-activated pro
Externí odkaz:
https://doaj.org/article/945a914e50864c6e8c838711e18887b0