Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Qing-Fen Gan"'
Autor:
Kooiker, Kristina1,2,3,4 kkooiker@uw.edu, Qing-Fen Gan5, Ming Yu5, Na Sa5, Mohran, Saffie1,2,3,4, Yuanhua Cheng6, Flint, Galina2,4,6, Neys, Stephanie1,2,3,4, Chengqian Gao7, Nissen, Devin8, McMillen, Tim2,4,9, Asencio, Anthony2,4,6, Weikang Ma8, Irving, Thomas C.8, Moussavi-Harami, Farid1,2,3,4,10, Regnier, Michael2,3,4,6
Publikováno v:
Journal of General Physiology. Oct2024, Vol. 156 Issue 10, p1-S6. 19p.
Publikováno v:
The Journal of Biological Chemistry
A hallmark feature of myosin-II is that it can spontaneously self-assemble into bipolar synthetic thick filaments (STFs) in low ionic strength buffers, thereby serving as a reconstituted in-vitro model for muscle thick filament. While these STFs have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0bfbff28fa0b211d2a00a4347e7626
http://europepmc.org/articles/PMC7948491
http://europepmc.org/articles/PMC7948491
Autor:
Ofra Yanuka, Markus Boehringer, Alicia Leikin-Frenkel, Uri Ben-David, Martin Graf, Yifat S. Oren, Payal Arora, Ralph Garippa, Qing-Fen Gan, Tamar Golan-Lev, Gianni Gromo, Nissim Benvenisty
Publikováno v:
Cell Stem Cell. 12(2):167-179
SummaryThe use of human pluripotent stem cells (hPSCs) in cell therapy is hindered by the tumorigenic risk from residual undifferentiated cells. Here we performed a high-throughput screen of over 52,000 small molecules and identified 15 pluripotent c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686394d68fd2ff6a1e658db77f1924eb
Autor:
Shirley Li, Kelly M. George, Shelley K. Gleason, Charles Wartchow, Binh Thanh Vu, Hong Qian, Ann C. Petersen, Qing-Fen Gan, Lin Gao, Gabriel Stephen Deems, Linghao Niu, Nanda Beatini, Johannes C. Hermann, Arjun Narayanan, John Menke, Nathan Robert Scott, Nancy-Ellen Haynes, Yingsi Chen
Publikováno v:
ACS Medicinal Chemistry Letters. 4:197-200
Organic impurities in compound libraries are known to often cause false-positive signals in screening campaigns for new leads, but organic impurities do not fully account for all false-positive results. We discovered inorganic impurities in our scree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ba9438c9107f86a17a7e7700489491
https://doi.org/10.1021/ml3003296
https://doi.org/10.1021/ml3003296
Publikováno v:
Journal of Biological Chemistry. 271:25412-25418
Mammalian lipoxygenases have been implicated in the pathogenesis of several inflammatory disorders and are, therefore, important targets for drug discovery. Both plant and mammalian lipoxygenases catalyze the dioxygenation of polyunsaturated fatty ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef55c882323ec9eec26ac4707178c825
https://doi.org/10.1074/jbc.271.41.25412
https://doi.org/10.1074/jbc.271.41.25412
Publikováno v:
Journal of the American Chemical Society. 117:7422-7427
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d41c5aa5b3c5e483381a85a6b293cfa
https://doi.org/10.1021/ja00133a015
https://doi.org/10.1021/ja00133a015
Autor:
Pamela Volkel, Yi-Zheng Xu, Martin Huber, Teresa Biegel, Chakkodabylu S. Ramesha, Simon W. Lee, Marie Dinh, Liliana E. Scarafia, Jim W. Barnett, Qing-Fen Gan, Amy Y. Mak, Stacie A. Dalrymple, On-Yee So, James Patrick Dunn, Mary Mulkins, David C. Swinney, Ina Lee
Publikováno v:
The Journal of biological chemistry. 277(26)
A small molecule inhibitor of NF-kappaB-dependent cytokine expression was discovered that blocked tumor necrosis factor (TNF) alpha-induced IkappaB(alpha) degradation in MM6 cells but not the degradation of beta-catenin in Jurkat cells. Ro106-9920 bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa26b171203043d8e1aa00e897eed2ae
https://pubmed.ncbi.nlm.nih.gov/11950839
https://pubmed.ncbi.nlm.nih.gov/11950839
Publikováno v:
Inorganic Chemistry. 29:2549-2551
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eba521e7949a0136a5ed58ca7ca36ab3
https://doi.org/10.1021/ic00339a001
https://doi.org/10.1021/ic00339a001
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781489918123
Mammalian lipoxygenases have been implicated in the pathogenesis of various inflammatory conditions such as arthritis, psoriasis and bronchial asthma.1, 2 There is also evidence that 15-lipoxygenase may play a role in the progression of atheroscleros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cface80a0891ef00bccb6a5fc50415c5
https://doi.org/10.1007/978-1-4899-1810-9_96
https://doi.org/10.1007/978-1-4899-1810-9_96
Publikováno v:
Biochemistry. 34(21)
Mammalian 15-lipoxygenases undergo a characteristic self-inactivation. The oxygenation of a single methionine to methionine sulfoxide, by 13(S)-hydroperoxyoctadecadienoic acid (13-HPODE), was previously suggested as the cause of the inactivation of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b035b80c4698c4fcb5f459e34195138
https://pubmed.ncbi.nlm.nih.gov/7766617
https://pubmed.ncbi.nlm.nih.gov/7766617