Does PD-1 blockade play a decisive role in the pathological complete remission of unresectable MSS, BRAF V600E-mutated metastatic colorectal cancer: A case report

Autor: Li Tan, Qing-Shu Li, Dong Peng, Yong Cheng

Publikováno v: Frontiers in Oncology, Vol 12 (2023)

BackgroundColorectal cancer (CRC) ranks third in highest incidence among human cancers. With the continuous development of anti-cancer drugs, CRC patients are treated more and more effectively. However, the treatment of patients with unresectable met

Externí odkaz: https://doaj.org/article/57eeaa37a73c4f47bb32b90ec07022bf

Preliminary Study on the Identification of BRAFV600E Mutation in Colorectal Cancer by Near-Infrared Spectroscopy

Autor: Jiale Duan, Qing-Shu Li, Shuxian Zhang, Fan Qi, Lian Yang, Ya-Lan Wang, Ming Li, Lei Yin, Ming Xiao, Zhang Xue, Xian Li, Yi Tang, Yanping Yang, Hanjuan Gong

Publikováno v: OncoTargets and therapy
OncoTargets and Therapy, Vol Volume 13, Pp 13077-13085 (2020)

Jiale Duan,1,* Yanping Yang,1,* Lei Yin,1 Xue Zhang,2 Yi Tang,1 Shuxian Zhang,1 Hanjuan Gong,1 Ming Xiao,1 Ming Li,1 Qingshu Li,1 Xian Li,1 Lian Yang,1 Qi Fan,2 Yalan Wang1 1Department of Pathology, Molecular Medicine and Cancer Research Center, Chon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837a06c76f224d91a958bf450169b64f
http://europepmc.org/articles/PMC7764696

Down-Regulation of Laminin (LN)- α5 is Associated with Preeclampsia and Impairs Trophoblast Cell Viability and Invasiveness Through PI3K Signaling Pathway

Autor: Qin Li, Xue Mei Zhang, Phillip Baker, Hai Ying Li, Shuai Huang, Chao Tong, Qing Shu Li, Hong Bo Qi, Nan Shan, Ya Ming Liu, Xi Xiong

Publikováno v: Cellular Physiology and Biochemistry, Vol 51, Iss 5, Pp 2030-2040 (2018)

Background/Aims: Preeclampsia (PE) is a gestational disorder defined as hypertension and proteinuria, which is deemed a major cause of maternal and neonatal mortality and morbidity worldwide. The aim of this study was to investigate the expression pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c731a0e93cc1adc4a12576331fffe5b
https://www.karger.com/Article/FullText/495822

Identification of the role of mono-ADP-ribosylation in colorectal cancer by integrated transcriptome analysis

Autor: Qing-Shu Li, Hanjuan Gong, Shuxian Zhang, Yi Tang, Ya-Lan Wang, Ming Li, Yanping Yang, Jiale Duan, Ming Xiao

Publikováno v: Medical oncology (Northwood, London, England). 38(9)

Our previous study clarified the carcinogenic properties of arginine-specific mono-ADP-ribosyltransferase 1 (ART1), which results in a critical post-translational modification that changes the structure and function of proteins and is widely involved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d483b931ac2a0173638a536dfabc0e1
https://pubmed.ncbi.nlm.nih.gov/34357465

Mono-ADP-ribosylation of histone 3 at arginine-117 promotes proliferation through its interaction with P300

Autor: Xiao Lin, Michael D. Threadgill, Wen-Wen Chen, Feng Ling, Cong-Cong Jin, Cheng-Fang Wu, Qing-Shu Li, Lian Yang, Ya-Lan Wang, Ming Li, Wei Zhao, Zhen Zeng, Chang Liu, Xian Li, Yi Tang

Publikováno v: Oncotarget
Ling, F, Tang, Y, Li, M, Li, Q-S, Li, X, Yang, L, Zhao, W, Jin, C-C, Zeng, Z, Liu, C, Wu, C-F, Chen, W-W, Lin, X, Wang, Y-L & Threadgill, M 2017, ' Mono-ADP-ribosylation of histone 3 at arginine-117 promotes proliferation through its interaction with P300 ', Oncotarget, vol. 8, no. 42, pp. 72773-72787 . https://doi.org/10.18632/oncotarget.20347

Relatively little attention has been paid to ADP-ribosylated modifications of histones, especially to mono-ADP-ribosylation. As an increasing number of mono-ADP-ribosyltransferases have been identified in recent studies, the functions of mono-ADP-rib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2746d9e8d6f01ba37609b3351aad262
http://europepmc.org/articles/PMC5641168