Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Qingfei Pan"'
Autor:
Ming Shao, Qingfei Pan, Haiyan Tan, Jing Wu, Ha Won Lee, Andrew D. Huber, William C. Wright, Ji-Hoon Cho, Jiyang Yu, Junmin Peng, Taosheng Chen
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101079- (2024)
CYP3A5 is a cytochrome P450 (CYP) enzyme that metabolizes drugs and contributes to drug resistance in cancer. However, it remains unclear whether CYP3A5 directly influences cancer progression. In this report, we demonstrate that CYP3A5 regulates gluc
Externí odkaz:
https://doaj.org/article/9ad3267c458a4173bd3a65ec2f9de8f9
Autor:
Xinran Dong, Liang Ding, Andrew Thrasher, Xinge Wang, Jingjing Liu, Qingfei Pan, Jordan Rash, Yogesh Dhungana, Xu Yang, Isabel Risch, Yuxin Li, Lei Yan, Michael Rusch, Clay McLeod, Koon-Kiu Yan, Junmin Peng, Hongbo Chi, Jinghui Zhang, Jiyang Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Many signaling and other genes known as “hidden” drivers may not be genetically or epigenetically altered or differentially expressed at the mRNA or protein levels, but, rather, drive a phenotype such as tumorigenesis via post-translatio
Externí odkaz:
https://doaj.org/article/14c0f151bd884b528e374cdf295c69fb
Autor:
Anthony Brown, Qingfei Pan, Li Fan, Emilie Indersie, Cheng Tian, Nikolai Timchenko, Liyuan Li, Baranda S. Hansen, Haiyan Tan, Meifen Lu, Junmin Peng, Shondra M. Pruett-Miller, Jiyang Yu, Stefano Cairo, Liqin Zhu
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
In hepatoblastoma, the RRM2 subunit of ribonucleotide reductase is associated with disease progression, but in response to chemotherapy, subunit switching favours the less active RRM2B subunit which supports hepatoblastoma cell survival and relapse.
Externí odkaz:
https://doaj.org/article/ae5989f069384abbaef73e2aa057eb83
Autor:
Fengzhen Cui, Qingfei Pan, Siyi Wang, Faming Zhao, Runxin Wang, Tingting Zhang, Yaying Song, Jun He, Haolin Zhang, Qiang Weng, Yang Jin, Wei Xia, Yuanyuan Li, Guo‐Yuan Yang, Winnok H. De Vos, Jean‐Pierre Timmermans, Shunqing Xu, Yaohui Tang, Xia Sheng
Publikováno v:
Advanced Science, Vol 8, Iss 23, Pp n/a-n/a (2021)
Abstract Benzophenones are widely supplemented in personal care products, but little is known about its neurodevelopmental toxicity. The previous epidemiological study discovered a negative correlation between maternal exposure to a benzophenone meta
Externí odkaz:
https://doaj.org/article/9ff51389b7e84628bbd7bcfc0125f273
Autor:
Douglas K. Marks, Robyn D. Gartrell, Margueritta El Asmar, Shuobo Boboila, Thomas Hart, Yan Lu, Qingfei Pan, Jiyang Yu, Hanina Hibshoosh, Hua Guo, Eleni Andreopoulou, Lisa Wiechmann, Katherine Crew, Joseph Sparano, Dawn Hershman, Eileen Connolly, Yvonne Saenger, Kevin Kalinsky
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: The PI3K/Akt/mTOR pathway in part impacts tumorigenesis through modulation of host immune activity. To assess the effects of Akt inhibition on the tumor micro-environment (TME), we analyzed tumor tissue from patients with operable hormone
Externí odkaz:
https://doaj.org/article/161752bec1d44d66a615bab9381ecca5
Autor:
Miaomiao Li, Xu Zhao, Wei Wang, Hailing Shi, Qingfei Pan, Zhike Lu, Sonia Peña Perez, Rajikala Suganthan, Chuan He, Magnar Bjørås, Arne Klungland
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-16 (2018)
Abstract Background N 6 -methyladenosine (m6A) modification in mRNAs was recently shown to be dynamically regulated, indicating a pivotal role in multiple developmental processes. Most recently, it was shown that the Mettl3-Mettl14 writer complex of
Externí odkaz:
https://doaj.org/article/7f9dd8ef00aa417ab2066fa164af8e4a
Autor:
Qingfei Pan, Xiaomin Lou, Ju Zhang, Yinghui Zhu, Fuqiang Li, Qiang Shan, Xianwei Chen, Yingying Xie, Siyuan Su, Hanfu Wei, Liang Lin, Lin Wu, Siqi Liu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Mouse model induced by azoxymethane (AOM) and dextran sodium sulfate (DSS) is generally accepted as an ideal object to study on the carcinogenesis mechanisms of human colorectal cancer (CRC). The genomic responses to the AOM/DSS treatment in
Externí odkaz:
https://doaj.org/article/f86b27beca4d48a7b6030cb5ccdfd5d0
Autor:
Qingfei Pan, Xiaomin Lou, Ju Zhang, Yinghui Zhu, Fuqiang Li, Qiang Shan, Xianwei Chen, Yingying Xie, Siyuan Su, Hanfu Wei, Liang Lin, Lin Wu, Siqi Liu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-1 (2017)
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
Externí odkaz:
https://doaj.org/article/ac5579e15d484a2dade59d1a8d9102de
Autor:
Li Fan, Qingfei Pan, Wentao Yang, Selene C. Koo, Cheng Tian, Liyuan Li, Meifen Lu, Anthony Brown, Bensheng Ju, John Easton, Sarangarajan Ranganathan, Soona Shin, Alexander Bondoc, Jun J. Yang, Jiyang Yu, Liqin Zhu
Publikováno v:
Hepatology. 76:1275-1290
Hepatoblastoma (HB) is the most common pediatric liver cancer. Its predominant occurrence in very young children led us to investigate whether the neonatal liver provides a protumorigenic niche to HB development.HB development was compared between or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a70a83c74b35257b4076ef7a2de0f5a
https://doi.org/10.1002/hep.32412
https://doi.org/10.1002/hep.32412
Autor:
Jiyang Yu, Liang Ding, Hao Shi, Chenxi Qian, Chad Burdyshaw, Joao Veloso, Alireza Khatamian, Qingfei Pan, Yogesh Dhungana, Zhen Xie, Isabel Risch, Xu Yang, Xin Huang, Lei Yan, Michael Rusch, Michael Brewer, Koon-Kiu Yan, Hongbo Chi
Publikováno v:
bioRxiv
The sparse nature of single-cell omics data makes it challenging to dissect the wiring and rewiring of the transcriptional and signaling drivers that regulate cellular states. Many of the drivers, referred to as “hidden drivers”, are difficult to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ab6a33393166f6f7c35d2ad5e60dc4
https://doi.org/10.1101/2023.01.26.523391
https://doi.org/10.1101/2023.01.26.523391
