Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Qingde, Zhou"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Cutaneous melanoma (CM) is a highly malignant tumor originating from melanocytes, and its metastasis and recurrence are the major causes of death in CM patients. PANoptosis is a newly defined inflammatory programmed cell death that crosstalk
Externí odkaz:
https://doaj.org/article/6f6a83b78b074c25932aa4417f40c8c3
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Acidic fibroblast growth factor (aFGF) is a promising regulator of glucose with no adverse effects of hypoglycemia. Previous researches revealed that aFGF mediated adipose tissue remodeling and insulin sensitivity. These findings supported rh-aFGF135
Externí odkaz:
https://doaj.org/article/f0bd806196554642b1bfcac00a38844c
Autor:
Huiyun Wang, Baogang Xie, Lan Lan, Jun Wang, Qingde Zhou, Xiaoyue Du, Nan Jin, Pan Jiang, Wei Wang, Xinchang Xu
Publikováno v:
Biomedical Chromatography. 37
Autor:
Qingde Zhou, Allen Yen, Grzegorz Rymarczyk, Hirohide Asai, Chelsea Trengrove, Nadine Aziz, Michael T. Kirber, Gustavo Mostoslavsky, Tsuneya Ikezu, Benjamin Wolozin, Victoria M. Bolotina
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
PLA2g6 regulates store-operated Ca2+ entry and is linked to Parkinson’s disease. Here, Zhou et al find faulty PLA2g6-dependent Ca2+signaling in idiopathic PD patients, and show that its impairment triggers autophagic dysfunction and loss of dopamin
Externí odkaz:
https://doaj.org/article/33e1f0f92a0c4245b5c7415b37aee723
Autor:
Xiaojie Wang, Xiaokun Li, Qingde Zhou, Xuanxin Yang, Wenqing Li, Zhen Huang, Qi Hui, Gaozhong Cao, Bingjie Yu, Lufeng Hu, Rongshuai Yang, Shucai Pang, Li Zhang
Publikováno v:
ACS biomaterials scienceengineering. 4(5)
Hydrogels are excellent drug delivery carriers with excellent ductility. Here, we report the design of a higher biostability of a recombinant human acidic fibroblast growth factor (rh-aFGF) carbomer hydrogel formulation. To verify the optimality of t
Autor:
Qingde Zhou, Jianxiang Gong, Jianing Bi, Xuanxin Yang, Li Zhang, Chao Lu, Lijia Li, Min Chen, Jianqiu Cai, Rongshuai Yang, Xiaokun Li, Zhiming Li, Xiaojie Wang
Publikováno v:
The Journal of investigative dermatology. 142(7)
Hypertrophic scar is a common complication of burns, skin trauma, and postoperative trauma, which involves excessive proliferation of fibroblasts and accumulation of a large amount of disorganized collagen fibers and extracellular matrix. KGF-2 plays
Autor:
Jianing Bi, Jianxiang Gong, Min Chen, Wenzhe Sun, Rongshuai Yang, Yang Xuanxin, Tongzhou Huang, Xiaokun Li, Chao Lu, Qingde Zhou, Qi Hui, Yingying Zheng, Wang Xiaojie, Lijia Li
Publikováno v:
BMJ Open Diabetes Research & Care
ObjectiveThe present study focused on the development of a poloxamer 407 thermosensitive hydrogel loaded with keratinocyte growth factor-2 (KGF-2) and fibroblast growth factor-21 (FGF-21) as a therapeutic biomaterial in a scald-wound model of type-2
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15613 (2010)
Periodontitis is the most common human infection affecting tooth-supporting structures. It was shown to play a role in aggravating atherosclerosis. To deepen our understanding of the pathogenesis of this disease, we exposed human macrophages to an or
Externí odkaz:
https://doaj.org/article/d3a031e66eb94c9baf5ff521718146d1
Autor:
Jianqiu Cai, Xiaojie Wang, Ruide Guo, Naveed Ahmad, Xuanxin Yang, Qingde Zhou, Zhitao Wang, Qi Chen, Rongshuai Yang, Wenqing Li, Qi Hui
Publikováno v:
Cornea. 38(11)
Purpose Basic fibroblast growth factor (bFGF) is an effective drug for corneal injury. However, the explicit role of bFGF in corneal scar formation still remains unclear. Keratinocyte growth factor-2 (KGF-2) is associated with the treatment of wound
Autor:
Xiaojie Wang, Yadong Huang, Xiaokun Li, Qingde Zhou, Jinghang Li, Wenqing Li, Jianqiu Cai, Qi Hui
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 103
Keratinocyte growth factor −2 promotes corneal repair. Its mechanism of action involves regulating regeneration and migration of corneal cells, as well as activating corneal limbal stem cells. However, KGF-2 being a carcinogenic growth factor and i