Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Qing-Yin Zheng"'
Autor:
Xingtao Wang, Zhiyuan Ma, Zhongxiao Fu, Su Gao, Liu Yang, Yan Jin, Hui Sun, Chaoyun Wang, Weiming Fan, Lin Chen, Qing-Yin Zheng, Guoqiang Bi, Chun-Lei Ma
Publikováno v:
ASN Neuro, Vol 8 (2016)
Excessive glutamate release causes overactivation of N-methyl d -aspartate receptors (NMDARs), leading to excitatory neuronal damage in cerebral ischemia. Hydroxysafflor yellow A (HSYA), a compound extracted from Carthamus tinctorius L., has been rep
Externí odkaz:
https://doaj.org/article/7c50c183fb5b4bd89d7c354b89001260
Autor:
Tong Zhao, Tihua Zheng, Huining Yu, Bo Hua Hu, Bing Hu, Peng Ma, Ying Yang, Naidi Yang, Juan Hu, Tongtao Cao, Gang Chen, Bin Yan, Melina Peshoff, Maria Hatzoglou, Ruishuang Geng, Bo Li, Qing Yin Zheng
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-19 (2021)
Abstract Macroautophagy/autophagy is a highly conserved self-digestion pathway that plays an important role in cytoprotection under stress conditions. Autophagy is involved in hepatotoxicity induced by acetaminophen (APAP) in experimental animals and
Externí odkaz:
https://doaj.org/article/5b34cabca9e94098951e16b9308b23ba
Autor:
Yuerong Gong, Zhang Liu, Xiaolin Zhang, Shuang Shen, Qijun Xu, Hongchun Zhao, Jing Shang, Weiguo Li, Yanfei Wang, Jun Chen, Xiuzhen Liu, Qing Yin Zheng
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Norrie disease (ND; OMIM 310600), a rare X-linked recessive genetic disorder, is characterized by congenital blindness and occasionally, sensorineural hearing loss, and developmental delay. The congenital blindness of ND patients is almost untreatabl
Externí odkaz:
https://doaj.org/article/5e931b8a3dad4ad694f0a3da4ceaaf0b
Autor:
Daoli Xie, Tong Zhao, Xiaolin Zhang, Lihong Kui, Qin Wang, Yuancheng Wu, Tihua Zheng, Peng Ma, Yan Zhang, Helen Molteni, Ruishuang Geng, Ying Yang, Bo Li, Qing Yin Zheng
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
Otitis media (OM) is a pervasive disease that involves hearing loss and severe complications. In our previous study, we successfully established a mouse model of human OM using Tlr2tm1Kir (TLR2–/–) mice with middle ear (ME) inoculation of strepto
Externí odkaz:
https://doaj.org/article/5f7c6331c5534427806a573677dac627
Autor:
Tingzhi Deng, Jingjing Li, Jian Liu, Fuyi Xu, Xiaoya Liu, Jia Mi, Jonas Bergquist, Helen Wang, Chunhua Yang, Lu Lu, Xicheng Song, Cuifang Yao, Geng Tian, Qing Yin Zheng
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Age-related hearing loss (ARHL) is associated with cognitive dysfunction; however, the detailed underlying mechanisms remain unclear. The aim of this study is to investigate the potential underlying mechanism with a system genetics approach. A transc
Externí odkaz:
https://doaj.org/article/985930250b8d416bb364fea12288c929
Autor:
Qing Yin Zheng, Lihong Kui, Fuyi Xu, Tihua Zheng, Bo Li, Melinda McCarty, Zehua Sun, Aizheng Zhang, Luying Liu, Athena Starlard-Davenport, Ruben Stepanyan, Bo Hua Hu, Lu Lu
Publikováno v:
Neural Plasticity, Vol 2020 (2020)
Inbred mouse models are widely used to study age-related hearing loss (AHL). Many genes associated with AHL have been mapped in a variety of strains. However, little is known about gene variants that have the converse function—protective genes that
Externí odkaz:
https://doaj.org/article/b5a1f626f4c64d5ca37de4dcbcd4d318
Autor:
Lihong Kui, Ruben Stepanyan, Bo Li, Qing Yin Zheng, Athena Starlard-Davenport, Melinda S McCarty, Tihua Zheng, Luying Liu, Zehua Sun, Lu Lu, Bo Hua Hu, Aizheng Zhang, Fuyi Xu
Publikováno v:
Neural Plasticity, Vol 2020 (2020)
Neural Plasticity
Neural Plasticity
Inbred mouse models are widely used to study age-related hearing loss (AHL). Many genes associated with AHL have been mapped in a variety of strains. However, little is known about gene variants that have the converse function—protective genes that
Autor:
Bin Yan, Qing Yin Zheng, Tong Zhao, Ruishuang Geng, Bing Hu, Bo Li, Bo Hua Hu, Peng Ma, Qiang Zhang, Juan Hu, Tengyang Sun, Tihua Zheng, Ying Yang, Fangfang Zhao, Jing Yuan
Publikováno v:
Journal of neuroscience researchREFERENCES. 99(10)
Different mutations in the cadherin 23 (CDH23) gene in different genetic backgrounds have been linked to either syndromic or nonsyndromic forms of deafness in humans. We previously reported a progressive hearing loss (HL) mouse model, the Cdh23erl/er
Autor:
Tihua Zheng, Wenyi Huang, Heping Yu, Bo Hua Hu, Peter Song, Christopher M. McCarty, Lu Lu, Joseph Jaster, Ge Jin, Yan Zhang, Qing Yin Zheng
Publikováno v:
J Assoc Res Otolaryngol
Otitis media (OM) disease is a common cause of hearing loss that is primarily the result of middle ear infection. At present, our understanding of the mechanisms leading to OM is limited due to the lack of animal models of OM with effusion (OME). Her