Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Qing Shuo Zhang"'
Autor:
Qing-Shuo Zhang, Matthew Deater, Kathryn Schubert, Laura Marquez-Loza, Carl Pelz, David A. Sinclair, Markus Grompe
Publikováno v:
Stem Cell Research, Vol 15, Iss 1, Pp 130-140 (2015)
Fanconi anemia is a genetic bone marrow failure syndrome. The current treatment options are suboptimal and do not prevent the eventual onset of aplastic anemia requiring bone marrow transplantation. We previously showed that resveratrol, an antioxida
Externí odkaz:
https://doaj.org/article/a809e38fe36d45ec870375f4407bda2d
Autor:
Qing-Shuo Zhang, Eric Benedetti, Matthew Deater, Kathryn Schubert, Angela Major, Carl Pelz, Soren Impey, Laura Marquez-Loza, R. Keaney Rathbun, Shigeaki Kato, Grover C. Bagby, Markus Grompe
Publikováno v:
Stem Cell Reports, Vol 4, Iss 1, Pp 90-102 (2015)
Summary: Androgens are widely used for treating Fanconi anemia (FA) and other human bone marrow failure syndromes, but their mode of action remains incompletely understood. Aged Fancd2−/− mice were used to assess the therapeutic efficacy of oxyme
Externí odkaz:
https://doaj.org/article/8a6306b4c4804260b2652a1314bac711
Autor:
Qing Shuo Zhang, Sean Nygaard, Niveditha Balaji, Kevin Baradar, Markus Grompe, Amita Tiyaboonchai, Angela Major
Publikováno v:
Hum Gene Ther
The efficiency of gene repair by homologous recombination in the liver is enhanced by CRISP/Cas9 incision near the mutation. In this study, we explored interventions designed to further enhance in vivo hepatocyte gene repair in a model of hereditary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5114a545e64dc10358cf8ec7066512f3
https://pubmed.ncbi.nlm.nih.gov/32729326
https://pubmed.ncbi.nlm.nih.gov/32729326
Autor:
Shaomei Wang, Bin Lu, Sergei Girman, Jie Duan, Trevor McFarland, Qing-shuo Zhang, Markus Grompe, Grazyna Adamus, Binoy Appukuttan, Raymond Lund
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9200 (2010)
BACKGROUND: Retinitis pigmentosa (RP) is characterized by progressive night blindness, visual field loss, altered vascular permeability and loss of central vision. Currently there is no effective treatment available except gene replacement therapy ha
Externí odkaz:
https://doaj.org/article/d539180245324ab18e253cd221a049a4
Autor:
Gengxin Chen, Wanhe Li, Qing-Shuo Zhang, Michael Regulski, Nishi Sinha, Jody Barditch, Tim Tully, Adrian R Krainer, Michael Q Zhang, Josh Dubnau
Publikováno v:
PLoS Computational Biology, Vol 4, Iss 2, p e1000026 (2008)
Drosophila Pumilio (Pum) protein is a translational regulator involved in embryonic patterning and germline development. Recent findings demonstrate that Pum also plays an important role in the nervous system, both at the neuromuscular junction (NMJ)
Externí odkaz:
https://doaj.org/article/9f2e4416206b43d68529a5b18dc65192
Autor:
Qing-Shuo, Zhang
Publikováno v:
Advances in experimental medicine and biology. 1083
Stem cell therapy is the administration of stem cells to a patient to treat or prevent a disease. Since stem cells possess the long-term self-renewal capacity and provide daughter cells that differentiate into the specialized cells of each tissue, st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d281c9bd77f2042aad6ce313860b81b
https://pubmed.ncbi.nlm.nih.gov/28687959
https://pubmed.ncbi.nlm.nih.gov/28687959
Autor:
Qing-Shuo Zhang
Publikováno v:
Stem Cells: Biology and Engineering ISBN: 9783319774817
Stem cell therapy is the administration of stem cells to a patient to treat or prevent a disease. Since stem cells possess the long-term self-renewal capacity and provide daughter cells that differentiate into the specialized cells of each tissue, st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53577340f6377f02333225d151fdb0a7
https://doi.org/10.1007/5584_2017_67
https://doi.org/10.1007/5584_2017_67
Autor:
Andrea N. Marcogliese, Ngoc Phan, Hui Li, Angela Major, Muhsen Al-Dhalimy, Markus Grompe, Raymond J. Monnat, Weiliang Tang, Qing Shuo Zhang, Susan B. Olson, Matthew Deater
Fanconi anemia (FA) is an inherited bone marrow failure disorder associated with a high incidence of leukemia and solid tumors. Bone marrow transplantation is currently the only curative therapy for the hematopoietic complications of this disorder. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e78457a391bfb696b930532fefbf32
https://europepmc.org/articles/PMC5159699/
https://europepmc.org/articles/PMC5159699/
Autor:
Jung Min Kim, Gérard Socié, Alan D. D'Andrea, Corinne Pondarré, Raphael Ceccaldi, Markus Grompe, Marie Regairaz, Qing Shuo Zhang, Jean Soulier, Thierry Leblanc, Régis Peffault de Latour, Enguerran Mouly, Eliane Gluckman, Jérôme Larghero, Marika Pla, Kalindi Parmar, Nadia Vasquez, Marc Delord, Marina Cavazzana-Calvo
Publikováno v:
Cell Stem Cell. 11(1):36-49
Summary Fanconi anemia (FA) is an inherited DNA repair deficiency syndrome. FA patients undergo progressive bone marrow failure (BMF) during childhood, which frequently requires allogeneic hematopoietic stem cell transplantation. The pathogenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34595a3e29317a5f48ceab6662ab1825
Autor:
Ngoc Phan, Andrea N. Marcogliese, Eva C. Guinan, Angela Major, Matthew Deater, Markus Grompe, Qing Shuo Zhang
Publikováno v:
Pediatric Blood & Cancer. 66:e27460
BACKGROUND: Fanconi anemia is an inherited bone marrow failure disorder associated with a high incidence of leukemia and solid tumors. Currently, no interventions to prevent or delay the formation of solid tumors are available. PROCEDURE: Two of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0650368149d4943a135cef44d06fa070
https://doi.org/10.1002/pbc.27460
https://doi.org/10.1002/pbc.27460