Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Qing-Guo Ruan"'
Publikováno v:
Guoji Yanke Zazhi, Vol 19, Iss 1, Pp 51-55 (2019)
Keratoplasty is routinely used to treat end-stage corneal diseases. However, immune-mediated graft rejection remains the major cause of surgical failure. Organ transplant rejection is often due to the directional migration and homing of inflammatory
Externí odkaz:
https://doaj.org/article/c8498704cea74969ae6e14de3866d23d
Autor:
Leena Peltonen, Yan Zhang, Bing Yi, Weipeng Zheng, Qing-Guo Ruan, Jin-Xiong She, Sharad Purohit, Sarah Eckenrode, Daniel Eisenman, Kenneth S. K. Tung, Yulius Setiady
Publikováno v:
The Journal of Immunology. 178:7173-7180
The autoimmune regulator (Aire) gene plays an essential role in negative selection of T cells and deletion of autoreactive T cells in the thymus. The defect in thymic selection in Aire−/− mice was attributed to the repressed expression of tissue-
Autor:
Qing Guo Ruan, Jin-Xiong She
Publikováno v:
Clinics in Laboratory Medicine. 24:305-317
The autoimmune polyglandular syndrome type I (APSI) is an auto-somal recessive disorder that is characterized by chronic mucocutaneous candidiasis, multiple autoimmune endocrinopathies, and ectodermal dystrophies. The gene that is responsible for APS
Publikováno v:
Diabetes. 53:366-375
cDNA microarrays with >11,000 cDNA clones from an NOD spleen cDNA library were used to identify temporal gene expression changes in NOD mice (1–10 weeks), which spontaneously develop type 1 diabetes, and changes between NOD and NOD congenic mice (N
Autor:
Kim Ahrens, Li-Jun Yang, Hongshan Zhao, Qing Guo Ruan, Sarah Eckenrode, Christine Collins, Jin-Xiong She, Richard A. McIndoe, Shiwu Li
Publikováno v:
The Journal of Molecular Diagnostics. 5:212-221
Using cDNA microarrays we determined the gene expression patterns in the human acute promyelocytic leukemia (APL) cell line NB4 during all-trans retinoic acid (ATRA)-induced differentiation. We analyzed the expression of 12,288 genes in the NB4 cells
Autor:
Ping Yang, Sarah Eckenrode, Karen H.S. Wilson, Richard A. McIndoe, Jin-Xiong She, Qing Guo Ruan, Abdoreza Davoodi-Semiromi, Quan Zhen Li, Byron P. Croker, Jing Da Shi
Publikováno v:
Diabetes. 52:2151-2159
We profiled the expression of 5,760 clones from a kidney subtraction library in the kidneys of three groups of NOD mice: nondiabetic, new-onset, and long-term diabetic. A total of 27 genes had lower expression and 1 gene (Gpx3) had higher expression
Autor:
Quan-Zhen Li, Sarah Eckenrode, Qing-Guo Ruan, Cong-Yi Wang, Jing-Da Shi, Richard A. McIndoe, Jin-Xiong She
Publikováno v:
Mammalian Genome. :0830-0836
Autor:
James J. Yang, Sarah Eckenrode, Richard A. McIndoe, Samuel S. Wu, Jin-Xiong She, Mark C. K. Yang, Qing-Guo Ruan
Publikováno v:
Physiological Genomics. 7:45-53
Over the last few years, there has been a dramatic increase in the use of cDNA microarrays to monitor gene expression changes in biological systems. Data from these experiments are usually transformed into expression ratios between experimental sampl
Autor:
Quan Zhen Li, Cong-Yi Wang, Wei Lian, Donghai Wu, Qing Guo Ruan, Sarah Eckenrode, Jin Da Shi, Thomas Kukar, Yunrong Gu, Jin-Xiong She, Abdoreza Davoodi-Semiromi
Publikováno v:
Gene. 273:275-284
We report here the cloning and characterization of a novel gene belonging to the tubby superfamily proteins (TUSP) in mouse and human. The mouse Tusp cDNA is 9120 bp in length and encodes a deduced protein of 1547 amino acids, while the human TUSP ge
Autor:
Bobbilynn Hawkins-Lee, Michele P. Marron, Yi-Qun Huang, Qing-Guo Ruan, Jing-Da Shi, Cong-Yi Wang, Jin-Xiong She, Bernardo Ochoa
Publikováno v:
American Journal of Medical Genetics. 84:454-459
The urofacial (Ochoa) syndrome (UFS) is a rare autosomal recessive disorder characterized by abnormal facial expression and urinary abnormalities. Previously, we mapped the gene to a genomic interval of approximately 1 cM on chromosome region 10q23-2