Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Qing Qing Wu"'
Autor:
Chen Liu, Qi Yao, Tongtong Hu, Zhulan Cai, Qingwen Xie, Jinhua Zhao, Yuan Yuan, Jian Ni, Qing Qing Wu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 198-207 (2022)
Cathepsin B (CTSB), a member of lysosomal cathepsin, is involved in cell autophagy and apoptosis. We previously reported that CTSB increased cardiomyocyte apoptosis in mice heart during pressure overload, while the role of CTSB on diabetic cardiomyop
Externí odkaz:
https://doaj.org/article/eaa473eee22444c2aff5a4d99773ed1b
Autor:
Qingwen Xie, Qi Yao, Tongtong Hu, Zhulan Cai, Jinhua Zhao, Yuan Yuan, Qing Qing Wu, Qi-zhu Tang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
High-mobility group A1 (HMGA1) acts as a transcription factor in several cardiovascular diseases. However, the implications of HMGA1 in cardiac fibrosis remain unknown. Here, we investigated the impact of HMGA1 on cardiac fibrosis. A mouse cardiac fi
Externí odkaz:
https://doaj.org/article/28197148688f4022906dd573f8ef656d
Autor:
Chen Liu, Tongtong Hu, Zhulan Cai, Qingwen Xie, Yuan Yuan, Ning Li, Saiyang Xie, Qi Yao, Jinhua Zhao, Qing Qing Wu, Qizhu Tang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Nucleotide-binding oligomerization domain-like receptor 3 (NLRP3) is involved in fibrosis of multiple organs, such as kidney, liver, lung, and the like. However, the role of NLRP3 in cardiac fibrosis is still controversial and remains unclear. The st
Externí odkaz:
https://doaj.org/article/10e571681e7c4195a3a00a54d67c3c47
Autor:
Yu-zhou Gui, Wei Wang, Qing-qing Wu, Qi-chen Ding, Hong-jie Qian, Qiu-bei Lu, Ying-jun Zhang, Yu-lei Zhuang, Li Deng, Ying-lin Zuo, Lin Luo, Jing-ying Jia
Publikováno v:
Frontiers in Pharmacology; 2024, p1-14, 14p
Publikováno v:
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Cardiac fibrosis is a crucial aspect of cardiac remodeling that can severely affect cardiac function. Cardiac fibroblasts surely influence this process. Besides, macrophage plays an essential role in cardiac remodeling after heart
Externí odkaz:
https://doaj.org/article/0e608b664be34245887e14aa18c41c23
Autor:
Yan Liu, Li Wang, Yi-Ke Yang, Ying Liang, Tie-Juan Zhang, Na Liang, Li-Man Yang, Si-Jing Li, Dan Shan, Qing-Qing Wu
Publikováno v:
Diagnostic Pathology, Vol 14, Iss 1, Pp 1-13 (2019)
Abstract Background This study aims to provide genetic diagnoses for 30 cases of fetal skeletal dysplasia, and a molecular basis for the future prenatal diagnosis of fetal skeletal dysplasia. Methods A total of 30 cases of fetal skeletal dysplasia de
Externí odkaz:
https://doaj.org/article/9a35623931354243854a81e7d1a5cd69
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Objectives: Oral squamous cell carcinoma (OSCC) is the most common oral cancer with a poor prognosis owing to limited understanding of the disease mechanisms. The aim of this study was to explore and identify the potential biomarkers in OSCC by integ
Externí odkaz:
https://doaj.org/article/7b9eb26698044e2c92143ca4c9080020
Autor:
Qing-Run Li, Zi-Ming Wang, Nicolai J. Wewer Albrechtsen, Dan-Dan Wang, Zhi-Duan Su, Xian-Fu Gao, Qing-Qing Wu, Hui-Ping Zhang, Li Zhu, Rong-Xia Li, SivHesse Jacobsen, Nils Bruun Jørgensen, Carsten Dirksen, Kirstine N. Bojsen-Møller, Jacob S. Petersen, Sten Madsbad, Trine R. Clausen, Børge Diderichsen, Luo-Nan Chen, Jens J. Holst, Rong Zeng, Jia-Rui Wu
Publikováno v:
EBioMedicine, Vol 28, Iss C, Pp 234-240 (2018)
Roux-en-Y Gastric bypass surgery (RYGB) is emerging as a powerful tool for treatment of obesity and may also cause remission of type 2 diabetes. However, the molecular mechanism of RYGB leading to diabetes remission independent of weight loss remains
Externí odkaz:
https://doaj.org/article/69b5400ead8943388bbdbcdd2590f8fd
Publikováno v:
Journal of Pharmacological Sciences, Vol 135, Iss 4, Pp 156-163 (2017)
Since inhibiting cardiac remodeling is a critical treatment goal after myocardial infarction (MI), many drugs have been evaluated for this purpose. Acacetin is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflamm
Externí odkaz:
https://doaj.org/article/088c6381fa2648bdac9aaa7dfbb35503
Autor:
Di Fan, Zheng Yang, Fang-yuan Liu, Ya-Ge Jin, Ning Zhang, Jian Ni, Yuan Yuan, Hai-Han Liao, Qing-Qing Wu, Man Xu, Wei Deng, Qi-Zhu Tang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 6, Pp 2212-2227 (2017)
Background/Aims: Cardiac remodeling is associated with oxidative stress. Sesamin, a well-known antioxidant from sesamin seeds, have been used extensively as traditional health foods. However, there is little known about the effect of sesamin on cardi
Externí odkaz:
https://doaj.org/article/ae0dab7426db47faa43589f071bef104