Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Qing-tong Zhou"'
Autor:
Sanaz Darbalaei, Ru-lue Chang, Qing-tong Zhou, Yan Chen, An-tao Dai, Ming-wei Wang, De-hua Yang
Publikováno v:
Acta Pharmacologica Sinica. 44:421-433
The paradigm of one drug against multiple targets, known as unimolecular polypharmacology, offers the potential to improve efficacy while overcoming some adverse events associated with the treatment. This approach is best exemplified by targeting two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64b9af6ceb406c6efeb3674396ff121
https://doi.org/10.1038/s41401-022-00962-y
https://doi.org/10.1038/s41401-022-00962-y
Publikováno v:
Acta Pharmacol Sin
Nonalcoholic steatohepatitis (NASH), as a severe form of nonalcoholic fatty liver disease (NAFLD), is characterized by liver steatosis, inflammation, hepatocellular injury and different degrees of fibrosis. The pathogenesis of NASH is complex and mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f497742ba5c2179623cac352d557d8d1
https://doi.org/10.1038/s41401-021-00836-9
https://doi.org/10.1038/s41401-021-00836-9
Autor:
Wen-sheng Yang, Jing-lin Wang, Wei Wu, Guang-fei Wang, Jun Yan, Qing Liu, Xiao-yan Wu, Qing-tong Zhou, De-hua Yang, Ming-Wei Wang, Zhi-ping Li
Publikováno v:
Acta pharmacologica Sinica.
Inflammatory bowel disease (IBD) is a global health burden whose existing treatment is largely dependent on anti-inflammatory agents. Despite showing some therapeutic actions, their clinical efficacy and adverse events are unacceptable. Resolution as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6d4025ffba61fafc242e1fbe071eb6
https://pubmed.ncbi.nlm.nih.gov/35840658
https://pubmed.ncbi.nlm.nih.gov/35840658
Autor:
Jie Li, Yan Zhou, Guy Eelen, Qing-tong Zhou, Wen-bo Feng, Viktorija Labroska, Fen-fen Ma, Hui-ping Lu, Mieke Dewerchin, Peter Carmeliet, Ming-wei Wang, De-hua Yang
Publikováno v:
Acta pharmacologica Sinica.
The growth of solid tumors depends on tumor vascularization and the endothelial cells (ECs) that line the lumen of blood vessels. ECs generate a large fraction of ATP through glycolysis, and elevation of their glycolytic activity is associated with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c0ffc7cbebb79321670f0f5e936244
https://pubmed.ncbi.nlm.nih.gov/36114272
https://pubmed.ncbi.nlm.nih.gov/36114272
Publikováno v:
Chinese Journal of Chemical Physics (1674-0068); 6/27/2016, Vol. 29 Issue 3, p374-380, 7p