Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Qing You Pang"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Epithelial-mesenchymal transition (EMT) is a dynamic process enabling polarized epithelial cells to acquire mesenchymal features implicated in development and carcinoma progression. As our understanding evolves, it is clear the reversible ex
Externí odkaz:
https://doaj.org/article/abbf2eacf6314d1dbfa0dd040f927430
Autor:
Yan Zhang, Chi Yan Wong, Carine Z. J. Lim, Qingchang Chen, Zhonglang Yu, Auginia Natalia, Zhigang Wang, Qing You Pang, See Wee Lim, Tze Ping Loh, Beng Ti Ang, Carol Tang, Huilin Shao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Current technologies to subtype glioblastoma (GBM), the most lethal brain tumor, require highly invasive brain biopsies. Here, we develop a dedicated analytical platform to achieve direct and multiplexed profiling of circulating RNAs in extr
Externí odkaz:
https://doaj.org/article/3a2f3d7de2f943d495f2efd2b80e76d0
Autor:
Qing You Pang, Tuan Zea Tan, Vignesh Sundararajan, Yi-Chia Chiu, Edward Yu Wing Chee, Vin Yee Chung, Mahesh A. Choolani, Ruby Yun-Ju Huang
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-31 (2022)
Abstract Background The plasticity along the epithelial-mesenchymal transition (EMT) spectrum has been shown to be regulated by various epigenetic repertoires. Emerging evidence of local chromatin conformation changes suggests that regulation of EMT
Externí odkaz:
https://doaj.org/article/724cb006a5314591b4fd1dcd91a52103
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Among the transcription factors that are conserved across phylogeny, the grainyhead family holds vital roles in driving the epithelial cell fate. In Drosophila, the function of grainyhead (grh) gene is essential during developmental processes such as
Externí odkaz:
https://doaj.org/article/6b0ddb87b59e4870990f2015f6e185f2
Autor:
Jolene Caifeng Ho, Lissa Nurrul Abdullah, Qing You Pang, Sudhakar Jha, Edward Kai-Hua Chow, Henry Yang, Hiroyuki Kato, Lorenz Poellinger, Jun Ueda, Kian Leong Lee
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188051 (2017)
Epigenetic mechanisms play important roles in the regulation of tumorigenesis, and hypoxia-induced epigenetic changes may be critical for the adaptation of cancer cells to the hypoxic microenvironment of solid tumors. Previously, we showed that loss-
Externí odkaz:
https://doaj.org/article/0b49f98fac7a42c19c316bb162a3080e
Autor:
Lynnette Koh, Wisna Novera, See Wee Lim, Yuk Kien Chong, Qing You Pang, David Low, Beng Ti Ang, Carol Tang
Publikováno v:
Pharmacological research. 182
This review describes recent technological advances applied to glioblastoma (GBM), a brain tumor with dismal prognosis. International consortial efforts suggest the presence of molecular subtypes within histologically identical GBM tumors. This empha
Autor:
Qing You Pang, Tuan Zea Tan, Vignesh Sundararajan, Yi-Chia Chiu, Edward Yu Wing Chee, Vin Yee Chung, Mahesh A. Choolani, Ruby Yun-Ju Huang
Publikováno v:
Genome biology. 23(1)
Background The plasticity along the epithelial-mesenchymal transition (EMT) spectrum has been shown to be regulated by various epigenetic repertoires. Emerging evidence of local chromatin conformation changes suggests that regulation of EMT may occur
Autor:
Ruby Yun-Ju Huang, Jieru Ye, Vin Yee Chung, Qing You Pang, Tuan Zea Tan, Ming Tan, Vignesh Sundararajan
Publikováno v:
Cancers, Vol 12, Iss 3777, p 3777 (2020)
The authors wish to make the following corrections to this paper [...]
Autor:
Tuan Zea Tan, Ruby Yun-Ju Huang, Vignesh Sundararajan, Vin Yee Chung, Qing You Pang, Jieru Ye, Ming Tan
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1140, p 1140 (2020)
Volume 12
Issue 5
Cancers, Vol 12, Iss 1140, p 1140 (2020)
Volume 12
Issue 5
Over two decades of research on cancer-associated epithelial-mesenchymal transition (EMT) led us to ascertain the occurrence of transitional intermediate states (collectively referred to as the EMT spectrum). Among the molecular factors that drive EM
Autor:
Henry Yang, Lorenz Poellinger, Sudhakar Jha, Lissa Nurrul Abdullah, Qing You Pang, Edward Kai-Hua Chow, Hiroyuki Kato, Jolene Caifeng Ho, Kian Leong Lee, Jun Ueda
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0188051 (2017)
PLoS ONE, Vol 12, Iss 11, p e0188051 (2017)
Epigenetic mechanisms play important roles in the regulation of tumorigenesis, and hypoxia-induced epigenetic changes may be critical for the adaptation of cancer cells to the hypoxic microenvironment of solid tumors. Previously, we showed that loss-