Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Qingfa Chen"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Raman scattering is an inelastic light scattering that occurs in a manner reflective of the molecular vibrations of molecular structures and chemical conditions in a given sample of interest. Energy changes in the scattered light can be assessed to d
Externí odkaz:
https://doaj.org/article/75333e0377384b15afde845c49dfc979
Autor:
Ting Gui, Qingfa Chen, Jiangsong Li, Ke Lu, Chen Li, Bin Xu, Yang Chen, Jingwen Men, Gerd A. Kullak-Ublick, Weihua Wang, Zhibo Gai
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Chronic kidney disease (CKD) can lead to significant elevation of 1-deoxysphingolipids (1-deoxySL). The increase of 1-deoxySL in turn can result in mitochondrial damage and oxidative stress, which can cause further progression of CKD.Me
Externí odkaz:
https://doaj.org/article/7e9c1537b3804c118fb2b076e867cfd3
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundThe function of angiogenesis-related genes (ARGs) in lung adenocarcinoma (LUAD) remains poorly documented. This study was designed to reveal ARGs in LUAD and related networks.MethodsWe worked with sequencing data and clinical information pe
Externí odkaz:
https://doaj.org/article/d2441513f14046a5bc19aef16fa4c65b
Autor:
Xianjie Lu, Wei Wang, Yanming Liu, Na Song, Mengpeng Li, Xin Mu, Nan Zhang, Qingfa Chen, Licheng Jiang, Xianglin Kong, Peng Sun, Jiabei Tong, Yunping Zhang, Jingtao Li, Shengjun Ma, Fabin Han
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102685- (2022)
Mutations in VPS13 gene have been recently reported as a genetic cause of Parkinson's disease (PD). In this study, we isolated the skin fibroblasts from a PD patient harboring VPS13A gene mutation (c. 4282_4289delinsA) and reprogrammed the fibroblast
Externí odkaz:
https://doaj.org/article/332c6bbf1a8544b9ba4ce0df5431b835
Autor:
Chao Han, Juan Zheng, Fengyi Wang, Qingyang Lu, Qingfa Chen, Ankang Hu, Michele Visentin, Gerd A. Kullak-Ublick, Zhibo Gai, Lei Chu
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
Organic cation transporter 2 (OCT2), encoded by the SLC22A2 gene, is the main cation transporter on the basolateral membrane of proximal tubular cells. OCT2 facilitates the entry step of the vectorial transport of most cations from the peritubular sp
Externí odkaz:
https://doaj.org/article/fd4418ae59e748cea0226c344a7f7124
Autor:
Chao Chen, Qingfa Chen, Yan Liu, Chongyang Zhang, Kaixiang Zhu, Xue Li, Haitao Xie, Rui Zhang
Publikováno v:
Journal of Neurorestoratology, Vol 8, Iss 2, Pp 93-103 (2020)
Background and Objective:Parkinson’s disease (PD) is a common neurodegenerative disease. Previous studies have demonstrated the effect of cell-based therapies, but their clinical efficacy and safety have not been evaluated. This review protocol aim
Externí odkaz:
https://doaj.org/article/c4810c69c52945cbbd3080e03bd6eb85
Autor:
Dongfeng Sun, Qingfa Chen, Zhibo Gai, Fengxia Zhang, Xiaoqing Yang, Wensi Hu, Chengyu Chen, Guangjie Yang, Severin Hörmann, Gerd. A. Kullak-Ublick, Michele Visentin
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Esophageal cancer is the ninth most common malignancy worldwide, ranking sixth in mortality. Platinum-based chemotherapy is commonly used for treating locally advanced esophageal cancer, yet it is ineffective in a large portion of patients. There is
Externí odkaz:
https://doaj.org/article/dd4999781f954e039736b5cf2d31f28f
Publikováno v:
The Scientific World Journal, Vol 2021 (2021)
Background. To study the effects of z-guggulsterone on gastric cancer cell apoptosis and the mechanism related. Materials and Methods. Human gastric tumor SGC-7901 cells and GES-1 normal epithelial cells were treated with z-guggulsterone (0–75 μM)
Externí odkaz:
https://doaj.org/article/26db762ef49146258bb439ffaa49cfc1
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 128, Iss , Pp 110306- (2020)
Objective: Regular consumption of n-3 polyunsaturated fatty acids is associated with decreased cardiovascular morbidity and mortality. This study assessed the therapeutic effect of docosahexaenoic acid (DHA) in palmitic acid (PA)-induced cytotoxicity
Externí odkaz:
https://doaj.org/article/b29fdfc404714e9f8af3689b4bc0951b
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Neural progenitor cells (NPCs) have great potentials in cell replacement therapy for neurodegenerative diseases, such as Alzheimer’s disease (AD), by promoting neurogenesis associated with hippocampal memory improvement. Ephrin receptors and angiog
Externí odkaz:
https://doaj.org/article/f6ff4b6e5eb7486faf2762b4375c1ae8