Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Qing-Rong Liu"'
Autor:
Kanikkai Raja Aseer, Caio Henrique Mazucanti, Jennifer F. O’Connell, Isabel González-Mariscal, Anjali Verma, Qin Yao, Christopher Dunn, Qing-Rong Liu, Josephine M. Egan, Máire E. Doyle
Publikováno v:
Molecular Metabolism, Vol 82, Iss , Pp 101917- (2024)
Externí odkaz:
https://doaj.org/article/fc2998fbbee947e0b1e63770929e59bb
Autor:
Kanikkai Raja Aseer, Caio Henrique Mazucanti, Jennifer F. O’Connell, Isabel González-Mariscal, Anjali Verma, Qin Yao, Christopher Dunn, Qing-Rong Liu, Josephine M. Egan, Máire E. Doyle
Publikováno v:
Molecular Metabolism, Vol 82, Iss , Pp 101906- (2024)
Objective: Type 1 diabetes (T1D) occurs because of islet infiltration by autoreactive immune cells leading to destruction of beta cells and it is becoming evident that beta cell dysfunction partakes in this process. We previously reported that geneti
Externí odkaz:
https://doaj.org/article/f9b137e5ebbd4b2fba8b127ac6e303d3
Autor:
Aaliyah Roberts, Mahli Christian, Lizbeth Nivar Dilone, Natania Nelson, Mark Joseph Endrino, Adam Kneebone, Shymaa Embaby, Justin Fernandez, Qing-Rong Liu, Emmanuel S. Onaivi, Berhanu Geresu Kibret
Publikováno v:
Advances in Drug and Alcohol Research, Vol 3 (2023)
The endocannabinoidome (eCBome) is the expanded endocannabinoid system (ECS) and studies show that there is a link between this system and how it modulates alcohol induced neuroinflammation. Using conditional knockout (cKO) mice with selective deleti
Externí odkaz:
https://doaj.org/article/d21f491302164d2898e21009bb0c9263
Autor:
Caio Henrique Mazucanti, Vernon Kennedy, Jr., Hasitha U. Premathilake, Maire E. Doyle, Jane Tian, Qing-Rong Liu, Jennifer O’Connell, Simonetta Camandola, Josephine M. Egan
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112903- (2023)
Summary: The choroid plexus (CP) is a source of trophic factors for the developing and mature brain. Insulin is produced in epithelial cells of the CP (EChPs), and its secretion is stimulated by Htr2c-mediated signaling. We modulated insulin expressi
Externí odkaz:
https://doaj.org/article/643acc5a5f964316adb37029ebb0c598
Autor:
Yoo Kim, Sudeep Gautam, Kanikkai Raja Aseer, Jaekwan Kim, Prabha Chandrasekaran, Caio Henrique Mazucanti, Paritosh Ghosh, Jennifer F. O’Connell, Máire E. Doyle, Ashley Appleton, Elin Lehrmann, Qing-Rong Liu, Josephine M. Egan
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-13 (2020)
Abstract Cannabinoid 1 receptor (CB1R) expression is upregulated in the liver with viral hepatitis, cirrhosis, and both alcoholic and non-alcoholic fatty liver disease (FLD), whereas its expression is muted under usual physiological conditions. Inhib
Externí odkaz:
https://doaj.org/article/9666fd9589f04fc68c08c674919873b5
Autor:
Ana Canseco-Alba, Branden Sanabria, Mariam Hammouda, Rollanda Bernadin, Marizel Mina, Qing-Rong Liu, Emmanuel S. Onaivi
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2022)
DAT-Cnr2 mice are conditional knockout (cKO) animals that do not express cannabinoid CB2 receptors (CB2R), in midbrain dopamine neurons. The hyperactivity phenotype of DAT-Cnr2 cKO mice were paradoxically reduced by low dose of amphetamine. Here, we
Externí odkaz:
https://doaj.org/article/7b95c229ddbd48e7a21382908c5e352b
Autor:
Qing-Rong Liu, Kanikkai Raja Aseer, Qin Yao, Xiaoming Zhong, Paritosh Ghosh, Jennifer F. O’Connell, Josephine M. Egan
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Type 1 diabetes mellitus (T1DM) is an autoimmune disease resulting from loss of insulin-secreting β-cells in islets of Langerhans. The loss of β-cells is initiated when self-tolerance to β-cell-derived contents breaks down, which leads to T cell-m
Externí odkaz:
https://doaj.org/article/72eb20ce937f45c88093881f016d9ad4
Autor:
Qing-Rong Liu, Min Zhu, Qinghua Chen, Maja Mustapic, Dimitrios Kapogiannis, Josephine M. Egan
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 167 (2023)
(1) Background and aims: Amyloidosis due to aggregation of amyloid-β (Aβ42) is a key pathogenic event in Alzheimer’s disease (AD), whereas aggregation of mature islet amyloid polypeptide (IAPP37) in human islets leads to β-cell dysfunction. The
Externí odkaz:
https://doaj.org/article/5d286cbf17304f938149ba2559e0f91e
Autor:
Akitoyo Hishimoto, Olga Pletnikova, Doyle Lu Lang, Juan C. Troncoso, Josephine M. Egan, Qing-Rong Liu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2019)
Abstract Background Synaptic damage precedes neuron death in Alzheimer’s disease (AD). Neurexins, NRXN1, NRXN2, and NRXN3, are presynaptic adhesion molecules that specify neuron synapses and regulate neurotransmitter release. Neurexins and postsyna
Externí odkaz:
https://doaj.org/article/16931f3259ce4793b2004b5c49e0ab0e
Autor:
Da-Chang Bai, Fei-Le Yu, Wan-Ying Wang, Di Chen, Hao Li, Qing-Rong Liu, Chang-Hua Ding, Bo Chen, Xue-Long Hou
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Palladium catalyzed allylic substitution reactions typically proceed via an outer sphere mechanism, yielding predominately linear products. Here, the authors report an inner sphere process for the allylic substitution of ketone enolates, giving branc
Externí odkaz:
https://doaj.org/article/a2190ea2df8449c6b683e64e74797d1d