Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Qing-Yun Chong"'
Autor:
Qiu-Shi Zhuang, Xin-Bao Sun, Qing-Yun Chong, Arindam Banerjee, Min Zhang, Zheng-Sheng Wu, Tao Zhu, Vijay Pandey, Peter E. Lobie
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ARTEMIN (ARTN), one of the glial-cell derived neurotrophic factor family of ligands, has been reported to be associated with a number of human malignancies. In this study, the enhanced expression of ARTN in colorectal carcinoma (CRC) was observed; th
Externí odkaz:
https://doaj.org/article/9757c140e7734ec7af5c738df585e09b
Autor:
Tao Zhu, Peter E. Lobie, Keshuo Ding, Gaopeng Li, Sheng Tan, Xiangjun Kong, Pengxu Qian, Yanghao Zhong, Lan Hu, Xiao Zhang, Min Zhang, Qing-Yun Chong, Mingming Wu, Weijie Zhang
The dysregulation of miRNAs has been increasingly recognized as a critical mediator of cancer development and progression. Here, we show that frequent deletion of the MIR135A1 locus is associated with poor prognosis in primary breast cancer. Forced e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b27f711f32ce2fc9ad65cbae3c3d893
https://doi.org/10.1158/0008-5472.c.6512110.v1
https://doi.org/10.1158/0008-5472.c.6512110.v1
Autor:
Tao Zhu, Peter E. Lobie, Keshuo Ding, Gaopeng Li, Sheng Tan, Xiangjun Kong, Pengxu Qian, Yanghao Zhong, Lan Hu, Xiao Zhang, Min Zhang, Qing-Yun Chong, Mingming Wu, Weijie Zhang
Supplementary table S1 lists all the sequence of miR-135a mimic, siRNAs, shRNAs, and primers for plasmid construction, ChIP assay, and qRT-PCR used in this study. Supplementary table S2 shows the information of antibodies used in this study. Suppleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169f94ae81078b075ee04847ab501ca1
https://doi.org/10.1158/0008-5472.22425688.v1
https://doi.org/10.1158/0008-5472.22425688.v1
Autor:
Mengyi Zhang, Qing-Yun Chong, Alan Prem Kumar, Lingzhi Wang, Peter E. Lobie, Boon Cher Goh, Tao Zhu, Lan Ma, Zhinan Yin, Ru-Mei Chen, Zhengsheng Wu, Baocheng Wang, Yanxin Wang, Zhirong Guo, Basappa, Vijay Pandey
Publikováno v:
Oncogenesis, Vol 8, Iss 11, Pp 1-16 (2019)
Oncogenesis
Oncogenesis
TFF3 has been identified as a novel biomarker to distinguish between lung adenocarcinoma (ADC) and lung squamous-cell carcinoma (SCC). Herein, we determined the oncogenic functions of TFF3 and demonstrated the potential of pharmacological inhibition
Autor:
Zhengsheng Wu, Weijie Zhang, Hong Yan, Peter E. Lobie, Wenchang Qian, Sheng Tan, Yong Zhu, Tao Zhu, Qing-Yun Chong, Leiyan Yang
Publikováno v:
Cancer Management and Research. 11:5983-6001
Purpose: Evidence indicates that long noncoding RNAs (lncRNA) possess important roles in various cellular processes and that dysregulation of lncRNAs promotes tumor progression. However, the expression patterns and biological functions of many specif
Autor:
HM Poh, Vijay Pandey, Soo-Chin Lee, B. Salundi, Alan Prem Kumar, Ru-Mei Chen, Qing-Yun Chong, Peter E. Lobie
Publikováno v:
Cancer Research. 79:P6-20
Background Dose-dependent toxicity and acquired chemo-resistance are two major challenges in the use of doxorubicin in breast cancer treatment. Trefoil factor 3 (TFF3) is a secreted ligand that promotes breast cancer progression and predicts poor sur
Autor:
Min Zhang, Peter E. Lobie, Vijay Pandey, Ru-Mei Chen, Alan Prem Kumar, HM Poh, Qing-Yun Chong
Publikováno v:
Cancer Research. 79:P2-06
Background Oncogenic transformation is a complex multistep process where normal cells acquire the hallmarks of cancer, leading to unrestrained outgrowth of malignant clones. Trefoil Factor 3 (TFF3) is a clinically validated and functionally potent on
Autor:
Fenggang Yu, Nicholas L. Syn, Yanan Lu, Qing Yun Chong, Junyun Lai, Wei Jian Tan, Boon Cher Goh, Paul A. MacAry, Lingzhi Wang, Kwok Seng Loh
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Epstein-Barr virus (EBV) – the prototypical human tumor virus – is responsible for 1-2% of the global cancer burden, but divergent strains seem to exist in different geographical regions with distinct predilections for causing lymphoid or epithel
Autor:
Lan Ma, Ruby Yun-Ju Huang, Peter E. Lobie, Vijay Pandey, Alan Prem Kumar, Kanchuragoppal S Rangappa, Qing-Yun Chong, Tao Zhu, Yanxin Wang, Mengyi Zhang, Basappa, Yi-Shiou Chiou
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Platinum-based chemotherapy has been the standard treatment for ovarian cancer patients for approximately four decades. However, the prognosis of patients with advanced ovarian carcinoma remains dismal, mainly attributed to both dos
Autor:
Pengxu Qian, Mingming Wu, Weijie Zhang, Tao Zhu, Keshuo Ding, Yanghao Zhong, Gaopeng Li, Sheng Tan, Xiangjun Kong, Qing-Yun Chong, Peter E. Lobie, Xiao Zhang, Min Zhang, Lan Hu
Publikováno v:
Cancer Research. 78:4915-4928
The dysregulation of miRNAs has been increasingly recognized as a critical mediator of cancer development and progression. Here, we show that frequent deletion of the MIR135A1 locus is associated with poor prognosis in primary breast cancer. Forced e