Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Qing-Zhi Gao"'
Autor:
Yunxia Yuan, Yuheng Ma, Gang Wu, Li Ai, Yongqiang Zhu, Xinrong Zhu, Yuejie Li, Xin Zhao, Jie Yang, Qing-Zhi Gao, Yang Hu
Publikováno v:
Journal of medicinal chemistry. 52(14)
New series of dipeptidyl boronate inhibitors of 20S proteasome were designed and synthesized. The comprehensive understanding of the SAR was obtained by utilizing the variation of four substituents. From the screened compounds in enzyme, novel inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223154a314a47585fc568854fd250202
https://pubmed.ncbi.nlm.nih.gov/19537716
https://pubmed.ncbi.nlm.nih.gov/19537716
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 43(3)
A2B adenosine receptor is involved in the control of mast cell degranulation, interleukin-8 synthesis and cell growth. A2B adenosine receptor antagonists may serve as novel drugs for asthma, Alzheimer' s disease, cystic fibrosis and type-II diabetes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed5e7eef4a9201cfed76bd395ea1ef02
https://pubmed.ncbi.nlm.nih.gov/18630258
https://pubmed.ncbi.nlm.nih.gov/18630258
Publikováno v:
European journal of medicinal chemistry. 44(4)
Three-dimensional quantitative structure-activity relationship (3D-QSAR) studies were performed for a series of dipeptide boronate proteasome inhibitors using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a620c1e1fe9e57efe5fd8674fb0cf173
https://pubmed.ncbi.nlm.nih.gov/18771818
https://pubmed.ncbi.nlm.nih.gov/18771818