Zobrazeno 1 - 10
of 526
pro vyhledávání: '"Qing R"'
Autor:
Jialing Ma, Peng Zeng, Lipei Liu, Mengmeng Zhu, Juan Zheng, Chengyi Wang, Xiaokang Zhao, Wenquan Hu, Xiaoxiao Yang, Yajun Duan, Jihong Han, Qing R. Miao, Yuanli Chen
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Increased Nogo-B receptor (NGBR) expression in the liver improves insulin sensitivity by reducing endoplasmic reticulum stress (ER stress) and activating the AMPK pathway, although it remains elusive the mechanisms by which NGBR is induced. In this s
Externí odkaz:
https://doaj.org/article/2e75e4248f494f4c895923ceb78ad830
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Endothelial cell (EC), consisting of the innermost cellular layer of all types of vessels, is not only a barrier composer but also performing multiple functions in physiological processes. It actively controls the vascular tone and the extravasation
Externí odkaz:
https://doaj.org/article/4d91bda92ceb4074bc6a1fa367c50c45
Autor:
Wenquan Hu, Zhong Liu, Valerie Salato, Paula E. North, Joyce Bischoff, Suresh N. Kumar, Zhi Fang, Sujith Rajan, M. Mahmood Hussain, Qing R. Miao
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Infantile hemangioma is a vascular tumor characterized by the rapid growth of disorganized blood vessels followed by slow spontaneous involution. The underlying molecular mechanisms that regulate hemangioma proliferation and involution still are not
Externí odkaz:
https://doaj.org/article/e01edc80a8124f4bb805089613bbc913
Autor:
Ying Liu, Zhuo Wei, Xingzhe Ma, Xiaoxiao Yang, Yuanli Chen, Lei Sun, Chuanrui Ma, Qing R. Miao, David P. Hajjar, Jihong Han, Yajun Duan
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 3, Pp 439-451 (2018)
Cholesterol 25-hydroxylase (CH25H) catalyzes the production of 25-hydroxycholesterol (25-HC), an oxysterol that can play an important role in different biological processes. However, the mechanisms regulating CH25H expression have not been fully eluc
Externí odkaz:
https://doaj.org/article/7a35415dcb4345548725178c11011f23
Publikováno v:
eLife, Vol 8 (2019)
Inhibiting high-voltage-activated calcium channels (HVACCs; CaV1/CaV2) is therapeutic for myriad cardiovascular and neurological diseases. For particular applications, genetically-encoded HVACC blockers may enable channel inhibition with greater tiss
Externí odkaz:
https://doaj.org/article/e56ce6dd3efa4e69a83ce9aa4dcbc733
Autor:
Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Adrian R. Ferré-D'Amaré, J. Christopher Fromme, K. Christopher Garcia, Rachelle Gaudet, Peng Gong, Stephen C. Harrison, Ekaterina E. Heldwein, Zongchao Jia, Robert J. Keenan, Andrew C. Kruse, Marc Kvansakul, Jason S. McLellan, Yorgo Modis, Yunsun Nam, Zbyszek Otwinowski, Emil F. Pai, Pedro José Barbosa Pereira, Carlo Petosa, C. S. Raman, Tom A. Rapoport, Antonina Roll-Mecak, Michael K. Rosen, Gabby Rudenko, Joseph Schlessinger, Thomas U. Schwartz, Yousif Shamoo, Holger Sondermann, Yizhi J. Tao, Niraj H. Tolia, Oleg V. Tsodikov, Kenneth D. Westover, Hao Wu, Ian Foster, James S. Fraser, Filipe R. N C. Maia, Tamir Gonen, Tom Kirchhausen, Kay Diederichs, Mercè Crosas, Piotr Sliz
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The validation and analysis of X-ray crystallographic data is essential for reproducibility and the development of crystallographic methods. Here, the authors describe a repository for crystallographic datasets and demonstrate some of the ways it cou
Externí odkaz:
https://doaj.org/article/72383da3679147f9a2668c703d709d2e
Autor:
Yong Geng, Lidia Mosyak, Igor Kurinov, Hao Zuo, Emmanuel Sturchler, Tat Cheung Cheng, Prakash Subramanyam, Alice P Brown, Sarah C Brennan, Hee-chang Mun, Martin Bush, Yan Chen, Trang X Nguyen, Baohua Cao, Donald D Chang, Matthias Quick, Arthur D Conigrave, Henry M Colecraft, Patricia McDonald, Qing R Fan
Publikováno v:
eLife, Vol 5 (2016)
Human calcium-sensing receptor (CaSR) is a G-protein-coupled receptor (GPCR) that maintains extracellular Ca2+ homeostasis through the regulation of parathyroid hormone secretion. It functions as a disulfide-tethered homodimer composed of three main
Externí odkaz:
https://doaj.org/article/e63fb37743704af49f79c4f8b8cc2622
Autor:
Park, Jinseo, Zuo, Hao, Frangaj, Aurel, Fu, Ziao, Yen, Laura Y., Zhang, Zhening, Mosyak, Lidia, Slavkovich, Vesna N., Liu, Jonathan, Ray, Kimberly M., Cao, Baohua, Vallese, Francesca, Geng, Yong, Chen, Shaoxia, Grassucci, Robert, Dandey, Venkata P., Tan, Yong Zi, Eng, Edward, Lee, Yeji, Kloss, Brian, Liu, Zheng, Hendrickson, Wayne A., Potter, Clinton S., Carragher, Bridget, Graziano, Joseph, Conigrave, Arthur D., Frank, Joachim, Clarke, Oliver B., Fan, Qing R.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2021 Dec . 118(51), 1-10.
Externí odkaz:
https://www.jstor.org/stable/27117539
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Publikováno v:
In Journal of Proteomics 15 May 2020 219