Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Qing-Ri Cao"'
Autor:
Ju-Hyeong Woo, Hai V. Ngo, Hy D. Nguyen, Myung-Chul Gil, Chulhun Park, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e23091- (2023)
The aim of this study was to design a novel matrix tablet with enhanced dissolution and pH-independent controlled release of sildenafil citrate (SIL), a drug with pH-dependent solubility, by using solid dispersions (SDs) and polyelectrostatic interac
Externí odkaz:
https://doaj.org/article/6dfbc9ecc056445a8391d43e5a9155b3
Autor:
Chulhun Park, Nileshkumar M. Meghani, Yongkwan Shin, Euichaul Oh, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Thao Truong-Dinh Tran, Phuong Ha-Lien Tran, Beom-Jin Lee
Publikováno v:
Pharmaceutics, Vol 11, Iss 3, p 102 (2019)
The crystal changes and salt formation of poorly water-soluble telmisartan (TEL) in various solvents were investigated for enhanced solubility, stability and crystallinity. Polymorphic behaviors of TEL were characterized by dispersing in distilled wa
Externí odkaz:
https://doaj.org/article/f3629e4395c141e28b3221bbbc1040c6
Publikováno v:
Current Drug Delivery. 19:721-729
Purpose: Traditional dosage forms of granisetron (GRN) decrease patient compliance associated with repeated drug administration because of the short half-life of the drug. Methods: In this study, novel GRN-loaded Polylactic-co-glycolic Acid (PLGA) su
Autor:
Yi Zhang, Jing-Hao Cui, Wei Sun, Atef Mohammed Qasem Ahmed, Hao-Yan Huang, Huan-Huan Du, Shunli Dong, Dingyun Cao, Qing-Ri Cao, Li-Qing Chen
Publikováno v:
Theranostics
Purpose: Novel collagenase IV (ColIV) and clusterin (CLU)-modified polycaprolactone-polyethylene glycol (PCL-PEG) nanoparticles that load doxorubicin (DOX) were designed and fully evaluated in vitro and in vivo. Methods: PCL-PEG-ColIV was synthesized
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 152:257-269
This study aimed to design the ideal nanonizing vehicle for poorly water-soluble model curcumin (CCM) using fattigation-platform nanotechnology, and to investigate the effects of fatty acid salts chain length on nanonizing CCM and its efficient deliv
Publikováno v:
International journal of pharmaceutics. 619
In this study, the electrostatic molecular effect of differently charged surfactants on the solubilization capacity and physicochemical properties of salt-caged nanosuspensions (NSPs) containing poorly water-soluble drug was investigated. Anionic reb
Autor:
Qing-Ri Cao, Jing Tao, Yue Cao, Atef Mohammed Qasem Ahmed, Huan-Huan Du, Wei Sun, Xiaojuan Lu, Zhao Xu
Publikováno v:
Current drug delivery. 19(9)
Objective: This study aimed to prepare combretastatin A4 (CA4)-loaded nanoparticles (CA4 NPs) using poly(lactic-co-glycolic acid) (PLGA) and soybean lecithin (Lipoid S100) as carriers, and further evaluate the physicochemical properties and cytotoxic
Autor:
Huan-Huan Du, Leshuai W Zhang, Qing-Ri Cao, Jing-Hao Cui, Hao-Yan Huang, Beom-Jin Lee, Yue Cao, Li-Qing Chen
Publikováno v:
ACS Applied Materials & Interfaces. 11:9763-9776
The combination of gene therapy and chemotherapy has recently received considerable attention for cancer treatment. However, low transfection efficiency and poor endosomal escape of genes from nanocarriers strongly limit the success of the clinical u
Autor:
Qing-Ri Cao, Pu-Song Zhao, Yi Wang, Hao-Yuan Yu, Li-Fan Hu, Lei Xing, Hu-Lin Jiang, Lian-Yu Qi, Xiang-Dong Gao
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 341
The essential challenge of gene therapy is to develop safe and efficient vectors that escort genes to target sites. However, due to the cumbersome workflow of gene transfection into cells, successive gene loss occurs. This leads to considerable reduc
Autor:
Gang, Jin, Hai V, Ngo, Jie, Wang, Jing-Hao, Cui, Qing-Ri, Cao, Chulhun, Park, Minji, Jung, Beom-Jin, Lee
Publikováno v:
International Journal of Pharmaceutics. 619:121718
The purpose of this study was to develop a once-daily, bilayer matrix tablet with immediate (IR) and sustained release (SR) layers of poorly water-soluble and absorption site dependent rebamipide (RBM) to substitute three times a day IR tablet. Owing