Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Qing Yu Weng"'
Autor:
Nisma Mujahid, Yanke Liang, Ryo Murakami, Hwan Geun Choi, Allison S. Dobry, Jinhua Wang, Yusuke Suita, Qing Yu Weng, Jennifer Allouche, Lajos V. Kemeny, Andrea L. Hermann, Elisabeth M. Roider, Nathanael S. Gray, David E. Fisher
Publikováno v:
Cell Reports, Vol 19, Iss 11, Pp 2177-2184 (2017)
The presence of dark melanin (eumelanin) within human epidermis represents one of the strongest predictors of low skin cancer risk. Topical rescue of eumelanin synthesis, previously achieved in “redhaired” Mc1r-deficient mice, demonstrated signif
Externí odkaz:
https://doaj.org/article/34194a1909244e6f82c306ad7f40aebb
Autor:
David E. Fisher, Bradley E. Bernstein, Leonard I. Zon, Julia Newton-Bishop, Jian Jin, Yan Xiong, Brian B. Liau, C. Thomas Powell, Whitney Silkworth, Yang Feng, Yao Zhan, Lajos V. Kemeny, Ellen van Rooijen, Jennifer A. Lo, Nhu Nguyen, Yotam Drier, Joey Mark S. Diaz, Joanna Pozniak, Sathya Muralidhar, Kevin Y. Chen, Megan L. Insco, Qing Yu Weng, Shinichiro Kato
Primer sequences used in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f58fdc7412d1fab7f29f1b9ac4dfd0
https://doi.org/10.1158/2159-8290.22535410
https://doi.org/10.1158/2159-8290.22535410
Autor:
David E. Fisher, Bradley E. Bernstein, Leonard I. Zon, Julia Newton-Bishop, Jian Jin, Yan Xiong, Brian B. Liau, C. Thomas Powell, Whitney Silkworth, Yang Feng, Yao Zhan, Lajos V. Kemeny, Ellen van Rooijen, Jennifer A. Lo, Nhu Nguyen, Yotam Drier, Joey Mark S. Diaz, Joanna Pozniak, Sathya Muralidhar, Kevin Y. Chen, Megan L. Insco, Qing Yu Weng, Shinichiro Kato
Epigenetic regulators, when genomically altered, may become driver oncogenes that mediate otherwise unexplained pro-oncogenic changes lacking a clear genetic stimulus, such as activation of the WNT/β-catenin pathway in melanoma. This study identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36a348e4563481b651158ecb74bd36dd
https://doi.org/10.1158/2159-8290.c.6547855.v1
https://doi.org/10.1158/2159-8290.c.6547855.v1
Autor:
Dieter Manstein, Martin W. LaFleur, Arlene H. Sharpe, Marcelo Pereira da Silva, Lajos Kemény, Mack Y. Su, Kristen E. Pauken, Masayoshi Kawakubo, David E. Fisher, S. Alireza Rabi, Tal Hadad Erlich, Catherine J. Wu, Rumya Raghavan, Genevieve M. Boland, Edward P. Browne, Mamunur Rashid, Yu Xu, Mai P. Hoang, Dennie T. Frederick, Jennifer A. Lo, Constance E. Brinckerhoff, Jennifer Allouche, David W. Mullins, David J. Adams, Anita A. J. van der Sande, Vikram R. Juneja, Mohsen Malehmir, Levi A. Garraway, David J. Lieb, Gordon J. Freeman, Keith T. Flaherty, Gyulnara G. Kasumova, Belinda Wang, Elisabeth Roider, Nir Hacohen, Whitney Silkworth, Qing Yu Weng
Publikováno v:
Sci Transl Med
Although immune checkpoint inhibitors (ICIs), such as anti-programmed cell death protein 1 (PD-1), can deliver durable anti-tumor effects, most patients with cancer fail to respond. Recent studies suggest that ICI efficacy correlates with a higher lo
Autor:
Henry W. Long, Kai W. Wucherpfennig, Rong En Tay, David E. Fisher, Hye-Jung Kim, Clifford A. Meyer, Qing Yu Weng, Paloma Cejas, Yoshinaga Ito, Yingtian Xie, Myles Brown, Olamide Olawoyin
Publikováno v:
The Journal of Experimental Medicine
Tay et al. show that HDAC3 acts early during CD8 T cell activation to inhibit cytotoxicity and effector differentiation gene programs. This study identifies a novel role for HDAC3 as an epigenetic regulator of CD8 T cell cytotoxicity and persistence
Autor:
Myles Brown, Olamide Olawoyin, Clifford A. Meyer, David E. Fisher, Qing Yu Weng, Kai W. Wucherpfennig, Yingtian Xie, Rong En Tay, Yoshinaga Ito, Henry W. Long, Hye-Jung Kim, Paloma Cejas
Publikováno v:
Journal of Experimental Medicine. 217
Cytotoxic T cells play a key role in adaptive immunity by killing infected or cancerous cells. While the transcriptional control of CD8 T cell differentiation and effector function following T cell activation has been extensively studied, little is k
Autor:
Joanna Pozniak, Lajos Kemény, Bradley E. Bernstein, Kevin Yining Chen, Yao Zhan, Yan Xiong, Yang Feng, Ellen van Rooijen, Yotam Drier, Megan L. Insco, Whitney Silkworth, Brian B. Liau, Julia Newton-Bishop, Joey Mark S. Diaz, Jennifer A. Lo, Sathya Muralidhar, Nhu T. Nguyen, David E. Fisher, Shinichiro Kato, Qing Yu Weng, Jian Jin, C. Thomas Powell, Leonard I. Zon
Publikováno v:
Cancer Discov
Epigenetic regulators, when genomically altered, may become driver oncogenes that mediate otherwise unexplained pro-oncogenic changes lacking a clear genetic stimulus, such as activation of the WNT/β-catenin pathway in melanoma. This study identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c385ab333279b0a0464c0c05c3b2e4
https://europepmc.org/articles/PMC7334057/
https://europepmc.org/articles/PMC7334057/
Autor:
Johanna S Song, Mackenzie Asel, Qing Yu Weng, Scott R. Granter, Lauren N. Ko, Arash Mostaghimi
Publikováno v:
Case Reports in Oncology, Vol 10, Iss 3, Pp 987-991 (2017)
Case Reports in Oncology
Case Reports in Oncology
NUT (nuclear protein of the testis) midline carcinoma (NMC) is a rare, poorly differentiated neoplasm with dismal prognosis. Though NMC are often metastatic by the time of presentation, cutaneous metastases have not been well described in the literat
Autor:
Jennifer J. Hsiao, Ju Hee Lee, Hequn Wang, Francisco Rothhammer, Conor L. Evans, Kazumasa Wakamatsu, Vivien Igras, David E. Fisher, Alicia M. McConnell, Jianming Zhang, Paula P. Navarro, Maria Vittoria Schiaffino, Luba M. Pardo, Gabriel Bedoya, Kathleen A. Christie, Antonio Cozzio, Tamar Nijsten, Thomas Ruzicka, Victor Acuna-Alonso, Giovanni Poletti, Luke H. Chao, Carla Gallo, Kaspar Itin, Othon Iliopoulos, Qing Yu Weng, Shosuke Ito, Alexander A. Navarini, Lajos Kemény, Kaustubh Adhikari, Akinori Kawakami, Yusuke Suita, Shaohua Fan, Haley R. Noonan, Nisma Mujahid, Camila Makhlouta Lugo, Elisabeth Roider, Inbal Rachmin, Samuel Canizales-Quinteros, Leonard I. Zon, Maria Cátira Bortolini, Alyssa Lovas, Chong Hyun Won, István Németh, Jennifer A. Lo, Nhu T. Nguyen, Benjamin P. Kleinstiver, Jennifer Allouche, Sarah A. Tishkoff, Carola Berking, Andres Ruiz-Linares, Rolando González-José, Sam Osseiran, Shinichiro Kato
Publikováno v:
Cell, 184(16), 4268-4283.e20. Cell Press
Ultraviolet (UV) light and incompletely understood genetic and epigenetic variations determine skin color. Here we describe an UV- and microphthalmia-associated transcription factor (MITF)-independent mechanism of skin pigmentation. Targeting the mit
Autor:
Andrea L. Hermann, Jennifer Allouche, Nisma Mujahid, Jinhua Wang, Qing Yu Weng, David E. Fisher, Yusuke Suita, Elisabeth Roider, Nathanael S. Gray, Yanke Liang, Allison S. Dobry, Ryo Murakami, Lajos Kemény, Hwan Geun Choi
Publikováno v:
Cell reports
Cell Reports, Vol 19, Iss 11, Pp 2177-2184 (2017)
Cell Reports, Vol 19, Iss 11, Pp 2177-2184 (2017)
SUMMARY The presence of dark melanin (eumelanin) within human epidermis represents one of the strongest predictors of low skin cancer risk. Topical rescue of eumelanin synthesis, previously achieved in “redhaired” Mc1r-deficient mice, demonstrate